Results 1 to 10 of about 337,732 (285)

Topical treatment of tungiasis: a randomized, controlled trial

Annals of Tropical Medicine & Parasitology, 2003
Tungiasis is caused by the penetration of the female sand flea Tunga penetrans into the epidermis of its host. Human infestation with this ectoparasite is hyper-endemic in many resource-poor communities in sub-Saharan Africa, the Caribbean and South America and is associated with considerable morbidity.
J, Heukelbach, M, Eisele, A, Jackson, H, Feldmeier   +3 more
openaire   +2 more sources

A Randomized, Placebo-Controlled Trial of Topical Retinol in the Treatment of Cellulite

American Journal of Clinical Dermatology, 2000
Cellulite occurs to varying degrees on the thighs and buttocks of many otherwise healthy women. Among the many purported treatments for cellulite, only a handful have been tested in clinical trials.The aim of this study was to critically explore the reputed effect of topical retinol in the treatment of cellulite.The study compared the effect of topical
C, Piérard-Franchimont, G E, Piérard, F, Henry, V, Vroome, G, Cauwenbergh   +4 more
openaire   +2 more sources

The Effects of Topical Ketorolac and Indomethacin on Measles Conjunctivitis: Randomized Controlled Trial

American Journal of Ophthalmology, 2006
To compare the effect of topical ketorolac and indomethacin on measles conjunctivitis.Prospective double-masked placebo-controlled randomized trial.Sixty-two patients with severe measles conjunctivitis were included in this study. All patients were hospitalized and randomly assigned to receive ketorolac 0.5% or indomethacin 0.1% in the right eye and ...
Toker, MI, Erdem, H, Erdogan, H, Arici, MK, Topalkara, A, Arslan, OS, Pahsa, A   +6 more
openaire   +4 more sources

Topical Nifedipine for the Treatment of Pressure Ulcer: A Randomized, Placebo-Controlled Clinical Trial

American Journal of Therapeutics, 2021
Background: Effect of nifedipine on pressure ulcer (PU) healing has not been evaluated in the human subjects yet. Study question: In this study, the effect of topical application of nifedipine 3% ointment on PU healing in critically ill patients was investigated.
Hedieh, Zolfagharnezhad, Hossein, Khalili, Mostafa, Mohammadi, Somayeh, Niknam, Alireza, Vatanara   +4 more
openaire   +2 more sources

A Randomized Controlled Trial of Topical Analgesia Posthemorrhoidectomy (TAPH Trial)

Diseases of the Colon & Rectum
BACKGROUND: Postoperative pain remains the greatest problem after hemorrhoidectomy. Pain is hypothesized to arise from bacterial infection, sphincter spasm, and local inflammation. OBJECTIVE: This trial was conducted to assess the effects of metronidazole, diltiazem, and lidocaine ...
James Z, Jin, Weisi, Xia, Runzhe, Gao, Alain C, Vandal, Maree, Weston, Lincoln, Israel, Andrew, Connolly, Primal Parry, Singh, Darren, Svirskis, Andrew, Hill   +9 more
openaire   +2 more sources

Topical Cyclosporin A in the treatment of acute graft rejection: a randomized controlled trial

Clinical & Experimental Ophthalmology, 2008
AbstractBackground:  Corneal graft rejection is the commonest cause of graft failure. Currently, intensive topical steroid is the treatment for graft rejection. We hypothesized that the use of topical Cyclosporin A (CsA) 0.05%, specifically Restasis (Allergan) in addition to intensive steroids would aid in the reversal and treatment of endothelial ...
Alexander, Poon, Marios, Constantinou, Ecosse, Lamoureux, Hugh R, Taylor   +3 more
openaire   +2 more sources

Topical Tranexamic Acid in Breast Reconstruction: A Double-Blind Randomized Controlled Trial

Plastic & Reconstructive Surgery, 2023
Background: Excess fluid accumulation (seroma/hematoma) around the breast implant after reconstruction can lead to significant complications. Topical administration of tranexamic acid (TXA) may reduce fluid accumulation and reduce postoperative complications. This trial aims to investigate whether TXA-treated mastectomy pockets
Tyler, Safran, Joshua, Vorstenbosch, Alex, Viezel-Mathieu, Peter, Davison, Tassos, Dionisopoulos   +4 more
openaire   +2 more sources

A Randomized Vehicle-Controlled Trial of Topical Capsaicin in the Treatment of Postherpetic Neuralgia

Survey of Anesthesiology, 1994
A large double-blind, vehicle-controlled study of 143 patients with chronic postherpetic neuralgia (PHN) was performed to evaluate the degree of efficacy of topically applied capsaicin 0.075% cream. In addition, the safety and efficacy of long-term application of topical capsaicin in PHN was assessed by following patients in an open-label study for up ...
C P, Watson, K L, Tyler, D R, Bickers, L E, Millikan, S, Smith, E, Coleman   +5 more
openaire   +2 more sources

Topical cyclosporin in oral lichen planus: a controlled, randomized, prospective trial

British Journal of Dermatology, 2006
The published studies of topical cyclosporin (CyA) therapy in chronic oral lichen planus (OLP) have shown conflicting results. We report an investigator-blinded study of 13 patients with OLP, who were randomly assigned to treatment with CyA (500 mg as a swish-and-spit medication for 5 min three times daily) or a corticosteroid oral paste (triamcinolone
P, Sieg, H, Von Domarus, V, Von Zitzewitz, H, Iven, L, Färber   +4 more
openaire   +2 more sources

A Randomized Controlled Trial of Topical Cannabidiol for the Treatment of Thumb Basal Joint Arthritis

The Journal of Hand Surgery, 2022
Since the passage of the Agricultural Improvement Act of 2018, hand surgeons have increasingly encountered patients seeking counseling on over-the-counter, topical cannabidiol (CBD) for the treatment of pain. To this end, we designed a human clinical trial to investigate the therapeutic potential of CBD for the treatment of pain associated with thumb ...
John T, Heineman, Grace L, Forster, Kristen L, Stephens, Patrick S, Cottler, Michael P, Timko, Brent R, DeGeorge   +5 more
openaire   +2 more sources