Results 31 to 40 of about 337,732 (285)

Topical Endoxifen for Mammographic Density Reduction—A Randomized Controlled Trial

The Oncologist, 2022
Abstract Although breast cancer incidence is increasing, there are few primary preventive initiatives. Tamoxifen can reduce breast cancer incidence but is rarely used for primary prevention due to adverse events and tolerance issues. We tested if endoxifen, a tamoxifen metabolite, applied directly to the skin of the breast, could reduce ...
Magnus Bäcklund, Mikael Eriksson, Marike Gabrielson, Mattias Hammarström, Steve Quay, Jenny Bergqvist, Roxanna Hellgren, Kamila Czene, Per Hall   +8 more
openaire   +2 more sources

Effect of L-carnitine on quality of life in covert hepatic encephalopathy: a randomized, double-blind, placebo-controlled study [PDF]

The Korean Journal of Internal Medicine, 2022
Background/Aims L-carnitine is potentially beneficial in patients with hepatic encephalopathy (HE). We aimed to evaluate the impact of L-carnitine on the quality of life and liver function in patients with liver cirrhosis and covert HE.
Eileen L. Yoon, Sang Bong Ahn, Dae Won Jun, Yong Kyun Cho, Do Seon Song, Jae Yoon Jeong, Hee Yeon Kim, Young Kul Jung, Myeong Jun Song, Sung Eun Kim, Hyoung Su Kim, Soung Won Jeong, Sang Gyune Kim, Tae Hee Lee   +13 more
doaj   +1 more source

The Optimal Strategy of Vitamin D for Sarcopenia: A Network Meta-Analysis of Randomized Controlled Trials

Nutrients, 2021
Sarcopenia is a disease of gradual loss of muscle mass in elderly people, and the most common treatment options include nutritional supplementation and exercise.
Shih-Hao Cheng, Kee-Hsin Chen, Chiehfeng Chen, W-C. Chu, Y. Kang   +4 more
semanticscholar   +1 more source

Intranasal Ketamine for Depression in Adults: A Systematic Review and Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials

Frontiers in Psychology, 2021
Background There is growing interest in glutamatergic agents as a treatment for depression, especially intranasal ketamine, which has become a hot topic in recent years.
Dongjiao An, Changwei Wei, Jing Wang, Anshi Wu   +3 more
semanticscholar   +1 more source

Efficacy of AST-120 for Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials

Frontiers in Pharmacology, 2021
AST-120, an oral spherical activated carbon, may delay the need for kidney dialysis and improve uremia symptoms because it can adsorb acidic and basic organic compounds, especially small-molecule uremic toxins.
Pei-Yu Su, Ya-Han Lee, L. Kuo, Yen‐Cheng Chen, Chiehfeng Chen, Y. Kang, E. H. Chang   +6 more
semanticscholar   +1 more source

Acupuncture for hot flashes: A literature review of randomized controlled trials conducted in the last 10 years

World Journal of Traditional Chinese Medicine, 2021
Objective: To conduct a literature review of randomized controlled trials (RCTs) on the use of acupuncture for hot flashes to analyze the characteristics of each study, draw a conclusion on the advantages and disadvantages of previous studies and provide
Ru-ya Sheng, Yan Yan, Hai Linh Dang
semanticscholar   +1 more source

Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials

International Journal of Women’s Dermatology, 2022
Background:Aging, an inevitable and continuous process in one’s lifetime, has all along been a focus of interest, especially for women, yet photoaging treatment to slow the process remains challenging. Recent studies have demonstrated the potency of topical tretinoin in the treatment of photoaging.
Irma Bernadette S. Sitohang, MD, PhD, Wresti Indriatmi Makes, MD, PhD, Normalina Sandora, MD, PhD, Jose Suryanegara, MD   +3 more
openaire   +3 more sources

Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments

Clinical Hypertension, 2022
Background Hypertension is an urgent public health problem. Consistent summary from natural and quasi-experiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current literature.
Tong Xia, Fan Zhao, Roch A. Nianogo
doaj   +1 more source

Minimally invasive versus open pancreatoduodenectomy for pancreatic and peri-ampullary neoplasm (DIPLOMA-2): study protocol for an international multicenter patient-blinded randomized controlled trial

Trials, 2023
Background Minimally invasive pancreatoduodenectomy (MIPD) aims to reduce the negative impact of surgery as compared to open pancreatoduodenectomy (OPD) and is increasingly becoming part of clinical practice for selected patients worldwide.
Nine Graaf, A. Emmen, M. Ramera, B. Björnsson, U. Boggi, C. Bruna, Olivier R. Busch, F. Daams, Giovanni Ferrari, S. Festen, J. Hilst, M. D'Hondt, B. Ielpo, T. Keck, I. Khatkov, B. Koerkamp, D. Lips, M. Luyer, J. Mieog, Luca Morelli, I. Molenaar, H. C. Santvoort, M. Sprangers, C. Ferrari, J. Berkhof, Patrick Maisonneuve, M. Abu Hilal, M. Besselink, for the Francophone Group for Enhanced Recovery After Surgery   +28 more
semanticscholar   +1 more source

Exercise Reduces Ambulatory Blood Pressure in Patients With Hypertension: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Although exercise training reduces office blood pressure (BP), scarcer evidence is available on whether these benefits also apply to ambulatory blood pressure (ABP), which is a stronger predictor of cardiovascular disease and mortality.
Gonzalo Saco-Ledo, P. Valenzuela, G. Ruiz‐Hurtado, L. Ruilope, A. Lucia   +4 more
semanticscholar   +1 more source