Results 41 to 50 of about 20,257 (224)

Isoforms of Retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liver

Lipids in Health and Disease, 2008
Background The levels of retinol-binding protein 4 (RBP4) – the carrier protein for Vitamin A in plasma – are tightly regulated under healthy circumstances.
Weickert Martin O, Zidek Walter, Tepel Martin, Berg Thomas, Schlosser Beate, Raila Jens, Henze Andrea, Nagl Britta, Frey Simone K, Pfeiffer Andreas FH, Schweigert Florian J   +10 more
doaj   +1 more source

Dapagliflozin treatment and cardiovascular outcome in RBP4/TTRVal30Met (transthyretin cardiac amyloidosis) mice

ESC Heart Failure, 2023
Whether sodium‐glucose co‐transporter 2 inhibitors are effective for heart failure caused by ATTR‐CA (transthyretin cardiac amyloidosis) remains uncertain.
Zonglin Li, F. Lv, Xin Wen, Chengcheng Guo, Li Li, X. Cai, Chu Lin, Mengqing Zhang, Wenjia Yang, Linong Ji   +9 more
semanticscholar   +1 more source

The Effects of RBP4 and Vitamin D on the Proliferation and Migration of Vascular Smooth Muscle Cells via the JAK2/STAT3 Signaling Pathway

Oxidative Medicine and Cellular Longevity, 2022
Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) are one of the main causes of the development of diabetic atherosclerotic process.
Wan Zhou, Wei Wang, Xiaomin Yuan, Chunchun Xiao, Yan Xing, S. Ye, Qiang Liu   +6 more
semanticscholar   +1 more source

Significantly Reduced Retinol Binding Protein 4 (RBP4) Levels in Critically Ill COVID-19 Patients

Nutrients, 2022
The SARS-CoV-2 virus is the causative agent of the COVID-19 pandemic. The disease causes respiratory failure in some individuals accompanied by marked hyperinflammation. Vitamin A (syn. retinol) can exist in the body in the storage form as retinyl ester,
R. Vollenberg, Phil Tepasse, M. Fobker, A. Hüsing-Kabar   +3 more
semanticscholar   +1 more source

Waist Circumference was Positively Correlated with Chemerin, Retinol-Binding Protein 4 and hsCRP

Indonesian Biomedical Journal, 2012
BACKGROUND: Central obesity is associated with various chronic metabolic disorders characterized by abnormal cytokine production, increased acute phase reactants, and activation of inflammatory signaling pathways.
Lucia Herminawati, Anna Meiliana, Andi Wijaya   +2 more
doaj   +1 more source

Mapping of the extracellular RBP4 ligand binding domain on the RBPR2 receptor for Vitamin A transport

Frontiers in Cell and Developmental Biology, 2023
The distribution of dietary vitamin A/all-trans retinol/ROL throughout the body is critical for maintaining retinoid function in peripheral tissues and for retinoid delivery to the eye in the support of visual function.
Rakesh Radhakrishnan, Matthias Leung, Ashish K. Solanki, Glenn P. Lobo, Glenn P. Lobo, Glenn P. Lobo   +5 more
doaj   +1 more source

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

Investigative Opthalmology & Visual Science, 2017
Transgenic mice overexpressing serum retinol-binding protein (RBP4-Tg) develop progressive retinal degeneration, characterized by microglia activation, yet the precise mechanisms underlying retinal degeneration are unclear. Previous studies showed RBP4-Tg mice have normal ocular retinoid levels, suggesting that degeneration is independent of the ...
Du, Mei, Phelps, Eric, Balangue, Michael J., Dockins, Aaron, Moiseyev, Gennadiy, Shin, Younghwa, Kane, Shelley, Otalora, Laura, Ma, Jian-Xing, Farjo, Rafal, Farjo, Krysten M.   +10 more
openaire   +2 more sources

Effect of Upregulation of Transcription Factor TFDP1 Binding Promoter Activity Due to RBP4 g.36491960G>C Mutation on the Proliferation of Goat Granulosa Cells

Cells, 2022
Retinol-binding protein 4 (RBP4), a member of the lipocalin family, is a specific carrier of retinol (vitamin A) in the blood. Numerous studies have shown that RBP4 plays an important role in mammalian embryonic development and that mutations in RBP4 can
Yufang Liu, Siwu Guo, Xiaoyun He, Yanting Jiang, Q. Hong, R. Lan, M. Chu   +6 more
semanticscholar   +1 more source

Associations between retinol-binding protein 4 and cardiometabolic risk factors and subclinical atherosclerosis in recently postmenopausal women: cross-sectional analyses from the KEEPS study

Cardiovascular Diabetology, 2012
Background The published literature regarding the relationships between retinol-binding protein 4 (RBP4) and cardiometabolic risk factors and subclinical atherosclerosis is conflicting, likely due, in part, to limitations of frequently used RBP4 assays ...
Huang Gary, Wang Dan, Khan Unab I, Zeb Irfan, Manson JoAnn E, Miller Virginia, Hodis Howard N, Budoff Matthew J, Merriam George R, Harman Mitchell S, Brinton Eliot A, Cedars Marcelle I, Su Yali, Lobo Rogerio A, Naftolin Frederick, Santoro Nanette, Taylor Hugh S, Wildman Rachel P   +17 more
doaj   +1 more source

Altering retinol binding protein 4 levels in hepatitis C: Inflammation and steatosis matter

Virulence, 2020
Both hepatitis C virus (HCV) infection and retinol-binding protein 4 (RBP4) might contribute to insulin resistance (IR), how RBP4 links to IR in HCV infection remain elusive.
Ming-Ling Chang, Wei-Ting Chen, Jing-Hong Hu, Shiang-Chi Chen, Po-Wen Gu, Rong-Nan Chien   +5 more
doaj   +1 more source