Results 31 to 40 of about 359,204 (269)

Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease

open access: yesClinical and Experimental Hypertension, 2018
Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension.
Misbah Hussain, Fazli Rabbi Awan
doaj   +1 more source

The correlation between RAS and COVID-19, short review of the latest evidence

open access: yesИнфекция и иммунитет, 2019
Coronavirus SARS-CoV-2 is responsible for the Coronavirus disease (COVID-19) cause of the recent global pandemic, which is causing thousands of deaths worldwide and represents a health challenge with few precedents in human history.
F. Ferrara, A. Vitiello
doaj   +1 more source

Isolation of enterotoxigenic Staphylococcus aureus harboring seb gene and enteropathogenic Escherichia coli (serogroups O18, O114 and O125) from soft and hard artisanal cheeses in Egypt [PDF]

open access: yesOpen Veterinary Journal, 2020
Background: Soft and hard artisanal cheeses are regularly consumed in Egypt. These products are usually processed from raw milk which may harbor many pathogenic and spoilage microorganisms.
Ola Wagih Hegab   +2 more
doaj   +1 more source

PPARγ-activation increases intestinal M1 macrophages and mitigates formation of serrated adenomas in mutant KRAS mice

open access: yesOncoImmunology, 2018
To identify novel hubs for cancer immunotherapy, we generated C57BL/6J mice with concomitant deletion of the drugable transcription factor PPARγ and transgenic overexpression of the mutant KRASG12V oncogene in enterocytes.
Tobias Gutting   +12 more
doaj   +1 more source

Effect of addition of mineral salts to recirculating aquaculture system: evaluation of water quality, growth performance and some biochemical and immune indices of African cichlid (Labidochromis lividus) fish [PDF]

open access: yesبوم‌شناسی آبزیان, 2022
In the present study, the effects of startup and addition of ammonium chloride (NH4Cl) and sodium nitrite (NaNO2) salts for 4 weeks before fish stocking on efficiency of biofilter for removal of total ammonia nitrogen (TAN) from water, survival rate ...
Mehrdad Sarkheil   +2 more
doaj  

RAS and beyond: the many faces of the neurofibromatosis type 1 protein

open access: yesDisease Models & Mechanisms, 2022
Neurofibromatosis type 1 is a rare neurogenetic syndrome, characterized by pigmentary abnormalities, learning and social deficits, and a predisposition for benign and malignant tumor formation caused by germline mutations in the NF1 gene.
Corina Anastasaki   +2 more
doaj   +1 more source

Farnesylthiosalicylic Acid-Loaded Albumin Nanoparticle Alleviates Renal Fibrosis by Inhibiting Ras/Raf1/p38 Signaling Pathway

open access: yesInternational Journal of Nanomedicine, 2021
Hui Huang,1,2 Qinhui Liu,1 Ting Zhang,2 Jinhang Zhang,1,2 Jian Zhou,1,2 Xiandan Jing,2 Qin Tang,1 Cuiyuan Huang,1,2 Zijing Zhang,1 Yingnan Zhao,1,2 Guorong Zhang,1,2 Jiamin Yan,1,2 Yan Xia,1,2 Ying Xu,1,2 Jiahui Li,1,2 Yanping Li,1 Jinhan He1,2 ...
Huang H   +16 more
doaj  

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko   +5 more
wiley   +1 more source

RAS-mediated tumor stress adaptation and the targeting opportunities it presents

open access: yesDisease Models & Mechanisms, 2022
Cellular stress is known to function in synergistic cooperation with oncogenic mutations during tumorigenesis to drive cancer progression. Oncogenic RAS is a strong inducer of a variety of pro-tumorigenic cellular stresses, and also enhances the ability ...
Alexandra Redding   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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