Results 71 to 80 of about 17,435 (223)
Precision Radiation Oncology, EarlyView.This study underscores the critical role of PTMs in mediating cellular responses to X‐ray and Carbon ion irradiation radiotherapy in HNSCC. The integration of multi‐omics data provides insights into the molecular mechanisms underlying radiation‐induced changes, offering valuable clues for improving therapeutic outcomes and advancing precision medicine ...
Fan‐Tong Xia +13 more
wiley +1 more source
RBE values obtained for the two proton radiation qualities.
, 2018 RBE values obtained for the two proton radiation qualities.
Emília Rita Szabó (5946305) +8 more
core +1 more source
Neuroprotective role of rice bran extract and its constituents in a neuroinflammatory mouse model
BMC Complementary Medicine and TherapiesBackground Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor known to play a critical role in regulating neuroinflammation and neurodegenerative processes, including Alzheimer’s disease.
Sarah M. Abou El-Nagah +3 more
doaj +1 more source
Advances in Radiation OncologyPurpose: To determine the relative biological effectiveness (RBE) in the rat spinal cord after 6 fractions of protons as a function of linear energy transfer (LET) and dose.
Christin Glowa, PhD +11 more
doaj +1 more source
Expert consensus on clinical trial design guidelines for FLASH radiotherapy
Precision Radiation Oncology, EarlyView.• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo +9 more
wiley +1 more source
Impact of DNA Repair Kinetics and Dose Rate on RBE Predictions in the UNIVERSE
, 2022 Accurate knowledge of the relative biological effectiveness (RBE) and its dependencies is crucial to support modern ion beam therapy and its further development.
Dokic, Ivana +15 more
core +1 more source
Toward a theory of Bayesian experimentation in early‐stage ventures
Strategic Entrepreneurship Journal, EarlyView.Abstract Research Summary The entrepreneurship literature has established the benefits of experimentation but has paid comparatively little attention to its costs. We develop a Bayesian model to illustrate the entrepreneurial choice between direct and experimental entry.
Andrea Contigiani +2 more
wiley +1 more source
Rat mammary carcinogenesis following neutron- or X-radiation [PDF]
, 1974 Female 61 to 63 - day - old Sprague-Dawley rats were exposed once to a single dose of either 0.43 - MeV neutrons or 250 - kVX - rays . For neutrons 23 rats were exposed in plastic tubes rotated around and 31 c m from a water-cooled tritium impregnated ...
Rossi, H. H. +8 more
core +1 more source
CircHECTD1 Promotes Cholangiocarcinoma Progression Through Interaction With SFPQ to Induce Autophagy
Cancer Science, EarlyView.CircHECTD1 directly interacts with SFPQ to upregulate ATG12 expression, thereby activating autophagy and promoting cholangiocarcinoma progression. This study uncovers a noncanonical circRNA–RNA‐binding protein regulatory mechanism and provides a potential therapeutic target for cholangiocarcinoma.
Shouwen Zhao +11 more
wiley +1 more source
, 2003 Eric J. Hallの教科書によると生物効果比(RBE)は以下のように定義されている。 \nある放射線(r)を250kVＸ線と比較した時のRBEは、250kVＸ線と放射線(r)とが同じ生物効果を生じるのに必要な線量をD250,Dr,とすると、その比D250/ Drによって表される。 \n HIMACで求めた最初のRBEは重粒子線治療の先駆けとして安藤らがマウス皮膚反応で求めた290MeV/u炭素線6cmSOBPの2.8という値である。 重粒子共同利用研究は ...
野島, 久美恵 +3 more
core