Results 31 to 40 of about 4,008,309 (403)

Dermatology and Randomized Control Trials

Indian Dermatology Online Journal, 2021
Well-designed and rigorously conducted randomized controlled trial (RCT) can produce most valid and precise scientific evidence. Any intervention, be it systemic or topical medicine, dermatology procedure needs to be tested for its efficacy in improving particular disease condition and RCT should come into mind of investigator.
Amrita Sil, Nayankumar Harshadkumar Patel   +1 more
openaire   +3 more sources

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics.

New England Journal of Medicine, 2019
BACKGROUND Although several experimental therapeutics for Ebola virus disease (EVD) have been developed, the safety and efficacy of the most promising therapies need to be assessed in the context of a randomized, controlled trial.
S. Mulangu, L. Dodd, R. Davey, Olivier Tshiani Mbaya, M. Proschan, Daniel Mukadi, Mariano Lusakibanza Manzo, Didier Nzolo, Antoine Tshomba Oloma, Augustin Ibanda, Rosine Ali, Sinaré Coulibaly, A. Levine, R. Grais, Janet Diaz, H. Lane, J. Muyembe-Tamfum, Billy Sivahera, Modet Camara, R. Kojan, R. Walker, Bonnie Dighero-kemp, H. Cao, Philippe Mukumbayi, Placide Mbala-Kingebeni, Steve Ahuka, S. Albert, Tyler Bonnett, Ian Crozier, Michael Duvenhage, C. Proffitt, M. Teitelbaum, T. Moench, J. Aboulhab, K. Barrett, Kelly Cahill, Katherine Cone, R. Eckes, L. Hensley, B. Herpin, E. Higgs, J. Ledgerwood, J. Pierson, M. Smolskis, Ydrissa Sow, J. Tierney, S. Sivapalasingam, W. Holman, Nikki Gettinger, D. Vallée, J. Nordwall   +50 more
semanticscholar   +1 more source

A randomized controlled trial and economic evaluation of the Parents Under Pressure Program for parents in substance abuse treatment [PDF]

, 2019
Background There is growing interest in the provision of parenting support to substance misusing parents. Methods This pragmatic, multi-center randomized controlled trial compared an intensive one-to-one parenting program (Parents under Pressure,
Barlow, Jane, Dawe, Sharon, Harnett, Paul, Kim, Sungwook, Parsons, Helen, Petrou, Stavros, Sembi, Sukhdev   +6 more
core   +1 more source

Noninvasive vagus nerve stimulation as acute therapy for migraine. The randomized PRESTO study [PDF]

, 2018
Objective: To evaluate the efficacy, safety, and tolerability of noninvasive vagus nerve stimulation (nVNS; gammaCore; electroCore, LLC, Basking Ridge, NJ) for the acute treatment of migraine in a multicenter, double-blind, randomized, sham-controlled ...
Ambrosini, Anna, Barbanti, Piero, De Tommaso, Marina, Dorlas, Stefanie, Geppetti, Pierangelo, Grazzi, Licia, Liebler, Eric, Martelletti, Paolo, Negro, Andrea, Pierangeli, Giulia, Rainero, Innocenzo, Sarchielli, Paola, Tassorelli, Cristina   +12 more
core   +2 more sources

Randomized Controlled Trials [PDF]

International Journal of Regional Anaesthesia, 2021
A randomized controlled trial (RCT) is a prospective, comparative, quantitative experiment/study that is performed under controlled conditions with random allocation of interventions to comparison groups. Among all the clinical study designs, evidence generated from RCTs is considered to be at top of the evidence pyramid.
Anju Grewal, Nidhi Bhatia
openaire   +2 more sources

Improving end-of-life care in acute geriatric hospital wards using the Care Programme for the Last Days of Life : study protocol for a phase 3 cluster randomized controlled trial [PDF]

, 2015
Background: The Care Programme for the Last Days of Life has been developed to improve the quality of end-of-life care in acute geriatric hospital wards.
Cohen, Joachim, Costantini, Massimo, Deliens, Luc, Smets, Tinne, Van Den Noortgate, Nele, Verhofstede, Rebecca   +5 more
core   +2 more sources

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

Journal of Psychopharmacology, 2016
Background: Clinically significant anxiety and depression are common in patients with cancer, and are associated with poor psychiatric and medical outcomes. Historical and recent research suggests a role for psilocybin to treat cancer-related anxiety and
Stephen Ross, Anthony P. Bossis, Jeffrey R. Guss, G. Agin-Liebes, T. Malone, Barry H Cohen, S. Mennenga, Alexander B. Belser, K. Kalliontzi, J. Babb, Zhe Su, P. Corby, B. Schmidt   +12 more
semanticscholar   +1 more source

A new parenting-based group intervention for young anxious children: results of a randomized controlled trial [PDF]

, 2011
Objective Despite recent advances, there are still no interventions that have been developed for the specific treatment of young children who have anxiety disorders.
Cartwright-Hatton, Sam, Dixon, Clare, Field, Andy P, Gallagher, Bridie, Harrington, Richard, Laskey, Ben, McNally, Deb, Miller, Chloe, Pemberton, Kathryn, Rust, Stewart, Symes, Wendy, White, Caroline, Woodham, Adrine   +12 more
core   +1 more source

Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia

JCSM Rapid Communications, 2022
Background Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC.
David Blum, Caroline Hertler, Rolf Oberholzer, Susanne deWolf‐Linder, Markus Joerger, Christoph Driessen, Florian Strasser   +6 more
doaj   +1 more source

Malaria positivity following a single oral dose of azithromycin among children in Burkina Faso: a randomized controlled trial

BMC Infectious Diseases, 2022
Background Azithromycin is a broad-spectrum antibiotic that has moderate antimalarial activity and has been shown to reduce all-cause mortality when biannually administered to children under five in high mortality settings in sub-Saharan Africa.
Jessica Brogdon, Clarisse Dah, Ali Sié, Mamadou Bountogo, Boubacar Coulibaly, Idrissa Kouanda, Mamadou Ouattara, Guillaume Compaoré, Eric Nebie, Mariam Seynou, Elodie Lebas, Fanice Nyatigo, Huiyu Hu, Benjamin F. Arnold, Thomas M. Lietman, Catherine E. Oldenburg   +15 more
doaj   +1 more source