Results 221 to 230 of about 271,431 (312)

Angiotensin-(1–1) Suppresses Hepatocellular Carcinoma Growth and Angiogenesis via Complex Interactions of Angiotensin II Type 1 Receptor, Angiotensin II Type 2 Receptor and Mas Receptor

Molecular Medicine, 2015
Yanping Liu, Bin Li, Ximing Wang, Guishuang Li, Rui Shang, Jianmin Yang, Jiali Wang, Meng Zhang, Yuguo Chen, Yun Zhang, Cheng Zhang, Panpan Hao   +11 more
openaire   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Zilebesiran: an RNA interference agent-its need and potential to transform hypertension treatment. [PDF]

Egypt Heart J
Verma S, Pradhan A, Thandi P.
europepmc   +1 more source

Type-1 Angiotensin II Receptor-Associated Protein [PDF]

, 2020
openaire   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Current Management of Resistant Hypertension in Patients with Intracerebral Hemorrhage. [PDF]

Int J Mol Sci
Nguyen M, Oh S, King M, Yu W, Ramadan AR.   +4 more
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Endocrinological aspects of sarcopenic obesity. [PDF]

Ann Med
Minnetti M, Poggiogalle E, Frigerio F, Piciocchi C, Pierantozzi G, Di Vincenzo O, Pinto A, Gianfrilli D, Isidori AM, Migliaccio S, Donini LM.   +10 more
europepmc   +1 more source

Association between serum bicarbonate and low mid‐upper arm circumference in patients with non‐dialysis‐dependent chronic kidney disease: A cross‐sectional study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, Wataru Akita, Akihito Ohta, Shinichi Uchida, Soichiro Iimori   +13 more
wiley   +1 more source

Therapeutic Advances in Diabetic Kidney Disease: 30 Years of Evidence and the Rise of the "Fantastic Four" in Nephrology.

Cardiorenal Med
Husain-Syed F, Yuecel G, Daschner C, Jochims J, Yazdani B.   +4 more
europepmc   +1 more source