Results 151 to 160 of about 53,016 (292)
Skyrme-force time-dependent Hartree-Fock calculations with axial symmetry [PDF]
, 1981 We discuss axially symmetric time-dependent Hartree-Fock calculations using a finite-range modification of the Skyrme energy functional. The finite-difference forms of the coordinate-space time-dependent Hartree-Fock equations, the method of time ...
Davies, K. T. R., Koonin, S. E.
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PLoS Pathogens, 2016 Flaviviruses comprise major emerging pathogens such as dengue virus (DENV) or Zika virus (ZIKV). The flavivirus RNA genome is replicated by the RNA-dependent-RNA polymerase (RdRp) domain of non-structural protein 5 (NS5).
Siew Pheng Lim +15 more
doaj +1 more source
Computational mechanisms in genetic regulation by RNA
, 2018 The evolution of the genome has led to very sophisticated and complex regulation. Because of the abundance of non-coding RNA (ncRNA) in the cell, different species will promiscuously associate with each other, suggesting collective dynamics similar to ...
Deutsch, J. M.
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SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication. [PDF]
, 2016 Accumulating evidence suggests that viruses hijack cellular proteins to circumvent the host immune system. Ubiquitination and SUMOylation are extensively studied posttranslational modifications (PTMs) that play critical roles in diverse biological ...
Gong, P +9 more
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Scientific Reports, 2018 Human norovirus causes approximately 219,000 deaths annually, yet there are currently no antivirals available. A virtual screening of commercially available drug-like compounds (~300,000) was performed on the suramin and PPNDS binding-sites of the ...
Salvatore Ferla +8 more
doaj +1 more source
BMC Bioinformatics, 2005 Background The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and thus is a validated target for antiviral drugs.
Dutartre Hélène +3 more
doaj +1 more source
The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases [PDF]
, 2015 Thosea asigna virus (TaV), an insect virus belonging to the Permutatetraviridae family, has a positive-sense single-stranded RNA (ssRNA) genome with two overlapping open reading frames, encoding for the replicase and capsid proteins.
Buxaderas, Mònica +3 more
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Heterogeneous catalysis in photo-RDRP : towards green polymer manufacturing
, 2021 The rapid development of reversible deactivation radical polymerization (RDRP) enables the preparation of well-defined polymers with diverse topological architectures and functionalities. In particular, photoinitiated RDRP (photo-RDRP) has gained increasing attention in the past decade due to the use of environmentally friendly and economically benign ...
openaire +2 more sources