Results 1 to 10 of about 1,467,405 (183)

Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms [PDF]

Endocrinology and Metabolism, 2021
Background Assessing nuclear features is diagnostically challenging in the aspect of thyroid pathology. The aim of this study was to determine whether pathologists could distinguish BRAF-like and RAS-like nuclear features morphologically and identify ...
Chan Kwon Jung, Andrey Bychkov, Dong Eun Song, Jang-Hee Kim, Yun Zhu, Zhiyan Liu, Somboon Keelawat, Chiung-Ru Lai, Mitsuyoshi Hirokawa, Kaori Kameyama, Kennichi Kakudo   +10 more
doaj   +1 more source

Sphingomyelin metabolism underlies Ras excitability for efficient cell migration and chemotaxis

Cell Structure and Function, 2023
In eukaryotic motile cells, the active Ras (Ras-GTP)-enriched domain is generated in an asymmetric manner on the cell membrane through the excitable dynamics of an intracellular signaling network.
Da Young Shin, Hiroaki Takagi, Michio Hiroshima, Satomi Matsuoka, Masahiro Ueda   +4 more
doaj   +1 more source

C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis

Frontiers in Immunology, 2022
Phagocytosis, macropinocytosis, and G protein coupled receptor-mediated chemotaxis are Ras-regulated and actin-driven processes. The common regulator for Ras activity in these three processes remains unknown.
Xuehua Xu, Henderikus Pots, Bernd K. Gilsbach, Dustin Parsons, Douwe M. Veltman, Sharmila G. Ramachandra, Haoran Li, Arjan Kortholt, Tian Jin   +8 more
doaj   +1 more source

Analysis of Hydraulic Characteristics of Broad Crested Weir with Semicircle Control Section [PDF]

Engineering and Technology Journal, 2016
This study deals with evaluation ofthe hydraulic characteristics such as critical depth, and discharge coefficient of a broad crested weir with semi-circle control section extend across the full width of a laboratory channel.
Thabet mohammed abdulatif
doaj   +1 more source

The Molecular Basis of Gender Variations in Mortality Rates Associated With the Novel Coronavirus (COVID-19) Outbreak

Frontiers in Molecular Biosciences, 2021
Since the outbreak of the novel coronavirus disease (COVID-19) at the end of 2019, the clinical presentation of the disease showed a great heterogeneity with a diverse impact among different subpopulations.
Ibrahim Y. Hachim, Ibrahim Y. Hachim, Mahmood Y. Hachim, Iman Mamdouh Talaat, Iman Mamdouh Talaat, Iman Mamdouh Talaat, Vanessa M. López-Ozuna, Narjes Saheb Sharif-Askari, Saba Al Heialy, Rabih Halwani, Rabih Halwani, Rabih Halwani, Qutayba Hamid, Qutayba Hamid, Qutayba Hamid   +14 more
doaj   +1 more source

Co-culture of Ulva sp. and Dicentrarchus labrax in Recirculating Aquaculture System: effects on growth, retention of nutrients and fatty acid profile

Aquatic Living Resources, 2020
European sea bass and Ulva sp. were co-cultured in different tanks of an indoor Recirculating Aquaculture System (Ulva-RAS) with bacterial biofilter, in an effort to optimize the efficiency of the system and to further decrease the waste effluent.
Chatzoglou Evanthia, Kechagia Panorea, Tsopelakos Aristeidis, Miliou Helen   +3 more
doaj   +1 more source

Current status of the prognostic molecular markers in medullary thyroid carcinoma

Endocrine Connections, 2020
Medullary thyroid cancer (MTC) is a rare thyroid malignancy, which arises from parafollicular C-cells. It occurs in the hereditary or sporadic form. Hereditary type is a consequence of activation of the RET proto-oncogene by germline mutations, whereas ...
Malgorzata Oczko-Wojciechowska, Agnieszka Czarniecka, Tomasz Gawlik, Barbara Jarzab, Jolanta Krajewska   +4 more
doaj   +1 more source

Analysis of Binding Site Hot Spots on the Surface of Ras GTPase [PDF]

, 2011
We have recently discovered an allosteric switch in Ras, bringing an additional level of complexity to this GTPase whose mutants are involved in nearly 30% of cancers.
Buhrman, Greg, Kearney, Bradley M., Kovrigina, Elizaveta A., Kovriguine, Evgueni, Kozakov, Dima, Mattos, Carla, Napoleon, Raeanne, O\u27Connor, Casey, Vajda, Sandor, Zerbe, Brandon   +9 more
core   +2 more sources

Transient disappearance of RAS mutant clones in plasma: A counterintuitive clinical use of EGFR inhibitors in RAS mutant metastatic colorectal cancer [PDF]

, 2019
Genomic studies performed through liquid biopsies widely elucidated the evolutionary trajectory of RAS mutant clones under the selective pressure of EGFR inhibitors in patients with wild type RAS primary colorectal tumors. Similarly, the disappearance of
Belardinilli, Francesca, Cortesi, Enrico, Gazzaniga, Paola, Gelibter, ALAIN JONATHAN, Giannini, Giuseppe, Gradilone, Angela, Loreni, Flavia, Mahdavia, Yasaman, Nicolazzo, Chiara, Raimondi, Cristina   +9 more
core   +1 more source

Apparent nutrient utilization and metabolic growth rate of Nile tilapia, Oreochromis niloticus, cultured in recirculating aquaculture and biofloc systems

Open Agriculture, 2022
Recirculating aquaculture systems (RAS) and biofloc systems (BFS) have been considered eco-friendly aquaculture technologies in the last few decades. However, which system performs better has become a common question for fish farmers.
Amin Muhamad, Agustono Agustono, Ali Muhamad, Prayugo Prayugo, Hum Nurul Nadiah Mohd Firdaus   +4 more
doaj   +1 more source