Alteration in endometrial proteins during early- and mid-secretory phases of the cycle in women with unexplained infertility. [PDF]
PLoS ONE, 2014 BACKGROUND: Compromised receptivity of the endometrium is a major cause of unexplained infertility, implantation failure and subclinical pregnancy loss.
Murli Manohar +7 more
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Frontiers in Oncology, 2023 IntroductionArtemisia absinthium (wormwood) exhibits anticancer properties by inhibiting proliferation and causing cell death in breast cancer. Targeted drug delivery of A. absinthium nanoformulation using N-isopropyl acrylamide, N-vinyl pyrrolidone, and
Sana Kauser +4 more
doaj +1 more source
The F-actin filament capping protein CapG is a bona fide nucleolar protein [PDF]
, 2008 Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the question how actin dynamics is regulated in the nucleolus ...
Gettemans, Jan +3 more
core +2 more sources
Structural Insights into How Yrb2p Accelerates the Assembly of the Xpo1p Nuclear Export Complex
Cell Reports, 2014 Proteins and ribonucleoproteins containing a nuclear export signal (NES) assemble with the exportin Xpo1p (yeast CRM1) and Gsp1p-GTP (yeast Ran-GTP) in the nucleus and exit through the nuclear pore complex.
Masako Koyama +2 more
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A disappearing act performed by magnesium: the nucleotide exchange mechanism of Ran GTPase by Quantum mechanics/Molecular mechanics studies [PDF]
, 2016 The Ran GTPase protein is a guanine nucleotide-binding protein (GNBP) with an acknowledged profile in cancer onset, progression and metastases. The complex mechanism adopted by GNBPs in exchanging GDP for GTP is an intriguing process and crucial for Ran ...
Huang, Meilan +3 more
core +1 more source
Comparative Proteomic Analysis of Anti-Cancer Mechanism by Periplocin Treatment in Lung Cancer Cells
Cellular Physiology and Biochemistry, 2014 Background: Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine. Our previous findings suggested that periplocin could inhibit
Zejun Lu +6 more
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Structural insight into TPX2-stimulated microtubule assembly [PDF]
, 2017 During mitosis and meiosis, microtubule (MT) assembly is locally upregulated by the chromatin-dependent Ran-GTP pathway. One of its key targets is the MT-associated spindle assembly factor TPX2.
Nogales, Eva +3 more
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GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]
, 2015 The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna +6 more
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The RanGTP pathway: from nucleo-cytoplasmic transport to spindle assembly and beyond
Frontiers in Cell and Developmental Biology, 2016 The small GTPase Ran regulates the interaction of transport receptors with a number of cellular cargo proteins. The high affinity binding of the GTP-bound form of Ran to import receptors promotes cargo release, whereas its binding to export receptors ...
Tommaso eCavazza +4 more
doaj +1 more source
Topological and functional properties of the small GTPases protein interaction network. [PDF]
PLoS ONE, 2012 Small GTP binding proteins of the Ras superfamily (Ras, Rho, Rab, Arf, and Ran) regulate key cellular processes such as signal transduction, cell proliferation, cell motility, and vesicle transport.
Anna Delprato
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