Results 21 to 30 of about 836,047 (311)

Protocol for a randomized controlled trial on community education and surveillance on antibiotics use among young children in Nepal

open access: yesContemporary Clinical Trials Communications, 2023
Background: Antimicrobial resistance (AMR) is one of the top ten threats to global health. There exists limited empirical evidence on effective approaches to address this threat.
Prajwol Nepal   +9 more
doaj   +1 more source

Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]

open access: yes, 2008
This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Norton, C.   +2 more
core   +1 more source

Identifying alternative mental health interventions: a systematic review of randomized controlled trials of chanting and breathwork

open access: yes, 2022
This systematic review of randomized controlled trials investigated the effects of two religious/spiritual (R/S) practices (breathwork and chanting) on mental health outcomes (depression, anxiety, stress, and post-traumatic stress disorder (PTSD ...
Meredith, Pamela   +3 more
core   +1 more source

Factors influencing the enrollment in randomized controlled trials in orthopedics

open access: yesContemporary Clinical Trials Communications, 2017
Background: Low enrollment rates are a threat to the external validity of clinical trials. The purpose of this study was to identify factors associated with lower enrollment rates in randomized controlled trials (RCTs) involving orthopedic procedures ...
Christopher T. Lim   +4 more
doaj   +1 more source

Dermatology and Randomized Control Trials

open access: yesIndian Dermatology Online Journal, 2021
Well-designed and rigorously conducted randomized controlled trial (RCT) can produce most valid and precise scientific evidence. Any intervention, be it systemic or topical medicine, dermatology procedure needs to be tested for its efficacy in improving particular disease condition and RCT should come into mind of investigator.
Patel, Nayankumar, Sil, Amrita
openaire   +2 more sources

Analysis of the characteristics and the degree of pragmatism exhibited by pragmatic-labelled trials of antineoplastic treatments

open access: yesBMC Medical Research Methodology, 2023
Background Pragmatic clinical trials (PCTs) are designed to reflect how an investigational treatment would be applied in clinical practice. As such, unlike their explanatory counterparts, they measure therapeutic effectiveness and are capable of ...
Robbe Saesen   +6 more
doaj   +1 more source

Visual data: a new tool to improve the presentation of clinical trial results

open access: yesEinstein (São Paulo), 2019
Randomized controlled trials are known to be the best tool to determine the effects of an intervention; however, most healthcare professionals are not able to adequately understand the results.
Raphael Mendes Ritti-Dias   +2 more
doaj   +2 more sources

Cost-effectiveness of telehealth-delivered nutrition interventions: a systematic review of randomized controlled trials [PDF]

open access: yes, 2023
CONTEXT: Telehealth-delivered nutrition interventions are effective in practice; however, limited evidence exists regarding their cost-effectiveness.OBJECTIVE: To evaluate the cost-effectiveness of telehealth-delivered nutrition interventions for ...
Campbell, Katrina L   +7 more
core   +1 more source

Interpreting Randomized Controlled Trials

open access: yesCancers, 2023
This article describes rationales and limitations for making inferences based on data from randomized controlled trials (RCTs). We argue that obtaining a representative random sample from a patient population is impossible for a clinical trial because patients are accrued sequentially over time and thus comprise a convenience sample, subject only to ...
Pavlos Msaouel, Juhee Lee, Peter F Thall
openaire   +2 more sources

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression

open access: yesBMC Medicine, 2012
Background Randomized, double-blind, placebo-controlled trials constitute the gold standard in clinical research when testing the efficacy of new psychopharmacological interventions in the treatment of major depression.
Severus Emanuel   +9 more
doaj   +1 more source

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