Results 151 to 160 of about 2,150 (202)
Efficient elimination of RNA mycoviruses in aspergillus species using RdRp-inhibitors ribavirin and 2’-C-methylribonucleoside derivatives [PDF]
, 2022 Ayano Ikeda +4 more
openalex +1 more source
Selective Diversity in RNA Viruses: Do They Know How to Evolve? A Hypothesis
BioEssays, Volume 47, Issue 4, April 2025.Among many sophisticated things viruses “learned” during their evolution, could be a simple mechanism for preferential accumulation of genetic variability in regions beneficial for virus survival. Identification of the major players coordinating this selective diversity could find applications in the development of effective prophylactic and ...
Lev G. Nemchinov
wiley +1 more source
Cancer Reports, Volume 8, Issue 4, April 2025.ABSTRACT Background The death rate of hematological malignancies is high, and the death rate of patients with COVID‐19 infection is further increased. Although there have been expert consensus and relevant guidelines to introduce the recommendations of the guidelines for patients with hematological malignancies complicated with COVID‐19 infection ...
Lin Wang +16 more
wiley +1 more source
Papaverine Targets STAT Signaling: A Dual‐Action Therapy Option Against SARS‐CoV‐2
Journal of Medical Virology, Volume 97, Issue 4, April 2025.ABSTRACT Papaverine (PV) has been previously identified as a promising candidate in SARS‐CoV‐2 repurposing screens. In this study, we further investigated both its antiviral and immunomodulatory properties. PV displayed antiviral efficacy against SARS‐CoV‐2 and influenza A viruses H1N1 and H5N1 in single infection as well as in co‐infection.
Philipp Reus +9 more
wiley +1 more source
Novel analogues of a nonnucleoside SARS-CoV-2 RdRp inhibitor as potential antivirotics
Beilstein Journal of Organic ChemistryThe RNA-dependent RNA polymerase (RdRp) represents a prominent target in the discovery and development of new antivirotics against RNA viruses, inhibiting the replication process. One of the most targeted RNA viruses of the last years is, without doubt, SARS-CoV-2, the cause of the recent COVID-19 pandemic.
Luca Julianna Tóth +7 more
openaire +4 more sources