Results 41 to 50 of about 4,106,658 (410)
Annals of Indian Academy of Neurology, 2023 Objectives: Benign paroxysmal positional vertigo (BPPV) is a condition in which a patient gets severe vertigo on moving his head from one position to another.
Neetu R Dhiman +4 more
doaj +1 more source
Effectiveness of 4 Pulpotomy Techniques—Randomized Controlled Trial [PDF]
, 2005 Pulpotomy is the accepted therapy for the management of cariously exposed pulps in symptom-free primary molars; however, evidence is lacking about the most appropriate technique.
Crispin, A. +6 more
core +1 more source
Lifestyle matters randomized controlled trial of a preventive health intervention for older people: Qualitative sub study with participants and intervention facilitators [PDF]
, 2020 © 2020 Mountain et al. Objective: This qualitative study embedded within a randomized controlled trial was conducted to explore the acceptability, experiences of, and short-term impact of a preventive health intervention (Lifestyle Matters) from the ...
Chatters, Robin +2 more
core +2 more sources
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
New England Journal of Medicine, 2015 BACKGROUND Obesity is a chronic disease with serious health consequences, but weight loss is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like peptide-1 analogue, has been shown to have potential benefit for weight ...
X. Pi-Sunyer +10 more
semanticscholar +1 more source
Iranian Journal of Nursing and Midwifery Research, 2020 Background: Randomized Controlled Trials (RCTs) are reliable methods for the evaluation of treatment effectiveness, which should be rigorous and must report with clarity.
Elham Manouchehri +2 more
doaj +1 more source
Journal of Indian Association of Public Health Dentistry, 2022 Background: Different toothpastes of the corresponding active ingredients could have variable extent of effectiveness; this raises the amount of choices with the marketplace for toothpaste containing these agents and makes it more difficult to gauge ...
Sneha Nachu +2 more
doaj +1 more source
Combining Real-World and Randomized Control Trial Data Using Data-Adaptive Weighting via the On-Trial Score [PDF]
arXiv, 2021 Clinical trials with a hybrid control arm (a control arm constructed from a combination of randomized patients and real-world data on patients receiving usual care in standard clinical practice) have the potential to decrease the cost of randomized trials while increasing the proportion of trial patients given access to novel therapeutics. However, due
arxiv
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis.
New England Journal of Medicine, 2006 BACKGROUND Natalizumab is the first alpha4 integrin antagonist in a new class of selective adhesion-molecule inhibitors. We report the results of a two-year phase 3 trial of natalizumab in patients with relapsing multiple sclerosis.
C. Polman +13 more
semanticscholar +1 more source
Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial
Clinical Infectious Diseases, 2020 BACKGROUND No therapeutics have yet been proven effective for the treatment of mild-illness caused by SARS-CoV-2. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be more efficacious than no-treatment for outpatients with
O. Mitjà +45 more
semanticscholar +1 more source
Adaptive Cohort Size Determination Method for Bayesian Optimal Interval Phase I/II Design to Shorten Clinical Trial Duration [PDF]
arXiv, 2023 Recently, the strategy for dose optimization in oncology has shifted to conduct Phase 2 randomized controlled trials with multiple doses. Optimal biologic dose selection from Phase 1 trial data to determine candidate doses for Phase 2 trials has been gaining attention.
arxiv