Results 211 to 220 of about 3,983 (230)

Rebaudioside A: Two-generation reproductive toxicity study in rats

Food and Chemical Toxicology, 2008
Rebaudioside A was administered via the diet to male and female Han Wistar rats at 0, 7500, 12,500, and 25,000ppm for two generations. Rebaudioside A treatment was not associated with any signs of clinical toxicity or adverse effects on body weight, body weight gain, or food consumption.
Leslie L, Curry, Ashley, Roberts, Nigel, Brown   +2 more
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Rebaudioside, a novel agent of glycoside clathration of pharmacons

Doklady Biological Sciences, 2009
205 Glycyrrhizinic acid and stevioside, glycosides of higher terpenoids, are capable of in vivo formation of clathrates with pharmacons with various types of activity. This property of glycosides allows the effective dose to be substantially decreased (by a factor of 10– 100), with the basic activity being preserved and novel pharmacological effects ...
T G, Tolstikova, A O, Bryzgalov, M V, Khvostov, G A, Tolstikov   +3 more
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Combined enzymatic modification of stevioside and rebaudioside A

Applied Biochemistry and Microbiology, 2006
Cyclodextrin glucanotransferases (CGTases, EC 2.4.1.19) produced by mesophilic, thermophilic, alkaliphilic, and halophilic bacilli were used for transglycosylating stevioside and rebaudiosides A with the use of starch as a donor. CGTases produced by B. stearothermophilus B-5076 B. macerans BIO-4m were the most effective biocatalysts. This method can be
V. T. Kochikyan, A. A. Markosyan, L. A. Abelyan, A. M. Balayan, V. A. Abelyan   +4 more
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RQ3, A Natural Rebaudioside D Isomer, Was Obtained from Glucosylation of Rebaudioside A Catalyzed by the CGTase Toruzyme 3.0 L

Journal of Agricultural and Food Chemistry, 2019
In this study, a monoglucosyl rebaudioside A product was isolated from the mixture of glucosylated rebaudioside A obtained from the most reported and industrial used cyclodextrin glycosyl transferase, Toruzyme 3.0 L (CGTase, Toruzyme 3.0 L). The molecular structure of the monoglucosyl rebaudioside A was characterized using LC-MS/MS and methylation ...
Qingbin Guo, Tongtong Zhang, Nifei Wang, Yongmei Xia, Zhuoyu Zhou, Jian-rong Wang, Xuefeng Mei   +6 more
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The non-cytotoxicity characterization of rebaudioside A as a food additive

Food and Chemical Toxicology, 2014
To evaluate the cytotoxicity of high-purity rebaudioside A (reb A, 99.16%) as a food ingredient, a combination of several methods, including tetrazolium-based colorimetric assay (MTT), lactate dehydrogenase assay (LDH), enzyme-linked immunosorbent assay (ELISA), real-time PCR (qPCR), high-performance liquid chromatography (HPLC), and two-dimensional ...
Xiaoli, Wu, Baogui, Wang, Tingtao, Chen, Min, Gan, Xingxing, Chen, Fei, Chen, Hua, Wei, Feng, Xu   +7 more
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Total Synthesis and Structural Revision of Rebaudioside S, a Steviol Glycoside

The Journal of Organic Chemistry, 2020
The total synthesis of rebaudioside S, a minor steviol glycoside from the leaves of Stevia rebaudiana, was investigated via a modular strategy, culminating not only in the first and highly efficient synthesis of Reb-S and analogues thereof but also in the revision of the originally proposed structure. The modular strategy dictated the application of C2-
Guo-En Wen, Hui Liu, Qi-Shuang Yin, Jin-Xi Liao, Yuan-Hong Tu, Qing-Ju Zhang, Jian-Song Sun   +6 more
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Heterologous expression of EUGT11 from Oryza sativa in Pichia pastoris for highly efficient one-pot production of rebaudioside D from rebaudioside A

International Journal of Biological Macromolecules, 2020
Rebaudioside D is a promising sweetener due to its zero calorie and high sweetness. Here, a transglucosylase gene eugt11 from Oryza sativa was for the first time expressed in Pichia pastoris, and transformant XE-3 showed the highest expression levels in pH 5.5 BMMY media containing 0.75% methanol.
Zhenyang, Wang, Jiefang, Hong, Siyuan, Ma, Tong, Huang, Yuanyuan, Ma, Wei, Liu, Wenbin, Liu, Zhiming, Liu, Hao, Song   +8 more
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Enzymatic Synthesis of Glucosyl Rebaudioside A and its Characterization as a Sweetener

Journal of Food Science, 2019
Abstract Rebaudioside A was modified via glucosylation by recombinant dextransucrase of Leuconostoc lactis EG001 in Escherichia coli BL21 (DE3), forming single O
So-Hyeon, Lee, Jin-A, Ko, Hae-Soo, Kim, Min-Ho, Jo, Joong-Su, Kim, Doman, Kim, Jeong-Yong, Cho, Young-Jung, Wee, Young-Min, Kim   +8 more
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Convergent synthesis of steviol glycosides rebaudioside a and M

Carbohydrate Research
Steviol glycosides, a natural health-focused sweetener, is receiving increasing attention. Herein, an efficient and concise approach for the convergent synthesis of Rebaudioside A and M has been devised. This method features a AuCl3-tBuCN cooperative catalysis to achieve highly 1, 2-trans stereoselective glycosidation of a C2-branched trisaccharide ...
Yuanyuan Li, Haoru Zhuang, Xuerui Tao, Yingguo Liu, Tianlu Li, Peng Peng   +5 more
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Konsumentenakzeptanz von ausgewählten Erfrischungsgetränten mit Rebaudiosid A-

2011
Since the consumption of sugar-containing soft drinks is considered as a possible cause of obesity and diabetes, health-conscious consumers are resorting increasingly to low-calorie products, in which the sugar is replaced by artificial sweeteners. Rebaudioside A (RA), the main component of the plant Stevia rebaudiana, is a non-caloric sweetener of ...
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