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Randomized Controlled Trials on PET: A Systematic Review of Topics, Design, and Quality [PDF]

open access: yesJournal of Nuclear Medicine, 2012
Randomized controlled trials (RCTs) add important information to diagnostic accuracy studies in the evaluation of PET and PET/CT. We evaluated how many RCTs on PET existed, which clinical topics they addressed, and what their design and quality were.We searched MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials (Clinical Trials) up
F. Scheibler   +8 more
semanticscholar   +3 more sources

What is an “ongoing” clinical trial? An analysis of different sources revealed heterogeneous definitions of when a clinical trial starts and ends: a meta-research study [PDF]

open access: yesSão Paulo Medical Journal, 2023
BACKGROUND: Although the concept of an “ongoing study” seems self-explanatory, it is difficult to determine whether a trial is underway. OBJECTIVE: To analyze the definitions of “ongoing clinical trial” across different clinical trial registries ...
Rafael Leite Pacheco   +2 more
doaj   +1 more source

Low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction – a narrative review [PDF]

open access: yesInternational Brazilian Journal of Urology, 2023
Objectives: To provide an overview of low-intensity extracorporeal shockwave therapy (LIEST) for erectile dysfunction (ED), pointing out which concepts are already consolidated and which paths we still need to advance.
Rodrigo R. Vieiralves   +2 more
doaj   +1 more source

Effects of Core Training on Sport-Specific Performance of Athletes: A Meta-Analysis of Randomized Controlled Trials

open access: yesBehavioral Science, 2023
Improving athletes’ performance is a major topic of interest in studies on competitive sports. Core training has been used as a training method in daily life and rehabilitation, and recently, in competitive sports, with positive results.
K. Dong, Teng Yu, Buongo Chun
semanticscholar   +1 more source

The effect FRIENDS program on the anxiety of adolescent girls

open access: yesSocial Determinants of Health, 2021
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer   +3 more
doaj   +1 more source

Assessing and minimising risk of bias in randomized controlled trials of tobacco cessation interventions: Guidance from the Cochrane Tobacco Addiction Group.

open access: yesAddiction, 2023
The Cochrane Tobacco Addiction Group has created risk of bias tools which are topic-agnostic. In 2012 the Cochrane Tobacco Addiction Group created guidance specific to considerations for reviews of randomized controlled trials of tobacco cessation ...
J. Hartmann-Boyce, N. Lindson
semanticscholar   +1 more source

Non-inferiority trials

open access: yesPerspectives in Clinical Research, 2022
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan   +2 more
doaj   +1 more source

Celecoxib for Mood Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesJournal of Clinical Medicine, 2023
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory parameters have not yet been comprehensively evaluated. The aim of this study was to systematically summarize the available knowledge on this topic.
A. Gędek   +4 more
semanticscholar   +1 more source

Equivalence trials

open access: yesPerspectives in Clinical Research, 2022
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan   +2 more
doaj   +1 more source

Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials

open access: yesNutrients, 2022
Magnesium (Mg) may have several beneficial effects on human health outcomes. One hypothesized mechanism eliciting such effects is the action of Mg on serum inflammatory parameters. However, studies on this topic to date have several important limitations.
N. Veronese   +4 more
semanticscholar   +1 more source

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