Results 91 to 100 of about 53,016 (292)

Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update

Advanced Science, EarlyView.
This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari, James L. Grace, Jiajia Li, Joji Tanaka, Glen R. Jones, Athina Anastasaki, Wei You, Jian Zhu, Masami Kamigaito, Cyrille Boyer, Greg G. Qiao   +10 more
wiley   +1 more source

Mutations in RNA‐dependent RNA polymerase could be major cause of high pandemic potential of SARS‐CoV‐2: An in‐silico study

Indonesian Journal of Biotechnology
Human coronaviruses (HCoVs) are responsible for mild common cold to severe pneumonia‐like symptoms in infected individuals. The first HCoV was HCoV‐229E, discovered in 1962 in the US, which causes moderate symptoms.
Bhawna Sharma, Bennet Angel, Annette Angel, Vinod Joshi, Shareef Mohammed Buvvaji, Neha Singh, Khushbu Kumari, Aarya Chitransh, Poorna Khaneja, Devendra Kumar   +9 more
doaj   +1 more source

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A., Evans, D. J., Gould, E. A., Gritsun, T. S., Jones, I. M., Tuplin, A.   +5 more
core   +3 more sources

In silico study of natural compounds from sesame against COVID-19 by targeting Mpro, PLpro and RdRp

RSC Advances, 2021
Natural products and traditional medicine products with known safety profiles are a promising source for the discovery of new drug leads. Natural products as sesame were reported to exhibit potential to protect from COVID-19 disease.
Ahmed E. Allam, Yhiya Amen, A. Ashour, Hamdy K Assaf, H. Hassan, Islam M. Abdel-Rahman, A. Sayed, Kuniyoshi Shimizu   +7 more
semanticscholar   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

Evaluation of the Antiviral Characteristics of Tetragonula sapiens Propolis from Indonesia Using In Vitro and In Silico Methods

International Journal of Technology
The previous outbreaks of syndrome coronavirus 2 (SARS-CoV-2) are indications of the need for effective antiviral agents to mitigate disease severity and future outbreaks. In this context, natural products such as propolis have gained attention for their
Safira Candra Asih, Mohammad Nasikin, Jim-Tong Horng, Hui-Ping Tsai, Shan-Ko Tsai, Cheng-Hsun Chiu, Diah Kartika Pratami, Abdul Mun’im, Muhamad Sahlan   +8 more
doaj   +1 more source

Development of a method for evaluating the mRNA transcription activity of influenza virus RNA-dependent RNA polymerase through real-time reverse transcription polymerase chain reaction

Virology Journal, 2021
Background The development of an influenza RNA-dependent RNA polymerase (RdRp) inhibitor is required; therefore, a method for evaluating the activity of influenza RdRp needs to be developed.
Yuka Horio, Mototada Shichiri, Yuji Isegawa   +2 more
doaj   +1 more source

Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities [PDF]

, 2017
Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new ...
Coluccia, A., Famiglini, V., Hiscott, J., La Regina, G., Lee, J. C., Masci, D., Pelliccia, S., Silvestri, R., Tseng, C. K., Wub, Y. H.   +9 more
core   +1 more source

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

Macromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz, Cevin P. Braksch, Jonas De Breuck, Matthias Hartlieb, Meike N. Leiske   +4 more
wiley   +1 more source

Geographical and chronological origin and evolution of Hepatitis C Virus. [PDF]

, 2011
Hepatitis C Virus (HCV) infection is a major health problem that leads to cirrhosis and hepatocellular carcinoma. World over, more than 270-300 million people are estimated to be infected with the virus.
Achuthsankar S. Nair, amjesh revikumar, Sugunan V.S.   +2 more
core   +2 more sources