Results 81 to 90 of about 637,318 (299)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Primers used for real-time RT-PCR.

open access: yes, 2019
Primers used for real-time RT-PCR.
Taku Kitanaka (3350276)   +7 more
core   +2 more sources

Oligonucleotides designed for real time RT-PCR.

open access: yes, 2013
Oligonucleotides designed for real time RT-PCR.
Pedro Pousão-Ferreira (328950)   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Oligonucleotides used for real-time RT-PCR.

open access: yes, 2016
Oligonucleotides used for real-time RT-PCR.
Thomas W. Göbel (391045)   +4 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Quantification of bovine cytokine gene expression using real-time RT-PCR methodology

open access: yesGenetics and Molecular Biology, 2007
T cells produce cytokines that affect host response to infection. This paper reports real-time RT-PCR conditions and validation steps for accurate quantification of Bos indicus cytokines, interleukin (IL)-2, IL-4, IL-8, IL12p-35, IL-13, tumoral necrosis ...
Lilian Giotto Zaros   +3 more
doaj   +1 more source

Primers used for real-time RT-PCR

open access: yes, 2016
Primers used for real-time RT ...
Kohta Ohnishi (387891)   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Primers for quantitative real-time RT-PCR.

open access: yes, 2015
Primers for quantitative real-time RT-PCR.
Lucia Mazzolai (278098)   +4 more
core   +1 more source

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