Results 11 to 20 of about 5,854,385 (285)

Switching Reactive Oxygen Species into Reactive Nitrogen Species by Photocleaved O2‐Released Nanoplatforms Favors Hypoxic Tumor Repression [PDF]

Advanced Science, 2021
In various reactive oxygen species (ROS)‐based antitumor approaches (e.g., photodynamic therapy), increasing attentions are made to improve ROS level, but the short lifetime that is another decisive hurdle of ROS‐based antitumor outcomes is not even ...
Tao Luo, Duo Wang, Lidong Liu, Yan Zhang, Chuangye Han, Ying Xie, Yan Liu, Jingchen Liang, Guanhua Qiu, Hongxue Li, Danke Su, Junjie Liu, Kun Zhang   +12 more
doaj   +2 more sources

Physiological and pathophysiological role of reactive oxygen species and reactive nitrogen species in the kidney [PDF]

Clinical and Experimental Pharmacology and Physiology, 2018
SummaryEnd‐stage renal disease is a leading cause of morbidity and mortality worldwide. The prevalence of the disease and the number of patients who receive renal replacement therapy are expected to increase in the next decade. Accumulating evidence suggests that chronic hypoxia in the tubulointerstitium represents the final common pathway to end‐stage
Yu Ishimoto, Tetsuhiro Tanaka, Yoko Yoshida, Reiko Inagi   +3 more
openaire   +3 more sources

Demyelination: The Role of Reactive Oxygen and Nitrogen Species [PDF]

Brain Pathology, 1999
This review summarises the role that reactive oxygen and nitrogen species play in demyelination, such as that occurring in the inflammatory demyelinating disorders multiple sclerosis and Guillain‐Barré syndrome. The concentrations of reactive oxygen and nitrogen species (e.g.
Smith, Kenneth J., Kapoor, Raju, Felts, Paul A.   +2 more
openaire   +4 more sources

Modification of DNA structure by reactive nitrogen species as a result of 2-methoxyestradiol–induced neuronal nitric oxide synthase uncoupling in metastatic osteosarcoma cells [PDF]

Redox Biology, 2020
2-methoxyestradiol (2-ME) is a physiological anticancer compound, metabolite of 17β-estradiol. Previously, our group evidenced that from mechanistic point of view one of anticancer mechanisms of action of 2-ME is specific induction and nuclear hijacking ...
Magdalena Gorska-Ponikowska, Agata Ploska, Dagmara Jacewicz, Michal Szkatula, Giampaolo Barone, Giosuè Lo Bosco, Fabrizio Lo Celso, Aleksandra M Dabrowska, Alicja Kuban-Jankowska, Monika Gorzynik-Debicka, Narcyz Knap, Lech Chmurzynski, Lawrence Wawrzyniec Dobrucki, Leszek Kalinowski, Michal Wozniak   +14 more
doaj   +2 more sources

Effects of aluminum on metabolism of reactive oxygen species and reactive nitrogen species in root tips of different Eucalyptus species [PDF]

BMC Plant Biology
On acidified soil, the growth of Eucalyptus is seriously restricted by aluminum (Al) stress. Therefore, breeding Eucalyptus species with excellent Al tolerance, developing the genetic potential of species, and improving tolerance to Al stress are ...
Zilong Ouyang, Bing Liu, Tangkan Li, Tiandao Bai, Weichao Teng   +4 more
doaj   +2 more sources

Reactive nitrogen species in host–bacterial interactions [PDF]

Current Opinion in Immunology, 2019
Reactive nitrogen species play diverse and essential roles in host-pathogen interactions. Here, we review selected recent discoveries regarding nitric oxide (NO) in host defense and the pathogenesis of infection, mechanisms of bacterial NO resistance, production of NO by human macrophages, NO-based antimicrobial therapeutics and NO interactions with ...
Ferric C, Fang, Andrés, Vázquez-Torres
openaire   +4 more sources

Reactive Nitrogen in the Tropical Troposphere [PDF]

, 2013
The aim of this project was to calibrate a thermal-decomposition chemiluminescence (TD-Chem) instrument, capable of measuring the composition of the reactive nitrogen pool at the Cape Verde Atmospheric Observatory (CVAO) in the remote tropical ...
Manning, William D
core   +6 more sources

Evaluation of Inducing Apoptosis as Cell Death Mechanism by Cold Atmospheric Plasma in Cervix Cancer Cell Line (Hela)

مجله دانشکده پزشکی اصفهان, 2020
Background: Cancer is the second leading cause of death in the world and third in Iran. Various methods have been investigated for cancer treatment in which the use of cold atmospheric plasma and plasma-activated medium (PAM) are two new research methods
Tahereh Tayebi, Mahya Aminrayajezeh, Mohammad Reza Khani, Babak Shokri, Hassan Niknejad   +4 more
doaj   +1 more source

DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine. [PDF]

PLoS Pathogens, 2011
Ingested Vibrio cholerae pass through the stomach and colonize the small intestines of its host. Here, we show that V. cholerae requires at least two types of DNA repair systems to efficiently compete for colonization of the infant mouse intestine. These
Bryan W Davies, Ryan W Bogard, Nicole M Dupes, Tyler A I Gerstenfeld, Lyle A Simmons, John J Mekalanos   +5 more
doaj   +1 more source

Reaction Cycles of Halogen Species in the Immune Defense: Implications for Human Health and Diseases and the Pathology and Treatment of COVID-19

Cells, 2020
There is no vaccine or specific antiviral treatment for COVID-19, which is causing a global pandemic. One current focus is drug repurposing research, but those drugs have limited therapeutic efficacies and known adverse effects. The pathology of COVID-19
Qing-Bin Lu
doaj   +1 more source