Results 91 to 100 of about 46,334 (221)

Detection and Characterization of Cucumis melo Cryptic Virus, Cucumis melo Amalgavirus 1, and Melon Necrotic Spot Virus in Cucumis melo

Viruses, 2019
Three RNA viruses—Cucumis melo cryptic virus (CmCV), Cucumis melo amalgavirus 1 (CmAV1), and melon necrotic spot virus (MNSV)—were identified from a melon (Cucumis melo) transcriptome dataset.
Binhui Zhan, Mengji Cao, Kaina Wang, Xifeng Wang, Xueping Zhou   +4 more
doaj   +1 more source

Inhibitory effect of lupeol, quercetin, and solasodine on Rhizopus oryzae: A molecular docking and dynamic simulation study

Journal of Infection and Public Health, 2023
Background: Mucormycosis is an infection caused by fungi belonging to the order Mucorales. Rhizopus oryzae is one of the most prevalent organisms identified in mucormycosis patients.
Deepavalli Arumuganainar, Pradeep Kumar Yadalam, Khalid J. Alzahrani, Khalaf F. Alsharif, Fuad M. Alzahrani, Saleh Alshammeri, Sheik S.S.J. Ahmed, Thilla Sekar Vinothkumar, Hosam Ali Baeshen, Shankargouda Patil   +9 more
doaj   +1 more source

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, EarlyView.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Rituximab-Containing Treatment Regimens May Imply a Long-Term Risk for Difficult-To-Treat Chronic Hepatitis E [PDF]

, 2020
Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries which is usually characterized by a self-limited course. However, there is an increased risk of HEV persistence in immunocompromised risk populations, comprising ...
Biedermann, Paula, Bock, Claus-Thomas, Choi, Mira, Hanitsch, Leif Gunnar, Hofmann, Jörg, Mueller, Tobias, Schulz, Marten, Tacke, Frank   +7 more
core   +1 more source

Ebola Virus L Polymerase RdRp Sequence and Phylogenetic Analysis [PDF]

Egyptian Journal of Biomedical Engineering and Biophysics, 2019
Ebola Virus (EBOV) infection affects humans beings in the last four decades with the deadliest outbreak at 2015 in West Africa, leaving more than 10,000 deaths. The virus harms the liver of the patient when direct contact with contaminated body fluids or blood is occurred.
Mohamed El gohary, Amir Eissa, Abdo Elfiky, Amr Desouky   +3 more
openaire   +1 more source

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

Macromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz, Cevin P. Braksch, Jonas De Breuck, Matthias Hartlieb, Meike N. Leiske   +4 more
wiley   +1 more source

Molecular studies on the sweet potato virus disease and its two causal agents [PDF]

, 2002
The studies presented in this thesis contribute to an increased understanding of the molecular aspects, variability and interaction of the two most important viral pathogens of sweet potato (Ipomoea batatas L): Sweet potato feathery mottle virus (SPFMV ...
Kreuze, Jan
core  

Arsonic Acid Functional Polymers Enable Stabilization of Iron Oxide Nanoparticles in Aqueous Solution

Macromolecular Rapid Communications, EarlyView.
Arsonic acid containing diblock copolymers are developed to incorporate arsonic acid moieties for surface anchoring to IONPs, along with water soluble PEG blocks to impart colloidal stability in aqueous environments. The resulting polymer‐coated IONPs are evaluated for stability in physiological media and cytocompatibility.
Nhu Thao Huynh, Alexander Rajakanthan, Jurie Tashkandi, Rafia Rafique, Milad Ghorbani, Zihnil A. I. Mazrad, Nicole M. Warne, Kiyonori Suzuki, Karen Alt, Paul Wilson, Kristian Kempe   +10 more
wiley   +1 more source

Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities [PDF]

, 2017
Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new ...
Coluccia, A., Famiglini, V., Hiscott, J., La Regina, G., Lee, J. C., Masci, D., Pelliccia, S., Silvestri, R., Tseng, C. K., Wub, Y. H.   +9 more
core   +1 more source

Spatial Perturbations within an RNA Promoter Specifically Recognized by a Viral RNA-Dependent RNA Polymerase (RdRp) Reveal That RdRp Can Adjust Its Promoter Binding Sites [PDF]

Journal of Virology, 1999
ABSTRACT RNA synthesis during viral replication requires specific recognition of RNA promoters by the viral RNA-dependent RNA polymerase (RdRp). Four nucleotides (−17, −14, −13, and −11) within the brome mosaic virus (BMV) subgenomic core promoter are required for RNA synthesis by the BMV RdRp (R. W. Siegel et al., Proc. Natl. Acad. Sci.
S S, Stawicki, C C, Kao
openaire   +2 more sources