Results 31 to 40 of about 257,710 (254)

Dysfunctional mitochondrial processes contribute to energy perturbations in the brain and neuropsychiatric symptoms

open access: yesFrontiers in Pharmacology, 2023
Mitochondria are complex endosymbionts that evolved from primordial purple nonsulfur bacteria. The incorporation of bacteria-derived mitochondria facilitates a more efficient and effective production of energy than what could be achieved based on ...
Pascal Büttiker   +7 more
doaj   +1 more source

Reactive Nitrogen Species Reactivities with Nitrones: Theoretical and Experimental Studies [PDF]

open access: yesChemical Research in Toxicology, 2012
Reactive nitrogen species (RNS) such as nitrogen dioxide ((•)NO(2)), peroxynitrite (ONOO(-)), and nitrosoperoxycarbonate (ONOOCO(2)(-)) are among the most damaging species present in biological systems due to their ability to cause modification of key biomolecular systems through oxidation, nitrosylation, and nitration.
Kevin M, Nash   +2 more
openaire   +2 more sources

Bioimaging Probes for Reactive Oxygen Species and Reactive Nitrogen Species

open access: yesJournal of Clinical Biochemistry and Nutrition, 2009
Reactive oxygen species (ROS) play key roles in many pathogenic processes, including carcinogenesis, inflammation, ischemia-reperfusion injury and signal transduction. Also, reactive nitrogen species (RNS) cause various biological events such as neurodegenerative disorders.
openaire   +3 more sources

Antioxidants and skeletal muscle performance: ’Common knowledge’ vs. experimental evidence.

open access: yesFrontiers in Physiology, 2012
Antioxidants are assumed to provide numerous benefits, including better health, a reduced rate of aging, and improved exercise performance. Specifically, antioxidants are commonly ‘prescribed’ by the media, supplement industry, and ‘fitness experts’ for
Andrés eHernández   +2 more
doaj   +1 more source

Photoactivatable nanogenerators of reactive species for cancer therapy

open access: yesBioactive Materials, 2021
In recent years, reactive species-based cancer therapies have attracted tremendous attention due to their simplicity, controllability, and effectiveness.
Xiaohua Zheng, Ph.D.   +5 more
doaj   +1 more source

Oxidative DNA Damage and Repair: Mechanisms, Mutations, and Relation to Diseases

open access: yesAntioxidants, 2023
Oxidative DNA damage (ODD) by reactive oxygen species (ROS) or reactive nitrogen species (RNS) is an inevitable tradeoff for using oxidation processes by living cells as a source of energy [...]
Marina Roginskaya, Yuriy Razskazovskiy
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Evaluation of melatonin levels in saliva in periodontal health and disease: A clinico-biochemical study

open access: yesJournal of International Clinical Dental Research Organization, 2010
Background: Melatonin, a secretory product of the vertebrate pineal gland, activates several elements of the immune system that reduce tissue destruction during the inflammatory response, either directly by scavenging free radical, reactive oxygen ...
Nilkanth Mhaske   +3 more
doaj   +1 more source

Glutathione Participation in the Prevention of Cardiovascular Diseases

open access: yesAntioxidants, 2021
Cardiovascular diseases (CVD) (such as occlusion of the coronary arteries, hypertensive heart diseases and strokes) are diseases that generate thousands of patients with a high mortality rate worldwide.
Deyamira Matuz-Mares   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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