Results 21 to 30 of about 176,739 (297)

Effectiveness of nursing intervention to reduce delirium in adult critically ill - A protocol for a randomized trial

Contemporary Clinical Trials Communications, 2023
The incidence of delirium in intensive care patients remains high, and its consequences have a high negative impact on patients, their families, health care teams, and society in general.
Luz Omaira Gómez Tovar, Ángela María Henao-Castaño   +1 more
doaj   +1 more source

Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial

Clinical Medicine Insights: Gastroenterology, 2014
Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE.
Salale, Nesrin, Treldal, Charlotte, Mogensen, Stine, Rasmussen, Mette, Petersen, Janne, Andersen, Ove, Jacobsen, Jette   +6 more
openaire   +5 more sources

Topical Lidocaine-ibuprofen versus Lidocaine-prilocaine as a Local Anesthetic Agent in Reducing Central Venous Catheter Insertion Pain: A Randomized Controlled Trial

Eurasian Journal of Emergency Medicine, 2022
Aim:This study was performed to evaluate the effectiveness of topical lidocaine-ibuprofen (LI) combination compared the lidocaine-prilocaine (LP) combination Xyla-P in the reduction of the pain during central venous catheter (CVC) insertion.Materials and Methods:In this randomized clinical trial, 100 adult patients requiring CVC insertion in the ...
Reza Azizkhani, Omid Ghayour Najafabadi, Farhad Heydari, Mina Saber, Sarah Mousavi   +4 more
openaire   +2 more sources

Darifenacin Versus Parasacral Transcutaneous Electric Nerve stimulation for overactive bladder syndrome in patients infected with Human T-Lymphotropic Virus 1 – randomized open clinical trial [PDF]

International Brazilian Journal of Urology
Purpose: To evaluate the efficacy of parasacral transcutaneous electric nerve stimulation (PTENS), in comparison to darifenacin for the reduction of OAB symptoms in patients infected with HTLV-1.
Tatiane Souza Soares de Oliveira, José Abraão C. Neto, Cassius José Vitor Oliveira, Néviton M. Castro, Edgar M. Carvalho   +4 more
doaj   +1 more source

The Effect of Schroth Therapy on Thoracic Kyphotic Curve and Quality of Life in Scheuermann’s Patients: A Randomized Controlled Trial [PDF]

Asian Spine Journal, 2019
Study Design Randomized controlled single-blinded clinical trial. Purpose To evaluate the efficacy of Schroth therapy on thoracic curve angle, pain, and self-perceived body image (SPBI) of the back in Scheuermann’s patients in comparison with the ...
Tomer Bezalel, Eli Carmeli, Dror Levi, Leonid Kalichman   +3 more
doaj   +1 more source

Reanalysis of a Randomized Controlled Trial on Promoting Influenza Vaccination in General Practice Waiting Rooms: A Zelen Design

Vaccines, 2022
In 2014–2015, we conducted a randomized controlled trial (RCT) assessing the effect of an advertising campaign for influenza vaccination using posters and pamphlets in general practitioner (GP) waiting rooms.
Christophe Berkhout, Jeroen De Man, Claire Collins, Amy Willefert-Bouche, Suzanna Zgorska-Maynard Moussa, Margot Badelon, Lieve Peremans, Paul Van Royen   +7 more
doaj   +1 more source

Topical platelet‐rich plasma as a possible treatment for olfactory dysfunction—A randomized controlled trial

International Forum of Allergy & Rhinology
AbstractBackgroundOlfactory dysfunction (OD) affects many survivors of COVID‐19. Prior studies have investigated the use of platelet‐rich plasma (PRP) injections for OD. We describe the first randomized controlled trial investigating topical PRP for OD treatment and contribute to existing literature illustrating PRP as an emerging therapeutic ...
Alexander Duffy, Bita Naimi, Emily Garvey, Stephanie Hunter, Ayan Kumar, Chase Kahn, Douglas Farquhar, Glen D'Souza, Nancy Rawson, Pamela Dalton, Elina Toskala, Mindy Rabinowitz, Marc Rosen, Gurston Nyquist, David Rosen   +14 more
openaire   +2 more sources

A capability framework to inform the fundamental requirements for clinical trial unit development, growth and long term success in outer metropolitan and rural areas

Contemporary Clinical Trials Communications, 2023
Background: Participation in clinical trials is linked to improved patient outcomes. Despite this, most trial participants either reside in, or are treated in metropolitan areas.
Anne Woollett, Jhodie Duncan, Mark Voskoboynik, Mark Shackleton, Michael Dooley, Robert Blum, Narelle McPhee, Tricia Wright, Zee Wan Wong, Jacqueline Dixon, Stephen M. Jane   +10 more
doaj   +1 more source

Topical Rapamycin as a Treatment for Fibrofolliculomas in Birt-Hogg-Dubé Syndrome: A Double-Blind Placebo-Controlled Randomized Split-Face Trial

PLoS ONE, 2014
Birt-Hogg-Dubé syndrome (BHD) is a rare autosomal dominant disorder characterised by the occurrence of benign, mostly facial, skin tumours called fibrofolliculomas, multiple lung cysts, spontaneous pneumothorax and an increased renal cancer risk. Current treatments for fibrofolliculomas have high rates of recurrence and carry a risk of complications ...
Gijezen, Lieke M. C., Vernooij, Marigje, Martens, Herm, Oduber, Charlene E. U., Henquet, Charles J. M., Starink, Theo M., Prins, Martin H., Menko, Fred H., Nelemans, Patty J., van Steensel, Maurice A. M.   +9 more
openaire   +7 more sources

Topical isoniazid as a novel treatment for melasma: A randomized, double‐blind, vehicle‐controlled clinical trial

Journal of Cosmetic Dermatology
AbstractIntroductionMelasma is a chronic hyperpigmentation disorder, and its treatment poses a challenge to dermatologists due to its chronicity and resistance to conventional therapies. Oral isoniazid is used for the treatment of tuberculosis. One of us had previously showed that topical isoniazid exerts a strong depigmenting action in animal models ...
Najmeh, Ahramiyanpour, Zahra, Mahmoudi, Nazanin Zeinali, Nezhad, Payam, Khazaeli, Rezvan, Amiri, Behrooz, Kasraee   +5 more
openaire   +2 more sources