Results 31 to 40 of about 454,799 (340)

Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamsters

Applied and Environmental Microbiology
Only a few studies have shown that certain probiotics have beneficial effects on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this study, two strains of Bifidobacterium breve, CNCM I-5644 and CNCM I-5979, selected for their ...
Edgar Torres-Maravilla, Marine Wasniewski, Aurélie Wauquier, Alexandre Servat, Evelyne Picard-Meyer, Elodie Monchatre-Leroy, Sandrine Auger, Sophie Holowacz, Franck Boué, Philippe Langella, Elsa Jacouton, Anne-Judith Waligora-Dupriet   +11 more
doaj   +1 more source

RAGE signalling in obesity and diabetes: focus on the adipose tissue macrophage

Adipocyte, 2020
The advanced glycosylation end product receptor (RAGE) acts as a recognition receptor and interacts with different types of ligands that form and accumulate in the tissues and circulation, such as diabetes, inflammation, insulin resistance, and obesity ...
Ziqian Feng, Luochen Zhu, Jianbo Wu
doaj   +1 more source

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer [PDF]

, 2015
High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm and extra-cellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system ...
ANTONACI, Alfredo, FAGGIONI, Alberto, Fico, F., MARDENTE, Stefania, MARI, EMANUELA, MASSIMI, ISABELLA, PULCINELLI, FABIO MARIA, ZICARI, Alessandra   +7 more
core   +4 more sources

Selfvergifnis – ’n Afgeskeepte area binne die pastoraat

In die Skriflig, 2020
Self-forgiveness – A neglected area within the pastorate: The scientific study of the theme of forgiveness in general, has only begun to gain momentum during the 1970s – it is thus a relatively new concept within the helping professions.
Wentzel C. Coetzer
doaj   +1 more source

Advanced glycation end-products (AGEs) induce concerted changes in the osteoblastic expression of their receptor RAGE and in the activation of extracellular signal-regulated kinases (ERK) [PDF]

, 2003
An increase in the interaction between advanced glycation end-products (AGEs) and their receptor RAGE is believed to contribute to the pathogenesis of chronic complications of Diabetes mellitus, which can include bone alterations such as osteopenia.
Barrio, D.A., Cortizo, Ana María, Etcheverry, S.B., Lettieri, M.G., McCarthy, Antonio Desmond, Mercer, N.   +5 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

La pasión explosiva: una conceptualización de la ira política

Revista de Estudios Sociales
In recent years, anger has emerged as a crucial category for analyzing contemporary political phenomena such as democratic elections, protests, collective violence, social movements, and crises of institutional representation. However, it has also become
Iván Garzón Vallejo
doaj   +1 more source

Low radon exposures and lung cancer risk: joint analysis of the Czech, French, and Beaverlodge cohorts of uranium miners. [PDF]

, 2019
It is well established that high radon exposures increase the risk of lung cancer mortality. The effects of low occupational exposures and the factors that confound and modify this risk are not clear and are needed to inform current radiation protection ...
Lane, Rachel SD, Little, Julian, Momoli, Franco, Rage, Estelle, Tomášek, Ladislav, Zablotska, Lydia B   +5 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source