Results 31 to 40 of about 20,257 (224)
Adipocyte HSL is required for maintaining circulating vitamin A and RBP4 levels during fasting [PDF]
Vitamin A (retinol) is distributed via the blood bound to its specific carrier protein, retinol-binding protein 4 (RBP4). Retinol-loaded RBP4 is secreted into the circulation exclusively from hepatocytes, thereby mobilizing hepatic retinoid stores that ...
Julia S Steinhoff +21 more
openalex +2 more sources
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Backgrounds. Retinol-binding protein 4 (RBP4) is a monomeric-binding protein belonging to the lipocalin protein family, which has been reported to be dysregulated in several malignancies such as breast cancer and lung cancer.
Xinqing Deng +3 more
doaj +1 more source
Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model [PDF]
BackgroundPsoriasis is a common chronic inflammatory skin disease that features the abnormal proliferation of keratinocytes. This proliferation could partly result from disturbances in vitamin A metabolism.
Haimeng Wang +4 more
openalex +2 more sources
Objective The aim of this study is to investigate whether Serpin clade C (SERPINC1), E-selectin, P-selectin, Placental protein 13 (PP13), and Retinol-binding protein-4 (RBP4) levels in maternal serum were associated with the presence of preeclampsia and ...
R. M. Palalıoğlu, H. I. Erbıyık
semanticscholar +1 more source
There is a significant comorbidity between obesity and periodontitis, while adipokines are pivotal in the immunoinflammatory process, which may play a role in this special relationship.
Yuwei Zhang +4 more
semanticscholar +1 more source
Valosin-containing protein (VCP) is a versatile and ubiquitously expressed AAA+ ATPase that regulates multiple stages of Drosophila spermatogenesis. While VCP has documented roles in mitotic spermatogonia and meiotic spermatocytes, it is also highly ...
Tyler J. Butsch +2 more
semanticscholar +1 more source
Retinol binding protein-4 (RBP4) is a new adipokine synthesized by the liver and adipose tissue, and its secretion depends on retinol concentrations and reflects visceral fat mass.
Marwa Thaier Naji +6 more
doaj +1 more source
Elevated Serum Retinol Binding Protein 4 is Associated with the Risk of Diabetic Cardiomyopathy
Background: Retinol binding protein 4 (RBP4), a biomarker for insulin resistance in type 2 diabetes (DM), is increased in heart failure. This case-control study aims to determine the association between serum RBP4 levels and diabetic cardiomyopathy (DCM).
Haihua Shan +8 more
doaj +1 more source
Hepatocytes Are the Principal Source of Circulating RBP4 in Mice [PDF]
RBP4 is produced mainly by hepatocytes. In type 2 diabetes and obesity, circulating RBP4 is increased and may act systemically to cause insulin resistance and glucose intolerance. Observations that adipocyte RBP4 mRNA increases in parallel with circulating RBP4 in these conditions, whereas liver RBP4 mRNA does not, led to a widely held hypothesis that ...
S.J. Thompson +9 more
openalex +4 more sources

