Results 101 to 110 of about 1,596,363 (414)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Reactive Oxygen Species in Metabolic and Inflammatory Signaling.

Circulation Research, 2018
Reactive oxygen species (ROS) are well known for their role in mediating both physiological and pathophysiological signal transduction. Enzymes and subcellular compartments that typically produce ROS are associated with metabolic regulation, and diseases
Steven J Forrester, Daniel S Kikuchi, M. Hernandes, Qian Xu, K. Griendling   +4 more
semanticscholar   +1 more source

Fluorescent Detection of Reactive Oxygen Species in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e Applied to Chronological Lifespan [PDF]

, 2019
During the course of normal aerobic metabolism, cells are exposed to a wide range of reactive oxygen species such as the superoxide anion, hydrogen peroxide, and the hydroxyl radical. These reactive oxygen species (ROS) are highly reactive metabolites of
Bestwick, Megan, Schultz, Kelly
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Immunizing Mice with Influenza Virus-like Particles Expressing the Leishmania amazonensis Promastigote Surface Antigen Alleviates Inflammation in Footpad

Vaccines
Cutaneous leishmaniasis (CL) is a tropical disease endemic in many parts of the world. Characteristic clinical manifestations of CL include the formation of ulcerative skin lesions that can inflict life-long disability if left untreated.
Gi-Deok Eom, Ki Back Chu, Keon-Woong Yoon, Jie Mao, Sung Soo Kim, Fu-Shi Quan   +5 more
doaj   +1 more source

Production and Scavenging of Reactive Oxygen Species in Chloroplasts and Their Functions1

Plant Physiology, 2006
The reaction centers of PSI and PSII in chloroplast thylakoids are the major generation site of reactive oxygen species (ROS). Photoreduction of oxygen to hydrogen peroxide (H2O2) in PSI was discovered over 50 years ago by [Mehler (1951)][1 ...
K. Asada
semanticscholar   +1 more source

High-Sensitivity, High-Resolution Detection of Reactive Oxygen-Species Concentration Using NV Centers [PDF]

arXiv, 2021
Nitrogen-vacancy (NV) color centers in diamond have been demonstrated as useful magnetic sensors, in particular for measuring spin fluctuations, achieving high sensitivity and spatial resolution. These abilities can be used to explore various biological and chemical processes, catalyzed by Reactive Oxygen Species (ROS).
arxiv  

Azurin synthesis from pseudomonas aeruginosa MTCC 2453, properties, induction of reactive oxygen species and p53 stimulated apoptosis in breast carcinoma cells [PDF]

, 2011
Breast cancers are usually treated with surgery and radiation excretes adverse effects. Azurin, a potent anticancer redox protein secreted by Pseudomonas aeruginosa (P.
Mandal, Mahitosh, Mazumadar, Abhijit, Ramachandran, Sankar, Sarkar, Siddik   +3 more
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Respiratory Research
Excessive pulmonary inflammation is the hallmark of respiratory syncytial virus (RSV) infection hindering efficacious RSV vaccine development. Yet, the vast majority of the experimental RSV vaccine studies use laboratory-adapted RSV strains that do not ...
Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan   +7 more
doaj   +1 more source