Results 61 to 70 of about 323,541 (245)

Profiling reading strategies used by Grade 10 English First Additional Language learners in two selected high schools in KwaZulu-Natal

open access: yesLiterator
In order to address learners’ reading difficulties, several researchers recommend the development of their reading profiles. To this end, South Africa is no exception.
Thenjiwe Meyiwa
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Critical thinking strategies in reading [PDF]

open access: yesPorta Linguarum Revista Interuniversitaria de Didáctica de las Lenguas Extranjeras, 2011
The social negotiation maintains that the main roles of the environment are to offer alternative views, to develop knowledge, to seek knowledge that is compatible with students' own construction and understanding of the world. It also enhances critical thinking skills such as studying a subject or problem with open- mindedness, determining the facts of
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Rhetorical Reading for Writing Strategies [PDF]

open access: yesJournal of ELT Research, 2019
This article is based on the plenary talk given at the inaugural UHAMKA International Conference on English Language Teaching (ELT) and Computer Assisted Language Learning (CALL) (UICELL 2018) in Jakarta, Indonesia, 23 November 2018, and focuses on the explanation of reading as a communicative rhetorical act. Outlining the key features of such reading,
openaire   +4 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Investigating Metacognitive Strategies for overcoming Barriers to Reading Comprehension: Insights from a Pakistani Context

open access: yesJournal of Language and Cultural Education, 2018
The main aim of this research was to investigate metacognitive strategies through reading comprehension practice by first year students of engineering departments.
Channa Mansoor Ahmed   +4 more
doaj   +1 more source

READING STRATEGIES IN EFL CLASSROOM: A THEORETICAL REVIEW

open access: yesCendekia: Jurnal Pendidikan dan Pembelajaran, 2014
Teaching reading has been long discussed in the context of English teaching curriculum in Indonesia.  The ground of English curriculum (e.g. 1984, 1994, 2004 English curriculum) lays reading as the main model of teaching English in the secondary school ...
Teguh Budiharso
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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