Results 21 to 30 of about 337,732 (285)

Celecoxib for Mood Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesJournal of Clinical Medicine, 2023
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory parameters have not yet been comprehensively evaluated. The aim of this study was to systematically summarize the available knowledge on this topic.
Adam Gędek   +4 more
semanticscholar   +1 more source

Assessing and minimising risk of bias in randomized controlled trials of tobacco cessation interventions: Guidance from the Cochrane Tobacco Addiction Group.

open access: yesAddiction, 2023
The Cochrane Tobacco Addiction Group has created risk of bias tools which are topic-agnostic. In 2012 the Cochrane Tobacco Addiction Group created guidance specific to considerations for reviews of randomized controlled trials of tobacco cessation ...
J. Hartmann-Boyce, N. Lindson
semanticscholar   +1 more source

Non-inferiority trials

open access: yesPerspectives in Clinical Research, 2022
Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration.
Priya Ranganathan   +2 more
doaj   +1 more source

Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials

open access: yesNutrients, 2022
Magnesium (Mg) may have several beneficial effects on human health outcomes. One hypothesized mechanism eliciting such effects is the action of Mg on serum inflammatory parameters. However, studies on this topic to date have several important limitations.
N. Veronese   +4 more
semanticscholar   +1 more source

The effect FRIENDS program on the anxiety of adolescent girls

open access: yesSocial Determinants of Health, 2021
Background: Anxiety is one of the most common psychological problems among adolescents which have been almost considered by researchers. In this regard, the present study was conducted to examine the effect of the FRIENDS training program on the anxiety ...
Gholamreza Sanagooe Moharer   +3 more
doaj   +1 more source

β-Carotene Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesNutrients, 2022
β-carotene is widely available in plant-based foods, while the efficacy of β-carotene supplementation on cardiovascular disease (CVD) risk remains controversial. Hence, we performed a systematic review and meta-analysis on randomized controlled trials to
Jiaqi Yang, Yulin Zhang, X. Na, A. Zhao
semanticscholar   +1 more source

Equivalence trials

open access: yesPerspectives in Clinical Research, 2022
In an equivalence trial, researchers aim to show that a new intervention is more or less similar to an existing standard of care, i.e., the two are “equivalent”.
Priya Ranganathan   +2 more
doaj   +1 more source

School-based Mental Health Interventions Targeting Depression or Anxiety: A Meta-analysis of Rigorous Randomized Controlled Trials for School-aged Children and Adolescents

open access: yesJournal of Youth and Adolescence, 2022
Past meta-analyses in mental health interventions failed to use stringent inclusion criteria and diverse moderators, therefore, there is a need to employ more rigorous methods to provide evidence-based and updated results on this topic.
Qiyang Zhang   +2 more
semanticscholar   +1 more source

Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial [PDF]

open access: yesAnesthesia Progress, 2019
This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no ...
Nurain, Rehman, Samir Riaz, Qazi
openaire   +2 more sources

Topical vitamin D3: A randomized controlled trial (RCT) [PDF]

open access: yesClinical Nutrition ESPEN, 2018
The intent of this study was to test the effect of Top-D, a topical Vitamin D preparation, in delivering vitamin D.Five hundred and fifty healthy patients, with vitamin D insufficiency and deficiency were recruited after written informed consent. Demographic data was recorded, adequate history and clinical examination was done to rule out any metabolic
Dalal A, Bubshait   +2 more
openaire   +2 more sources

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