Results 51 to 60 of about 119,693 (290)

Altered expression of adenosine A1 receptor in the paraventricular thalamus and its role in the regulation of sleep

open access: yes陆军军医大学学报
Objective‍ ‍To explore the expression profile of adenosine A1 receptor in the paraventricular thalamic nucleus (PVT) in wakefulness/sleep state and its role in regulating sleep.
ZHU Yifeng, WANG Na, HU Junya
doaj   +1 more source

The role of cGMP on adenosine A1 receptor-mediated inhibition of synaptic transmission at the hippocampus

open access: yesFrontiers in Pharmacology, 2016
Both adenosine A1 receptor and cGMP inhibit synaptic transmission at the hippocampus and recently it was found that A1 receptor increased cGMP levels in hippocampus, but the role of cGMP on A1 receptor-mediated inhibition of synaptic transmission remains
Isa ePinto   +5 more
doaj   +1 more source

Adenosinergic regulation of binge-like ethanol drinking and associated locomotor effects in male C57BL/6J mice [PDF]

open access: yes, 2015
We recently observed that the addition of caffeine (a nonselective adenosine receptor antagonist) to a 20% ethanol solution significantly altered the intoxication profile of male C57BL/6J (B6) mice induced by voluntary binge-like consumption in the ...
Boehm II, Stephen L., Fritz, Brandon M.
core   +1 more source

A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain

open access: yesNeuroImage, 2023
The EEG alpha rhythm (∼ 8–13 Hz) is one of the most salient human brain activity rhythms, modulated by the level of attention and vigilance and related to cerebral energy metabolism.
Naemi L. Tichelman   +12 more
doaj  

Electroacupuncture-induced neuroprotection against focal cerebral ischemia in the rat is mediated by adenosine A1 receptors

open access: yesNeural Regeneration Research, 2017
The activation of adenosine A1 receptors is important for protecting against ischemic brain injury and pretreatment with electroacupuncture has been shown to mitigate ischemic brain insult.
Qin-xue Dai   +7 more
doaj   +1 more source

Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slices [PDF]

open access: yes, 2003
Electrophysiological recordings were used to investigate the effects of ATP analogues on [theta]-burst-induced long-term potentiation (LTP) in rat hippocampal slices.
Almeida, T.   +4 more
core   +1 more source

Adenosine A1 receptor antagonist improves intradialytic hypotension [PDF]

open access: yesKidney International, 2006
Intradialytic hypotension is a most frequent complication of hemodialysis and may contribute to cardiovascular events and high mortality. There is a hypothesis that an increase in adenosine generation during hemodialysis may cause vasodilation and a decrease in cardiac output, which results in systemic hypotension.
Masatsugu Hori   +6 more
openaire   +3 more sources

Evidence for the presence of A1 adenosine receptors in the aorta of spontaneously hypertensive rats [PDF]

open access: yes, 2001
1 Isolated aortic rings (endothelium-intact and -denuded) from spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats were used in this study to examine the vasoactive e ects of various adenosine analogues.
AUCH-SCHWELK   +32 more
core   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Adenosine A1 Receptor Agonist 2-chloro-N6-cyclopentyladenosine and Hippocampal Excitability During Brain Development in Rats

open access: yesFrontiers in Pharmacology, 2019
Objective: The adenosinergic system may influence excitability in the brain. Endogenous and exogenous adenosine has anticonvulsant activity presumably by activating A1 receptors.
Petr Fabera   +11 more
doaj   +1 more source

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