Results 131 to 140 of about 4,106,658 (410)

A Randomized, Controlled Trial of Fusion Surgery for Lumbar Spinal Stenosis.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND The efficacy of fusion surgery in addition to decompression surgery in patients who have lumbar spinal stenosis, with or without degenerative spondylolisthesis, has not been substantiated in controlled trials.
P. Försth   +8 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

What is the best way to manage benign paroxysmal positional vertigo? [PDF]

open access: yes, 2003
A simple repositioning maneuver, such as the Epley maneuver, performed by an experienced clinician, can provide symptom relief from benign paroxysmal positional vertigo (BPPV) lasting at least 1 month (strength of recommendation [SOR]: A, systematic ...
Russell, Roger G., Strickland, Carmen
core  

Home-based reach-to-grasp training for people after stroke: study protocol for a feasibility randomized controlled trial [PDF]

open access: yes, 2013
BackgroundThis feasibility study is intended to assess the acceptability of home-based task-specific reach-to-grasp (RTG) training for people with stroke, and to gather data to inform recruitment, retention, and sample size for a definitive randomized ...
Cunningham, Paul   +9 more
core   +1 more source

The care transitions intervention: results of a randomized controlled trial.

open access: yesArchives of Internal Medicine, 2006
BACKGROUND Patients with complex care needs who require care across different health care settings are vulnerable to experiencing serious quality problems.
E. Coleman   +3 more
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Pitfalls of Randomized Controlled Trials in Stroke: How Can We Do Better?

open access: yesStroke: Vascular and Interventional Neurology, 2023
Shadi Yaghi   +2 more
doaj   +1 more source

Does physical therapy improve symptoms of fibromyalgia? [PDF]

open access: yes, 2003
Physical therapy is minimally effective in the treatment of fibromyalgia, with immediate post-treatment improvement in pain and tender points, and both short- and longer-term improved self-efficacy (confidence in performing tasks) (strength of ...
Gokula, Radha Ramana Murthy   +2 more
core  

Vitamin D with Calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials [PDF]

open access: yes, 2012
Introduction: Vitamin D may affect multiple health outcomes. If so, an effect on mortality is to be expected. Using pooled data from randomized controlled trials, we performed individual patient data (IPD) and trial level meta-analyses to assess ...
Abrahamsen, Bo   +17 more
core   +1 more source

Early Versus Delayed Initiation of Concurrent Palliative Oncology Care: Patient Outcomes in the ENABLE III Randomized Controlled Trial.

open access: yesJournal of Clinical Oncology, 2015
PURPOSE Randomized controlled trials have supported integrated oncology and palliative care (PC); however, optimal timing has not been evaluated. We investigated the effect of early versus delayed PC on quality of life (QOL), symptom impact, mood, 1-year
M. Bakitas   +11 more
semanticscholar   +1 more source

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