Results 31 to 40 of about 4,120,157 (359)

Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]

, 2012
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H., Cooke, Matthew, Hawkey, P. M., Hong, Tan, Jones, Alan, Linhartova, Lucie, Melody, Teresa, Patel, Jaimin M., Perkins, Gavin D., Smith, F. Gao, Snaith, Catherine, Thickett, David R.   +11 more
core   +3 more sources

Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial

BMC Musculoskeletal Disorders, 2022
Background Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA.
Guangfeng Ruan, Shiwen Yuan, Aiju Lou, Yingqian Mo, Yuan Qu, Dongmei Guo, Shangqi Guan, Yan Zhang, Xiaoyong Lan, Jun Luo, Yifang Mei, Hongwei Zhang, Weirong Wu, Lie Dai, Qinghong Yu, Xiaoyan Cai, Changhai Ding   +16 more
doaj   +1 more source

Comparison between epley and gans repositioning maneuvers for posterior canal BPPV: A randomized controlled trial

Annals of Indian Academy of Neurology, 2023
Objectives: Benign paroxysmal positional vertigo (BPPV) is a condition in which a patient gets severe vertigo on moving his head from one position to another.
Neetu R Dhiman, Deepika Joshi, Vyom Gyanpuri, Abhishek Pathak, Anand Kumar   +4 more
doaj   +1 more source

Reflections on Digital Simulation in Dental Morphology Education: Insights from a Randomized Controlled Trial. [PDF]

Int Dent J
Ardila CM, Vivares-Builes AM, Vélez EP.
europepmc   +2 more sources

A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.

New England Journal of Medicine
BACKGROUND Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with no approved treatment. Resmetirom is an oral, liver-directed, thyroid hormone receptor beta-selective agonist in development for the treatment of NASH with liver fibrosis.
Stephen A. Harrison, P. Bedossa, Cynthia Guy, J. Schattenberg, Rohit Loomba, R. Taub, D. Labriola, S. Moussa, Guy W. Neff, M. Rinella, Q. Anstee, M. Abdelmalek, Z. Younossi, Seth J Baum, Sven M. Francque, Michael R. Charlton, Philip N. Newsome, N. Lanthier, Ingolf Schiefke, Alessandra Mangia, J. M. Pericàs, Rashmee Patil, Arun J. Sanyal, M. Noureddin, Meena B Bansal, N. Alkhouri, Laurent Castera, M. Rudraraju, V. Ratziu   +28 more
semanticscholar   +1 more source

Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial

Clinical Infectious Diseases, 2020
BACKGROUND No therapeutics have yet been proven effective for the treatment of mild-illness caused by SARS-CoV-2. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be more efficacious than no-treatment for outpatients with
O. Mitjà, M. Corbacho-Monné, Maria Ubals, C. Tebé, J. Peñafiel, A. Tobías, E. Ballana, A. Alemany, Núria Riera-Martí, C. A. Pérez, Clara Suñer, P. Laporte, Pol Admella, J. Mitjà, M. Clua, Laia Bertran, Maria Sarquella, Sergi Gavilán, J. Ara, J. Argimón, J. Casabona, G. Cuatrecasas, P. Cañadas, Aleix Elizalde-Torrent, Robert Fabregat, M. Farré, A. Forcada, G. Flores-Mateo, E. Muntada, Núria Nadal, S. Narejos, A. Nieto, N. Prat, J. Puig, C. Quiñones, Juliana Reyes-Ureña, Ferran Ramírez-Viaplana, L. Ruíz, E. Riveira-Muñoz, A. Sierra, C. Velasco, R. M. Vivanco-Hidalgo, A. Sentís, Camila G-Beiras, B. Clotet, M. Vall-Mayans   +45 more
semanticscholar   +1 more source

Comparing the Effects of Hot Shower and Intravenous Injection of Hyoscine on the Pain Intensity and Duration of Active Phase of Labour in Nulliparous Women [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Parturition is a painful process and one of midwives’ duties is to reduce the pain during labour. Aim: To compare the effect of hot shower and intravenous injection of hyoscine on the pain severity and duration of active phase of labour ...
Safa Maddady Maddady, Sakineh Mohammad-Alizadeh-Charandabi, Fahimeh Sehhatti Shafaei, Mojgan Mirghafourvand   +3 more
doaj   +1 more source

Results from a randomized controlled trial testing StressProffen; an application‐based stress‐management intervention for cancer survivors

Cancer Medicine, 2020
In‐person cognitive‐behavioral stress‐management interventions are consistently associated with reduced cancer distress. However, face‐to‐face delivery is an access barrier for many patients, and there is a need to develop remote‐delivered interventions.
Elin Børøsund, S. Ehlers, C. Varsi, M. Clark, M. Andrykowski, M. Cvancarova, Lise Solberg Nes   +6 more
semanticscholar   +1 more source

Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot):study protocol for a randomized controlled trial [PDF]

, 2014
Background: Parkinson’s disease is a common movement disorder affecting approximately 127,000 people in the UK, with an estimated two thirds having speech-related problems.
Brady, Marian C, Clarke, Carl, Dowling, Francis, Ives, Natalie, Jowett, Sue, Kelly, Debbie, Patel, Ramilla, Patel, Smitaa, Rick, Caroline, Roberts, Helen, Sackley, Catherine M, Sands, Gina, Smith, Christina H, Wheatley, Keith   +13 more
core   +4 more sources

Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial

Hypertension in Pregnancy, 2017
Objective: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension.
Kathryn J. Sharma, Naomi Greene, Sarah J. Kilpatrick   +2 more
doaj   +1 more source