Results 81 to 90 of about 5,986,284 (284)

Effects of resveratrol on the cell viability of RAW 264.7 macrophage cells.

, 2013
RAW 264.7 cells were treated with 1, 5, and 10 µM of resveratrol without LPS treatments or with 5 µg/ml LPS or with 1 µM wortmannin treatments for 24 h. RAW 264.7 cells viability was measured and expressed as mean ± SEM for three independent experiments.
Bin Liu (5899), Yuan-Li Chen (309131), Ying He (125930), Jun Sun (48981), Di Lu (216447), Yi Zong (309128), Zong-Ji Zhang (309132), Yi-Shu Deng (309129), Dong Zhan (309130), Jing Liu (38537), Lin Sun (105539)   +10 more
core   +1 more source

Immunomodulatory Effect of the Biofield Energy Treated Cell Growth Medium (DMEM) and FBS in Immune Cells (Murine Macrophage RAW 264.7) [PDF]

, 2018
The objective of the present study was to evaluate the immunomodulatory effect of Biofield Energy Treatment (The Trivedi Effect®) on Dulbecco’s Modified Eagle’s Medium (DMEM) and fetal bovine serum (FBS) in murine macrophage cells (RAW 264.7).
Jana, Snehasis, Trivedi, Mahendra Kumar, Trivedi, Dahryn, Mondal, Sambhu Charan, Branton, Alice, Nayak, Gopal   +5 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium

Molecules, 2020
Macrophage polarization has become increasingly important for the improvement of the biocompatibility of biomaterials. In this study, we coated Ti discs with phospholipids (phosphatidylserine/phosphatidylcholine [4:1 mole/mole]) by evaporating the ...
Hongxuan Quan, Yongjoon Kim, Lele Wu, Hee-Chul Park, Hyeong-Cheol Yang   +4 more
doaj   +1 more source

Cytotoxicity of bismuth nanoparticles in the murine macrophage cell line RAW 264.7

Journal of Materials Science: Materials in Medicine, 2020
A promising use of bismuth nanoparticles (BiNPs) for different biomedical applications leads to a search for the elucidation of their toxicity mechanisms, since toxicity studies are still at early stage. In the current study, cytotoxic effects of BiNPs produced by laser ablation in solution (LASiS) was investigated in the murine macrophage line RAW 264.
Jessica Zablocki da Luz, Thiago Neves Machado, Arandi Ginane Bezerra, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +4 more
openaire   +2 more sources

The release of microparticles by RAW 264.7 macrophage cells stimulated with TLR ligands [PDF]

Journal of Leukocyte Biology, 2010
Abstract TLR ligands induce microparticle release by macrophages and highlight the importance of nitric oxide. MPs are small membrane-bound particles that originate from activated and dying cells and mediate intercellular communication. Once released from cells, MPs can serve as novel signaling elements in innate immunity,
Julie, Gauley, David S, Pisetsky
openaire   +2 more sources

Internalization of CPP by RAW 264.7 cells.

, 2013
A, RAW 264.7 macrophage were seeded on coverslips and incubated with 100 µg/mL AlexaFluor488-labeled fetuin-A-containing synthetic CPP (green) in DMEM culture medium supplemented with 10% FBS for 30 minutes at 37°C, with (right-hand side panel) or ...
Eric Hanssen (349226), Stephen G. Holt (400521), Lawrence P. McMahon (400520), Edward R. Smith (400519)   +3 more
core   +1 more source