The external validity of published randomized controlled trials in primary care [PDF]
, 2009 Background - A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population.
Jones Robert O +29 more
core +2 more sources
Korean translation of the CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials [PDF]
Epidemiology and Health, 2014 The Consolidated Standards of Reporting Trials (CONSORT) 2010 Statement, updated in March 2010, includes a 25-item checklist and flow diagram. Adherence to this statement is a minimum requirement for the complete, clear, and transparent reporting of ...
Jun Suh Lee +3 more
doaj +1 more source
Three controlled trials of interventions to increase recruitment to a randomized controlled trial of mobile phone based smoking cessation support. [PDF]
, 2010 BACKGROUND: Recruitment is a major challenge for trials but there is little evidence regarding interventions to increase trial recruitment. We report three controlled trials of interventions to increase recruitment to the Txt2stop trial.
Free, Caroline +3 more
core +1 more source
Canadian Journal of Pain, 2019 Background: Electronic data collection is increasingly available as a means to collect pain-related clinical trial data; however, effectiveness and costs relative to traditional data collection are uncertain.
James S. Khan +10 more
doaj +1 more source
Does taking vitamin, mineral and fatty acid supplements prevent cognitive decline? A systematic review of randomized controlled trials [PDF]
, 2008 Background Observational studies have shown associations between nutritional status and cognition in later life but evidence from intervention studies is unclear.
McNeill, G, Jia, X, Avenell, Alison
core +2 more sources
BMC Cancer, 2017 Background Case reports, retrospective analyses, and observational studies have linked the use of cisplatin to increased risk of second cancers, especially life-threatening secondary leukemia.
Fei Liang +3 more
doaj +1 more source
Dermatology and Randomized Control Trials
Indian Dermatology Online Journal, 2021 Well-designed and rigorously conducted randomized controlled trial (RCT) can produce most valid and precise scientific evidence. Any intervention, be it systemic or topical medicine, dermatology procedure needs to be tested for its efficacy in improving particular disease condition and RCT should come into mind of investigator.
Patel, Nayankumar, Sil, Amrita
openaire +2 more sources
Efficacy of modern antipsychotics in placebo-controlled trials in bipolar depression: a meta-analysis – results to be interpreted with caution [PDF]
, 2010 Randomized, controlled trials have demonstrated efficacy for second-generation antipsychotics in the treatment of acute mania in bipolar disorder. Despite depression being considered the hallmark of bipolar disorder, there are no published systematic ...
Goikolea, José Manuel +7 more
core +1 more source
Beyond Randomized Controlled Trials
Journal of Evidence-Based Complementary & Alternative Medicine, 2012 Complementary and alternative medicine is criticized by some as lacking evidence to support the effectiveness of its methods and medicines. Such critics typically point to mixed results from using randomized controlled trials to test complementary and ...
Isaac Golden PhD
doaj +1 more source
Frequent fragility of randomized controlled trials for HCC treatment
BMC Cancer, 2021 Background The fragility index (FI) of trial results can provide a measure of confidence in the positive effects reported in randomized controlled trials (RCTs). The aim of this study was to calculate the FI of RCTs supporting HCC treatments.
Hao Zhang, Jingtao Li, Wenting Zeng
doaj +1 more source