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The anatomy of rage: conceptualization, operationalization, and validation of a new measurement scale [PDF]
IntroductionDespite its prevalence among gamers, rage remains an understudied phenomenon in digital gaming. The present study aimed to conceptualize rage as an emotional response to in-game failure or frustration and to develop a reliable and valid self ...
Natalia Michałkiewicz +2 more
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Alzheimer’s disease (AD) is a devastating neurodegenerative disorder and a leading cause of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as defining pathological features.
Yam Nath Paudel +2 more
exaly +3 more sources
Engineering an immune-integrated lung-on-a-chip to reveal TOX-RAGE axis-driven fibrosis and RAGE blockade as a therapeutic strategy. [PDF]
Kim H +8 more
europepmc +2 more sources
目的 探索阿司匹林和氯吡格雷联合应用对小鼠大脑中动脉远端缺血再灌注模型恢复期晚期糖基化终末产物受体(receptor for advanced glycation end products,RAGE)及可溶性晚期糖基化终末产物受体(soluble receptor for advanced glycation end products,sRAGE)表达的影响及其机制。 方法 60只C57BL/6J雄性小鼠随机分为假手术组、溶剂组、阿司匹林和氯吡格雷联合组(双抗组),每组20只 ...
温少红, 刘向荣, 顺英, 董雯, 陈青芳, 陈文涛, 李子孝, 王春娟
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The high-mobility group box 1 (HMGB1)/receptor for advanced glycation end products (RAGE) signaling pathway holds promise as a potential therapeutic target for ischemic brain injury. The effects of FPS-ZM1 and electroacupuncture (EA) on activation of the
Nie Zeyin +3 more
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For a Research Agenda on Negative Politics
This thematic issue deals with the “negative” side of politics, more specifically with dynamics of political aggressiveness and ideological opposition in voters and elites. Why do candidates “go negative” on their rivals?
Alessandro Nai +4 more
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MLKL Regulates Rapid Cell Death-independent HMGB1 Release in RSV Infected Airway Epithelial Cells
Respiratory syncytial virus (RSV)-induced bronchiolitis is a significant contributor to infant morbidity and mortality. Previously, we identified that necroptosis, a pro-inflammatory form of cell death mediated by receptor-interacting serine/threonine ...
Jennifer Simpson +5 more
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Redox Signaling and Advanced Glycation Endproducts (AGEs) in Diet-Related Diseases
Diets are currently characterized by elevated sugar intake, mainly due to the increased consumption of processed sweetened foods and drinks during the last 40 years. Diet is the main source of advanced glycation endproducts (AGEs).
Vanesa Cepas +3 more
doaj +1 more source
Bronchopulmonary dysplasia (BPD) is a common cause of pulmonary disease in preterm infants. The soluble receptor for advanced glycation end products (sRAGE) is implicated in the development of various pulmonary diseases.
Hayato Go +12 more
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Introduction: Aggressiveness is an essential component of every living thing and the experience of anger is common to all historical periods, all ages and all mental structures. Different forms and narrative ways of anger can be found in each society and
Paola Manfredi
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