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Randomized Controlled Trials on PET: A Systematic Review of Topics, Design, and Quality [PDF]

open access: bronzeJournal of Nuclear Medicine, 2012
Randomized controlled trials (RCTs) add important information to diagnostic accuracy studies in the evaluation of PET and PET/CT. We evaluated how many RCTs on PET existed, which clinical topics they addressed, and what their design and quality were.We searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials (Clinical Trials) up
Fülöp Scheibler   +8 more
semanticscholar   +5 more sources

Effectiveness of Topic-specific Infobuttons: A Randomized Controlled Trial [PDF]

open access: bronzeJournal of the American Medical Informatics Association, 2008
Infobuttons are decision support tools that provide links within electronic medical record systems to relevant content in online information resources. The aim of infobuttons is to help clinicians promptly meet their information needs. The objective of this study was to determine whether infobutton links that direct to specific content topics ("topic ...
Guilherme Del Fiol   +5 more
openalex   +4 more sources

Mechanical Low Back Pain: Secular Trend and Intervention Topics of Randomized Controlled Trials [PDF]

open access: greenPhysiotherapy Canada, 2015
Purpose: To evaluate the number of published randomized controlled trials (RCTs) focusing on mechanical low back pain (MLBP) rehabilitation, the secular (i.e., long-term) trend, and the distribution of interventions studied. Methods: All included RCTs were extracted from all Cochrane systematic reviews focusing on rehabilitation therapies for MLBP ...
Greta Castellini   +4 more
openalex   +7 more sources

TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC trial): study protocol for a randomized controlled trial [PDF]

open access: goldBMC Cancer, 2016
Cervical intraepithelial neoplasia (CIN) is the premalignant condition of cervical cancer. Whereas not all high grade CIN lesions progress to cervical cancer, the natural history and risk of progression of individual lesions remain unpredictable.
Margot M. Koeneman   +12 more
openalex   +8 more sources

TOPical Imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia (TOPIC-2 trial): a study protocol for a randomized controlled trial [PDF]

open access: goldBMC Cancer, 2018
Cervical dysplasia (cervical intraepithelial neoplasia (CIN)) is caused by Human Papillomavirus (HPV) and is most common in women of reproductive age. Current treatment of moderate to severe CIN is surgical. This procedure has potential complications, such as haemorrhage, infection and preterm birth in subsequent pregnancies.
Anna J. M. van de Sande   +5 more
openalex   +6 more sources

What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco   +2 more
doaj   +1 more source

Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]

open access: yesInternational Brazilian Journal of Urology, 2023
Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves   +2 more
doaj   +1 more source

Non-inferiority trials

open access: yesPerspectives in Clinical Research, 2022
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan   +2 more
doaj   +1 more source

The effect FRIENDS program on the anxiety of adolescent girls

open access: yesSocial Determinants of Health, 2021
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer   +3 more
doaj   +1 more source

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