Likelihood reweighting methods to reduce potential bias in noninferiority trials which rely on historical data to make inference [PDF]
Annals of Applied Statistics 2013, Vol. 7, No. 3, 1796-1813, 2013 It is generally believed that bias is minimized in well-controlled randomized clinical trials. However, bias can arise in active controlled noninferiority trials because the inference relies on a previously estimated effect size obtained from a historical trial that may have been conducted for a different population.
Chu, Jianxiong +3 more
arxiv +3 more sources
A randomized controlled trial [PDF]
, 2017 Objective We report on the effect of hemoadsorption therapy to reduce cytokines in septic patients with respiratory failure. Methods This was a randomized, controlled, open-label, multicenter trial.
Brederlau, Joerg +6 more
core +4 more sources
What’s new for the clinician? - Excerpts from and summaries of recently published papers [PDF]
, 2020 0.5% versus 3% sodium hypochlorite (NaOCl) in root canal treatment: A quasi-randomized controlled trial/ C Ulin, M Magunacelaya-Barria, G Dahlén, T Kvist.
Yengopal, Veerasamy
core +15 more sources
A Randomized Double-blind Controlled Trial of Lactobacillus acidophilus Plus Bifidobacterium bifidum versus Placebo in Patients with Hypercholesterolemia [PDF]
Journal of Clinical and Diagnostic Research, 2015 Background: Hypercholesterolemia is a major risk factor for cardiovascular disease. Not all patients respond well to traditional cholesterol lowering medications.
Sanguansak Rerksuppaphol +1 more
doaj +1 more source
A randomized controlled trial and economic evaluation of the Parents Under Pressure Program for parents in substance abuse treatment [PDF]
, 2019 Background There is growing interest in the provision of parenting support to substance misusing parents. Methods This pragmatic, multi-center randomized controlled trial compared an intensive one-to-one parenting program (Parents under Pressure,
Barlow, Jane +6 more
core +1 more source
Randomized Controlled Trial [PDF]
, 2017 Background: Depression is highly prevalent in the working population and is associated with significant loss of workdays; however, access to evidence- based treatment is limited.
Beiwinkel, Till +4 more
core +1 more source
Analysis of Clinical Research Trends for Thread Embedding Acupuncture of Cervical Radiculopathy [PDF]
Journal of Acupuncture Research, 2022 In this study, the evidence of thread embedding acupuncture (TEA) in treating cervical radiculopathy in randomized controlled trials was investigated. We searched 16 databases up to August 22, 2022.
Eun Sil Heo +6 more
doaj +1 more source
Randomized controlled trials [PDF]
Journal of British Surgery, 1994 Definition The radial arm maze, originally developed by David Olton, is an apparatus that taps into natural foraging abilities of rodents and can be used to test different types of memory, including short-term (working), longterm (reference), nonspatial and spatial memory.
J. R. Farndon +4 more
openaire +1 more source
Dermatology and Randomized Control Trials
Indian Dermatology Online Journal, 2021 Well-designed and rigorously conducted randomized controlled trial (RCT) can produce most valid and precise scientific evidence. Any intervention, be it systemic or topical medicine, dermatology procedure needs to be tested for its efficacy in improving particular disease condition and RCT should come into mind of investigator.
Amrita Sil +1 more
openaire +3 more sources
Extraction socket preservation using porcine-derived collagen membrane alone or associated with porcine-derived bone. Clinical results of randomized controlled study [PDF]
, 2017 The aim of present randomized controlled clinical trial was to clinically evaluate hard tissue changes after extraction socket preservation procedures compared to natural spontaneous ...
De Angelis, Francesca +5 more
core +2 more sources