Results 1 to 10 of about 340,610 (216)

What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco   +2 more
doaj   +1 more source

Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]

open access: yesInternational Brazilian Journal of Urology, 2023
Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves   +2 more
doaj   +1 more source

The effect FRIENDS program on the anxiety of adolescent girls

open access: yesSocial Determinants of Health, 2021
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer   +3 more
doaj   +1 more source

Non-inferiority trials

open access: yesPerspectives in Clinical Research, 2022
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan   +2 more
doaj   +1 more source

Equivalence trials

open access: yesPerspectives in Clinical Research, 2022
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan   +2 more
doaj   +1 more source

Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2022
Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon   +13 more
doaj   +1 more source

Topical vitamin D3: A randomized controlled trial (RCT) [PDF]

open access: yesClinical Nutrition ESPEN, 2018
The intent of this study was to test the effect of Top-D, a topical Vitamin D preparation, in delivering vitamin D.Five hundred and fifty healthy patients, with vitamin D insufficiency and deficiency were recruited after written informed consent. Demographic data was recorded, adequate history and clinical examination was done to rule out any metabolic
Dalal A, Bubshait   +2 more
openaire   +2 more sources

Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial [PDF]

open access: yesAnesthesia Progress, 2019
This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no ...
Nurain, Rehman, Samir Riaz, Qazi
openaire   +2 more sources

Topical Endoxifen for Mammographic Density Reduction—A Randomized Controlled Trial

open access: yesThe Oncologist, 2022
Abstract Although breast cancer incidence is increasing, there are few primary preventive initiatives. Tamoxifen can reduce breast cancer incidence but is rarely used for primary prevention due to adverse events and tolerance issues. We tested if endoxifen, a tamoxifen metabolite, applied directly to the skin of the breast, could reduce ...
Magnus Bäcklund   +8 more
openaire   +2 more sources

Effectiveness of Topic-specific Infobuttons: A Randomized Controlled Trial [PDF]

open access: yesJournal of the American Medical Informatics Association, 2008
Infobuttons are decision support tools that provide links within electronic medical record systems to relevant content in online information resources. The aim of infobuttons is to help clinicians promptly meet their information needs. The objective of this study was to determine whether infobutton links that direct to specific content topics ("topic ...
Guilherme, Del Fiol   +5 more
openaire   +2 more sources

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