Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Intratumoral dendritic cell immunotherapy controls dissemination of metastasis-initiating cancer cells, even in patients with metastatic breast cancer. [PDF]
Soyano A +12 more
europepmc +1 more source
Abstract Objectives This systematic review investigated the efficacy of biologic factors in the surgical treatment of periodontal suprabony defects. Materials and Methods Three databases were searched to identify RCTs comparing open‐flap debridement (OFD) combined with biologic factors only, or combined with bone substitute, and/or barriers to the same
Carrie Chew +5 more
wiley +1 more source
Genomic analysis unlocks the potential of denosumab as a targeted therapy for Crohn's disease. [PDF]
Pranata R +15 more
europepmc +1 more source
Relationship between vitamin D deficiency and early implant failure and osseointegration
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron +8 more
wiley +1 more source
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Retraction: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. [PDF]
PLOS One Editors.
europepmc +1 more source
Wogonoside Modulates the Nrf2/SLC40A1 Signaling Axis to Combat Inflammatory Osteolysis
This study explores the potential of wogonoside, a flavonoid from Scutellaria baicalensis, for treating inflammatory osteolysis and provides compelling experimental evidence supporting its promise as a functional food ingredient to alleviate associated bone loss.
Siyuan Zhou +6 more
wiley +1 more source
Diabetic Charcot Neuroarthropathy: A Contemporary Review of Molecular and Genetic Markers. [PDF]
Narayan G, Panchbhavi VK.
europepmc +1 more source
Regulation of RANKL by biomechanical loading in fibrochondrocytes of meniscus
James Deschner +5 more
openalex +1 more source

