Results 31 to 40 of about 1,792,348 (283)

Interventions in hypertension: systematic review and meta-analysis of natural and quasi-experiments

Clinical Hypertension, 2022
Background Hypertension is an urgent public health problem. Consistent summary from natural and quasi-experiments employed to evaluate interventions that aim at preventing or controlling hypertension is lacking in the current literature.
Tong Xia, Fan Zhao, Roch A. Nianogo
doaj   +1 more source

Exercise Reduces Ambulatory Blood Pressure in Patients With Hypertension: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Although exercise training reduces office blood pressure (BP), scarcer evidence is available on whether these benefits also apply to ambulatory blood pressure (ABP), which is a stronger predictor of cardiovascular disease and mortality.
Gonzalo Saco-Ledo, P. Valenzuela, G. Ruiz‐Hurtado, L. Ruilope, A. Lucia   +4 more
semanticscholar   +1 more source

Minimally invasive versus open pancreatoduodenectomy for pancreatic and peri-ampullary neoplasm (DIPLOMA-2): study protocol for an international multicenter patient-blinded randomized controlled trial

Trials, 2023
Background Minimally invasive pancreatoduodenectomy (MIPD) aims to reduce the negative impact of surgery as compared to open pancreatoduodenectomy (OPD) and is increasingly becoming part of clinical practice for selected patients worldwide.
Nine Graaf, A. Emmen, M. Ramera, B. Björnsson, U. Boggi, C. Bruna, O. Busch, F. Daams, Giovanni Ferrari, S. Festen, J. Hilst, M. D'Hondt, Benedetto Ielpo, T. Keck, I. Khatkov, B. Koerkamp, D. Lips, M. Luyer, J. Mieog, Luca Morelli, I. Molenaar, H. C. Santvoort, M. Sprangers, C. Ferrari, Johannes Berkhof, Patrick Maisonneuve, M. Abu Hilal, M. Besselink, for the Francophone Group for Enhanced Recovery After Surgery   +28 more
semanticscholar   +1 more source

EVALUATION OF OUTCOMES IN INTERVENTION RANDOMIZED CLINICAL TRIALS - DISTAL RADIUS FRACTURES

Acta Ortopédica Brasileira, 2023
Objectives: Describe the frequency and types of outcomes in randomized clinical trials (RCT) of intervention for distal radius fractures, analyze how confusing outcome presentations can lead to misinterpretations, and suggest strategies to improve the ...
Davi Amorim Meira, Lukas Eiki Moriyama, Cássio Conceição Santana Santos, Fernando Delmonte Moreira, Alex Guedes, Enilton de Santana Ribeiro de Mattos   +5 more
doaj   +1 more source

Visual data: a new tool to improve the presentation of clinical trial results

Einstein (São Paulo), 2019
Randomized controlled trials are known to be the best tool to determine the effects of an intervention; however, most healthcare professionals are not able to adequately understand the results.
Raphael Mendes Ritti-Dias, Marilia de Almeida Correia, Breno Quintella Farah   +2 more
doaj   +2 more sources

Optimal allocation strategies in platform trials [PDF]

Statistical Methods in Medical Research, 2024, 2023
Platform trials are randomized clinical trials that allow simultaneous comparison of multiple interventions, usually against a common control. Arms to test experimental interventions may enter and leave the platform over time. This implies that the number of experimental intervention arms in the trial may change over time.
arxiv   +1 more source

Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy [PDF]

Pain, 2012
A length-dependent neuropathy with pain in the feet is a common complication of diabetes (painful diabetic neuropathy). It was hypothesized that pain may arise from sensitized-hyperactive cutaneous nociceptors, and that this abnormal signaling may be reduced by topical administration of the α(2)-adrenergic agonist, clonidine, to the painful area.
Claudia M. Campbell, Kerrie L. Brady, Mark S. Kipnes, Margaret Kelly, William K. Schmidt, Bruce C. Stouch, James N. Campbell, Karin L. Petersen, Karin L. Petersen, Michael C. Rowbotham, Michael C. Rowbotham   +10 more
openaire   +3 more sources

A quantitative and qualitative evaluation of reports of clinical trials published in six Brazilian dental journals indexed in the Scientific Electronic Library Online (SciELO)

Journal of Applied Oral Science, 2010
INTRODUCTION: Open access publishing is becoming increasingly popular within the biomedical sciences. SciELO, the Scientific Electronic Library Online, is a digital library covering a selected collection of Brazilian scientific journals many of which ...
Raphael Freitas de Souza, Carolina de Andrade Lima Chaves, Mona Nasser, Zbys Fedorowicz   +3 more
doaj   +1 more source

Investigator initiated trials versus industry sponsored trials - translation of randomized controlled trials into clinical practice (IMPACT)

BMC Medical Research Methodology, 2021
Background Healthcare decisions are ideally based on clinical trial results, published in study registries, as journal articles or summarized in secondary research articles.
Anette Blümle, Katharina Wollmann, Karin Bischoff, Philipp Kapp, Szimonetta Lohner, Edris Nury, Kai Nitschke, Jasmin Zähringer, Gerta Rücker, Martin Schumacher   +9 more
doaj   +1 more source

Age-related male hypogonadism and cognitive impairment in the elderly: Focus on the effects of testosterone replacement therapy on cognition [PDF]

, 2020
Background. Epidemiological data report that male hypogonadism may play a role in cognitive impairment in elderly. However, the effect of testosterone replacement therapy (TRT) on cognitive abilities in this cluster of patients has not been well ...
De Pergola G., De Tullio A., Giagulli V. A., Guastamacchia E., Lisco G., Triggiani V.   +5 more
core   +1 more source