Results 31 to 40 of about 48,769 (198)

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

Proceedings of the National Academy of Sciences of the United States of America, 1990
We transfected COS cells with cDNAs for the alpha subunits of stimulatory and inhibitory GTP-binding proteins, alpha s and alpha i1, respectively, and immunoprecipitated the metabolically labeled products with specific peptide antibodies.
Teresa L. Z. Jones, W. Simonds, J. J. Merendino, Mark R. Brann, Allen M. Spiegel   +4 more
semanticscholar   +1 more source

Identification of alternatively spliced MsRan transcripts involved in low temperature response in Musa spp.

Biologia Plantarum, 2017
Ran is involved in response to external stimuli. In this study, six MsRan gene cDNA sequences were isolated from wild banana (Musa spp. AB group) from Sanming City, China.
Y. L. Zhang, Z. Z. Fang, Z. X. Lai
doaj   +1 more source

Ran-GTP/-GDP-dependent nuclear accumulation of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 and TGACG-BINDING FACTOR2 controls salicylic acid-induced leaf senescence.

Plant Physiology, 2022
Leaf senescence is the final stage of leaf development and can be triggered by various external factors, such as hormones and light deprivation. In this study, we demonstrate that overexpression of the GTP-bound form of Arabidopsis (Arabidopsis thaliana)
Giang Pham, D. Shin, Yoon Kim, Soo-Hwan Kim   +3 more
semanticscholar   +1 more source

The methylated N-terminal tail of RCC1 is required for stabilisation of its interaction with chromatin by Ran in live cells

BMC Cell Biology, 2010
Background Regulator of chromosome condensation 1 (RCC1) is the guanine nucleotide exchange factor for Ran GTPase. Localised generation of Ran-GTP by RCC1 on chromatin is critical for nucleocytoplasmic transport, mitotic spindle assembly and nuclear ...
Sanderson Helen S, Hood Fiona E, Hitakomate Ekarat, Clarke Paul R   +3 more
doaj   +1 more source

Nup358, a Cytoplasmically Exposed Nucleoporin with Peptide Repeats, Ran-GTP Binding Sites, Zinc Fingers, a Cyclophilin A Homologous Domain, and a Leucine-rich Region (*)

Journal of Biological Chemistry, 1995
The Ras-related nuclear protein, Ran, has been implicated in nuclear transport. By screening a HeLa cell expression library with Ran-GTP and sequencing overlapping cDNA clones, we have obtained the derived primary structure of a protein with a calculated
Jian Wu, M. Matunis, D. Kraemer, G. Blobel, E. Coutavas   +4 more
semanticscholar   +1 more source

Signal Recognition Particle (SRP) and SRP Receptor: A New Paradigm for Multistate Regulatory GTPases [PDF]

, 2009
The GTP-binding proteins or GTPases comprise a superfamily of proteins that provide molecular switches in numerous cellular processes. The “GTPase switch” paradigm, in which a GTPase acts as a bimodal switch that is turned “on” and “off” by external ...
Schmid, Sandra L., Shan, Shu-ou, Zhang, Xin   +2 more
core   +2 more sources

A dynamic mode of mitotic bookmarking by transcription factors. [PDF]

, 2016
During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye, Darzacq, Xavier, Hansen, Anders S, Teves, Sheila S, Tjian, Robert, Xie, Liangqi   +5 more
core   +1 more source

Guanosine nucleotides regulate B2 kinin receptor affinity of agonists but not of antagonists: Discussion of a model proposing receptor precoupling to G protein [PDF]

, 2000
The effect of nucleotides on binding of the B2 kinin (BK) receptor agonist {[}H-3]BK and the antagonist {[}H-3]NPC17731 to particulate fractions of human foreskin fibroblasts was studied.
Faussner, Alexander, Roscher, Adelbert A.   +1 more
core   +1 more source

Mitochondrial Protein Import [PDF]

, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Arends, Argan, Argan, Bogner, Bogner, Bradford, Böhni, Böhni, Chamberlain, Chen, Chen, Conboy, Eilers, Emr, Firgaira, Flügge, Frank, Gasser, Geller, Grossman, Gubler, Hanahan, Hansen, Harmey, Hartl, Hay, Hennig, Hennig, Horwich, Hurt, Hurt, Jaenicke, Keng, Kolanski, Maniatis, McAda, Miura, Miura, Mueckler, Nicholls, Nunberg, Ohta, Pelham, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Randall, Riezman, Roise, Rothblatt, Rothman, Schlenstedt, Schleyer, Schleyer, Schleyer, Schmidt, Schmidt, Schwaiger, Sebald, Stueber, van Loon, van Loon, Viebrock, Waters, Wiech, Wikstrom, Zimmermann, Zimmermann, Zwizinski, Zwizinski, Zwizinski   +72 more
core   +1 more source

Small GTP-binding protein PdRanBP regulates vascular tissue development in poplar

BMC Genetics, 2016
BackgroundPrevious research has demonstrated that ectopic expression of Ran-binding protein (RanBP) in Arabidopsis results in more axillary buds and reduced apical dominance compared to WT plants.
Shaofeng Li, Qinjun Huang, Bing-Yu Zhang, Jianhui Zhang, Xue Liu, Mengzhu Lu, Zanmin Hu, Changjun Ding, Xiaohua Su   +8 more
semanticscholar   +2 more sources