Conditional average treatment effect estimation with marginally constrained models [PDF]
, 2022 Treatment effect estimates are often available from randomized controlled trials as a single average treatment effect for a certain patient population. Estimates of the conditional average treatment effect (CATE) are more useful for individualized treatment decision making, but randomized trials are often too small to estimate the CATE.
arxiv +1 more source
a pilot randomized controlled trial [PDF]
, 2015 Objectives: Our primary aim of this pilot study was to test feasibility of the planned design, the interventions (education plus telephone coaching), and the outcome measures, and to facilitate a power calculation for a future randomized controlled ...
Ashe, M. C. +9 more
core +1 more source
Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression [PDF]
Multiple Sclerosis Journal, 19(12):1580-1586, 2013, 2013 Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS). Methods: We conducted a systematic literature search of RCTs in RMS.
arxiv +1 more source
Acupuncture randomized trials (ART) in patients with chronic low back pain and osteoarthritis of the knee - Design and protocols [PDF]
, 2003 Background: We report on the study design and protocols of two randomized controlled trials (Acupuncture Randomized Trials = ART) that investigate the efficacy of acupuncture in the treatment of chronic low back pain and osteoarthritis of the knee ...
Becker-Witt, C. +9 more
core +1 more source
Journal of Orthopaedic Surgery and Research, 2021 Background Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of osteoarthritis of the knee.
Kevin Ki-Wai Ho +5 more
doaj +1 more source
A new parenting-based group intervention for young anxious children: results of a randomized controlled trial [PDF]
, 2011 Objective Despite recent advances, there are still no interventions that have been developed for the specific treatment of young children who have anxiety disorders.
Cartwright-Hatton, Sam +12 more
core +1 more source
Hypertension in Pregnancy, 2017 Objective: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension.
Kathryn J. Sharma +2 more
doaj +1 more source
A matching design for augmenting a randomized clinical trial with external control [PDF]
arXiv, 2022 The use of information from real world to assess the effectiveness of medical products is becoming increasingly popular and more acceptable by regulatory agencies. According to a strategic real-world evidence framework published by U.S. Food and Drug Administration, a hybrid randomized controlled trial that augments internal control arm with real-world
arxiv
A randomized trial of an Asthma Internet Self-management Intervention (RAISIN): study protocol for a randomized controlled trial [PDF]
, 2014 <b>Background</b><p></p> The financial costs associated with asthma care continue to increase while care remains suboptimal. Promoting optimal self-management, including the use of asthma action plans, along with regular health ...
Agur, Karolina +7 more
core +1 more source
Electroacupuncture Treatment for Women with Primary Obesity: A Review of Randomized Controlled Trials [PDF]
Journal of Acupuncture Research, 2020 The purpose of this review was to evaluate the effectiveness of electroacupuncture treatment for women with “primary obesity.” Primary obesity is caused by an imbalance in energy intake and consumption due to abnormal eating and living habits in the ...
Soo Jin Lee +9 more
doaj +1 more source