Results 111 to 120 of about 17,435 (223)

Evolving role of proton therapy in contemporary oncology

Cancer, Volume 132, Issue 20, 15 October 2026.
Abstract Proton therapy offers a distinct physical advantage over photon radiotherapy through the Bragg peak dose concentration in target with both lower integral dose and finite path length, and sharper penumbra as compared to photons, collectively reducing radiation exposure to surrounding normal tissues and potentially improving the therapeutic ...
Emily S. Lebow, Helen A. Shih
wiley   +1 more source

Incorporating Variable RBE in IMPT Optimization for Ependymoma [PDF]

PURPOSE: To study the dosimetric impact of incorporating variable relative biological effectiveness (RBE) of protons in optimizing intensity-modulated proton therapy (IMPT) treatment plans and to compare it with conventional constant RBE optimization and
Mohan, Radhe, Cao, Wenhua, Goudarzi, Hadis Moazami, Lim, Gino, Grosshans, David   +4 more
core   +1 more source

Neural network modelling of proton RBE values at predominant survival fractions of in vitro data

Scientific Reports
While a constant relative biological effectiveness (RBE) of 1.1 is applied in clinical proton therapy, longstanding clinical concern and in vitro evidence demonstrate a variable proton RBE.
Erlend Lyngholm, Armin Lühr, Liheng Tian, Camilla Hanquist Stokkevåg, Helge Henjum, Andreas Havsgård Handeland, Johannes Tjelta, Kristian Smeland Ytre-Hauge   +7 more
doaj   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

HCCC-9810 RBE ad-PTEN vs ad-GFP

, 2018
The gene expression profile of bortezomib-sensitive HCCC-9810 cells compared to bortezomib-insensitive RBE cells infected with PTEN ...
Jiang, T (via Mendeley Data), Jiang, Tian-YI   +1 more
core   +1 more source

Integrating microdosimetric in vitro RBE models for particle therapy into TOPAS MC using the MicrOdosimetry-based modeliNg for RBE ASsessment (MONAS) tool

Objective. In this paper, we present MONAS (MicrOdosimetry-based modelliNg for relative biological effectiveness (RBE) ASsessment) toolkit. MONAS is a TOPAS Monte Carlo extension, that combines simulations of microdosimetric distributions with ...
Missiaggia, Marta, La Tessa, Chiara, Cordoni, Francesco G., Scifoni, Emanuele, Cartechini, Giorgio   +4 more
core   +1 more source

Effects of Rice Bran Extract on the Quality and Digestive Properties of Chinese Steamed Buns

Foods
This study investigated the effects of rice bran extract (RBE) on the quality and digestibility of Chinese steamed buns (CSBs). RBE decreased the starch pasting properties, weakened the starch gel network structure, and reduced the storage modulus (G ...
Jing Liu, Zihan Zhang, Sichen Wang, Shiyi Lu, Haoran Fan, Hongyan Li, Jing Wang   +6 more
doaj   +1 more source

Evaluation of relative biological effectiveness of 225Ac and its decay daughters with Monte Carlo track structure simulations

EJNMMI Physics
Background 225Ac is a radionuclide that can be utilized in targeted alpha therapy (TAT). To accurately assess the absorbed dose and radiation effects in TAT, it is necessary to calculate the relative biological effectiveness (RBE).
Ziyi Hu, Shuiyin Qu, Hongming Liu, Yunhao Zhang, Shuchang Yan, Ankang Hu, Rui Qiu, Zhen Wu, Hui Zhang, Junli Li   +9 more
doaj   +1 more source

RBE Estimation of Proton Radiation Fields Using a DeltaE-E Telescope

, 2009
A new monolithic silicon DeltaE−E telescope was evaluated in unmodulated and modulated 100 MeV proton beams used for hadron therapy. Compared to a classical microdosimetry detector, which provides one-dimensional information on lineal energy of charged ...
A. Rosenfeld, R. Schulte, A. Wroe, GIULINI CASTIGLIONI AGOSTEO, STEFANO LUIGI MARIA, POLA, ANDREA, FAZZI, ALBERTO   +5 more
core   +1 more source

Evaluation of specific RBE in different cells of hippocampus under high-dose proton irradiation in rats

Scientific Reports
The study aimed to determine the specific relative biological effectiveness (RBE) of various cells in the hippocampus following proton irradiation. Sixty Sprague–Dawley rats were randomly allocated to 5 groups receiving 20 or 30 Gy of proton or photon ...
Shengying Zhou, Xingchen Ding, Yiyuan Zhang, Yuanyuan Liu, Xiaowen Wang, Yujiao Guo, Jianguang Zhang, Xiao Liu, Guanzhong Gong, Ya Su, Lizhen Wang, Miaoqing Zhao, Man Hu   +12 more
doaj   +1 more source