Results 81 to 90 of about 36,268 (188)

Development and deployment of a risk assessment index as a decision‐support tool for managing whitefly‐transmitted viruses affecting squash

open access: yesPest Management Science, EarlyView.
A data‐driven framework identified planting date and row cover as dominant drivers of whitefly‐transmitted virus complex (WTVC) risk in squash. Integration into the SquashRx mobile application enables real‐time risk assessment and supports improved decision‐making for integrated pest management.
Clarence B Codod   +9 more
wiley   +1 more source

Genotypes of NoVs based on RdRp and capsid genes.

open access: yes, 2014
Genotypes of NoVs based on RdRp and capsid genes.
Van Thai Than (562959)   +2 more
core   +1 more source

Interference of small compounds and Mg2+ with dsRNA-binding fluorophores compromises the identification of SARS-CoV-2 RdRp inhibitors

open access: yesScientific Reports
The COVID-19 pandemic highlighted the need for the rapid development of antiviral therapies. Viral RNA-dependent RNA polymerases (RdRp) are promising targets, and numerous virtual screenings for potential inhibitors were conducted without validation of ...
Susana Llanos   +5 more
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

NeoRdRp2 with improved seed data, annotations, and scoring

open access: yesFrontiers in Virology
RNA-dependent RNA polymerase (RdRp) is a marker gene for RNA viruses; thus, it is widely used to identify RNA viruses from metatranscriptome data. However, because of the high diversity of RdRp domains, it remains difficult to identify RNA viruses using ...
Shoichi Sakaguchi   +4 more
doaj   +1 more source

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

open access: yesAllergy, EarlyView.
Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal   +42 more
wiley   +1 more source

The percentage identity between the CP and RdRP proteins of ScPVs and CsPV1.

open access: yes, 2023
The percentage identity between the CP and RdRP proteins of ScPVs and CsPV1.
Ignacio de la Higuera (243161)   +11 more
core   +1 more source

Positive-Strand RNA Viral RdRps: From Structure Conservation and Activity Assay to Drug Development

open access: yesMolecules
Positive-strand RNA viruses represented by SARS-CoV-2 and DENV spread globally with high infectivity and frequent mutations, posing a severe threat to human health. However, specific and effective antiviral drugs remain limited.
Siyuan Zhao, Ziyu Lin, Minglian Wang
doaj   +1 more source

Molecular Evolutionary Analyses of the RNA-Dependent RNA Polymerase Region in Norovirus Genogroup II

open access: yesFrontiers in Microbiology, 2018
Noroviruses are the leading cause of viral gastroenteritis in humans across the world. RNA-dependent RNA polymerase (RdRp) plays a critical role in the replication of the viral genome.
Keita Ozaki   +9 more
doaj   +1 more source

Metagenomic detection and characterization of RNA viruses associated with Rhipicephalus linnaei (Audouin, 1826) ticks from the Amazon, Pará, Brazil

open access: yesMedical and Veterinary Entomology, EarlyView.
Metagenomic analysis of Rhipicephalus linnaei from the Brazilian Amazon revealed the presence of RNA viruses belonging to the families Chuviridae, Phenuiviridae, Orthomyxoviridae and Rhabdoviridae. This study reports the first detection of Brown dog tick mivirus 1 and Brown dog tick phlebovirus 2 in Brazil, based on genomic characterization and ...
Lucas Henrique da Silva e Silva   +13 more
wiley   +1 more source

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