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Randomized Controlled Trials [PDF]
Randomized controlled trials (RCTs) are considered the highest level of evidence to establish causal associations in clinical research. There are many RCT designs and features that can be selected to address a research hypothesis. Designs of RCTs have become increasingly diverse as new methods have been proposed to evaluate increasingly complex ...
Emily C. Zabor+2 more
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Electroacupuncture Treatment for Primary Dysmenorrhea: A Review of Randomized Controlled Trials [PDF]
To evaluate the effectiveness of electroacupuncture treatment for primary dysmenorrhea (PD), a literature review of a randomized controlled trials (RCTs) was performed where electroacupuncture was used as a treatment intervention in patients diagnosed ...
Myung Kyu Jeon+12 more
doaj +1 more source
Development of a New Remote Diagnosis and Treatment Model for Obstructive Sleep Apnea: a Non-inferiority Randomized Controlled Trial Protocol [PDF]
Obstructive sleep apnea (OSA) is a high prevalent chronic disease that may lead to many complications, and cause great potential harm to health. Epidemiological studies have showed that OSA is closely related to the development of various cardiovascular ...
YI Huijie, LIAO Xinyi, PI Mengyuan, XU liyue, ZHANG Chi, DONG Xiaosong, HAN Fang
doaj +1 more source
The European Academy of Rehabilitation Medicine (EARM) held a debate in Hannover, Germany, on 1st of September 2016 on the pros and cons of randomized controlled trials (RCTs) and observational effectiveness studies (benchmarking controlled trials ...
A. Malmivaara+3 more
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Randomized controlled trials [PDF]
Proponents of evidence-based medicine would acknowledge that several sources of evidence inform clinical decision making. Hierarchies of evidence have, however, been developed to help describe the quality of evidence that may be found to answer our clinical questions. According to this classification, the randomized clinical trial is the most effective
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What’s new for the clinician? - Excerpts from and summaries of recently published papers [PDF]
0.5% versus 3% sodium hypochlorite (NaOCl) in root canal treatment: A quasi-randomized controlled trial/ C Ulin, M Magunacelaya-Barria, G Dahlén, T Kvist.
Yengopal, Veerasamy
core +15 more sources
Salt intake and blood pressure in Iranian children and adolescents: a population-based study
Background Previous studies have reported a high prevalence of hypertension in Iranian students, especially in rural areas. The aim of this study was to investigate the daily intake of salt in students and its association with high blood pressure ...
Mohammad Hassan Emamian+3 more
doaj +1 more source
Background Isolated systolic hypertension (ISH), is the most common form of hypertension in older adults. However, the ISH prevalence is not well known in many developing countries such as Iran.
Ali Hosseinzadeh+5 more
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The Randomized Controlled Trial [PDF]
Until recently, high-quality randomized controlled trials (RCTs) have rarely been performed in nephrology, because of several difficulties in conducting an RCT. The purpose of this article is to describe several issues related to the design and to the quality of RCTs in their conduct, analysis, interpretation, and reporting of the results.
Vianda S. Stel+3 more
openaire +3 more sources
Non-inferiority clinical trials: importance and applications in health sciences [PDF]
Non-inferiority randomized clinical trials are indicated when it is intended to prove that an experimental group is not inferior to a control group by more than a margin of non-inferiority.
Heitor Marques HONÓRIO+2 more
doaj +1 more source