Increasing recruitment to randomised trials: a review of randomised controlled trials [PDF]
Poor recruitment to randomised controlled trials (RCTs) is a widespread and important problem. With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective.We searched the register of
Judith Watson, David J. Torgerson
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Circuit bases for randomisation [PDF]
After a rich history in medicine, randomisation control trials both simple and complex are in increasing use in other areas such as web-based AB testing and planning and design decisions. A main objective is to be able to measure parameters, and contrasts in particular, while guarding against biases from hidden confounders. After careful definitions of
arxiv
Randomised controlled trials [PDF]
Randomised controlled trials , Alejandro Jadad, pp 128. BMJ Books, 1998. £12.95 (£11.95 to BMA members), paperback. ISBN 0 7279 1208 9. ★★★ The issue of trial design is increasingly recognised as central to the evaluation of the benefit from any healthcare intervention.
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A randomised controlled trial of cognitive behavioural treatment for obsessive compulsive disorder in children and adolescents [PDF]
Cognitive behaviour therapy (CBT) for young people with obsessive compulsive disorder (OCD) has become the treatment of first choice. However, the literature is largely based on studies emphasising exposure and response prevention.
A Mather+40 more
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A Randomised Controlled Trial [PDF]
Liver surgery is still associated with a high rate of morbidity and mortality. We aimed to compare different haemodynamic treatments in liver surgery. In a prospective, blinded, randomised, controlled pilot trial patients undergoing liver resection were ...
Feldheiser, Aarne+8 more
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The association between registration status and reported outcomes in physiotherapy randomised controlled trials [PDF]
Background/Aims: Clinical trial registration has been proposed as a method of mitigating selective reporting in scientific research. It remains unknown whether trial registration is associated with reported outcomes in physiotherapy trials.
Cross, Jl+4 more
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Generating the right evidence at the right time: Principles of a new class of flexible augmented clinical trial designs [PDF]
The past few years have seen an increasing number of initiatives aimed at integrating information generated outside of confirmatory randomised clinical trials (RCTs) into drug development. However, data generated non-concurrently and through observational studies can provide results that are difficult to compare with randomised trial data.
arxiv
A single blind, multicenter, randomized controlled trial to evaluate the effectiveness and cost of a novel nutraceutical (LopiGLIK®) lowering cardiovascular disease risk [PDF]
Context: Cardiovascular disease (CVD) costs the economy €210 billion per year in Europe. There is an association between low-density lipoprotein cholesterol (LDL-C) and CVD risk.
Izzo, Raffaele+4 more
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A randomised controlled trial to evaluate and optimize the use of antiplatelet agents in the perioperative management in patients undergoing general and abdominal surgery- the APAP trial (ISRCTN45810007) [PDF]
Background Due to the increase of cardiovascular diseases acetylsalicylic acid (ASA) has become one of the most frequently prescribed drugs these days.
A Tiede+20 more
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Journeying through dementia randomised controlled trial of a psychosocial intervention for people living with early dementia: embedded qualitative study with participants, carers and interventionists [PDF]
Objective: To identify the barriers and facilitators to the implementation of a complex psychosocial intervention though a study exploring the experiences of participants, carers and interventionists during a trial. Methods: Individual semi-structured
Beresford-Dent, J.+6 more
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