Results 1 to 10 of about 176,739 (297)

What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco   +2 more
doaj   +1 more source

Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]

open access: yesInternational Brazilian Journal of Urology, 2023
Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves   +2 more
doaj   +1 more source

The effect FRIENDS program on the anxiety of adolescent girls

open access: yesSocial Determinants of Health, 2021
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer   +3 more
doaj   +1 more source

Non-inferiority trials

open access: yesPerspectives in Clinical Research, 2022
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan   +2 more
doaj   +1 more source

Equivalence trials

open access: yesPerspectives in Clinical Research, 2022
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan   +2 more
doaj   +1 more source

Topical Lidocaine plus Diclofenac as a Local Anesthetic Agent in Central Venous Catheterization; a Randomized Controlled Clinical Trial.

open access: yesArchives of academic emergency medicine, 2021
Various methods of analgesia can be used to reduce or prevent procedural pain in emergency department (ED). This study aimed to evaluate the effectiveness of topical lidocaine-diclofenac combination compared to lidocaine-prilocaine combination (Xyla-P) in reduction of the pain during central venous catheter (CVC) insertion.In this randomized clinical ...
Azizkhani, Reza   +4 more
openaire   +3 more sources

Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2022
Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon   +13 more
doaj   +1 more source

Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments

open access: yesClinical Hypertension, 2022
Background Hypertension is an urgent public health problem. Consistent summary from natural and quasi-experiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current literature.
Tong Xia, Fan Zhao, Roch A. Nianogo
doaj   +1 more source

Visual data: a new tool to improve the presentation of clinical trial results

open access: yesEinstein (São Paulo), 2019
Randomized controlled trials are known to be the best tool to determine the effects of an intervention; however, most healthcare professionals are not able to adequately understand the results.
Raphael Mendes Ritti-Dias   +2 more
doaj   +2 more sources

Breast milk as a topical eye drop reduces the severity of ROP: A randomized placebo-controlled trial.

open access: yes, 2022
Abstract Objective Retinopathy of prematurity (ROP) is the most common cause of visual impairment and disability in preterm infants. Human breast milk contains stem cells which have the ability to differentiate into all three germ layers. This study investigated whether breast milk used as an eye drop reduces severe ROP or laser-requiring ROP ...
Musa Silahli   +9 more
openaire   +1 more source

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