Results 181 to 190 of about 4,270,323 (214)

Khellin-Derived Benzofuran-Pyrazoline Hybrids as Kinase-Targeted Anticancer Agents. [PDF]

ACS Omega
Al-Qadhi MA, Yahya TAA, Fahim SH, Ragab FAF.   +3 more
europepmc   +1 more source

RAF/MEK clamp inhibition with avutometinib and cetuximab in RAF1 S257L-mutated, anti-EGFR-refractory metastatic colorectal cancer in Gaucher's disease. [PDF]

Oncologist
Rose A, Rosenberg A, Grewal US, Brown TJ, Hornstein N.   +4 more
europepmc   +1 more source

Promoter methylation of Raf kinase inhibitory protein: A significant prognostic indicator for patients with gastric adenocarcinoma. [PDF]

Exp Ther Med, 2014
Li DX, Cai HY, Wang X, Feng YL, Cai SW.
europepmc   +1 more source

Mechanisms of Resistance to MEK Inhibitors (RAS-MAPK Pathway) in Malignant Peripheral Nerve Sheath Tumors and Their Precursor Lesions (Plexiform Neurofibromas) Associated with Neurofibromatosis Type 1. [PDF]

Cancers (Basel)
Sologov SI, Sologova D, Dubinin D, Anikin G, Bekhorashvili N, Rayisyan M, Krylova E, Yarkova M, Grigorevskikh EM, Smolyarchuk E, Sologova S.   +10 more
europepmc   +1 more source

Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein. [PDF]

Oncotarget, 2017
Buschow SI, Ramazzotti M, Reinieren-Beeren IMJ, Heinzerling LM, Westdorp H, Stefanini I, Beltrame L, Hato SV, Ellebaek E, Gross S, Nguyen VA, Weinlich G, Ragoussis J, Baban D, Schuler-Thurner B, Svane IM, Romani N, Austyn JM, De Vries IJM, Schuler G, Cavalieri D, Figdor CG.   +21 more
europepmc   +1 more source

Small-molecule RAS/RAF inhibitors target RAS-driven cancers via allosteric RAF disruption. [PDF]

Nat Commun
Yoshikawa Y, Kubota H, Matsumoto S, Makino Y, Kawamura T, Yuki H, Sakai N, Shibaike A, Okamura M, Fujimoto-Sakisaka W, Honda K, Horikawa T, Mori I, Okada M, Horikawa M, Horie K, Koyanagi-Aoi M, Aoi T, Kataoka T, Okada T, Tamura A, Honma T, Kumasaka T, Koyama H, Shima F.   +24 more
europepmc   +1 more source

Exploring the Neuroprotective Effects of Walnut (<i>Juglans regia</i> L.) Against Cognitive Impairment in Alzheimer's Disease Through the MAPK-mTORC1-TFEB-Mediated Endolysosomal Pathway: A Network Pharmacology and Molecular Docking Approach. [PDF]

Int J Mol Sci
Lin CT, Chen KT, Hung YC.
europepmc   +1 more source

Targeting MAPK Pathways in Skin, Thyroid, and Pancreatic Cancer: A Perspective on Synthetic Inhibitors and Natural Modulators. [PDF]

Adv Biol (Weinh)
Wasnik D, Swamy KV, Vyas R.
europepmc   +1 more source

Thiadiazolo-Triazolo-Pyrimidine Hybrids as Dual Aurora A/ERK Inhibitors: Design, Synthesis, and Apoptotic Activity. [PDF]

Drug Dev Res
Mourad MAE, Hofni A, Mourad AAE.
europepmc   +1 more source