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[Angiotensin II type 1 and type 2 receptor].
Nihon rinsho. Japanese journal of clinical medicine, 2009The octapeptide angiotensin II (AngII) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and contributes to the progression of cardiovascular remodeling. AngII activates AngII type 1 (AT1) receptor and type 2 (AT2) receptor, both of which belong to the seven-transmembrane, G protein-coupled receptor family.
Hiroshi, Akazawa, Issei, Komuro
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Endocytosis and signaling of angiotensin II type 1 receptor
2023A vasoactive octapeptide angiotensin II (Ang II) hormone is the key regulator of the renin-angiotensin system (RAS). It binds with the two different plasma membrane receptors like angiotensin II type 1 (AT1) and type 2 (AT2) and consequence various biological responses occur. Further, AT1 has two subtypes such as AT1A and AT1B.
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The Angiotensin II Type 1 Receptor Antagonists
Archives of Internal Medicine, 1995The angiotensin II (AII) type 1 receptor antagonists represent a new pharmacologic class of drugs that are specifically designed to displace All from its type 1 receptor subtype. These drugs antagonize AII-induced biologic actions, including smooth-muscle contraction, sympathetic pressor mechanisms, and aldosterone release.
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Angiotensin II type 1 receptor antagonists
Biochemical Pharmacology, 2000Patrick M.L Vanderheyden +2 more
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Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
Nature Reviews Drug Discovery, 2023P V Kolkhir +2 more
exaly
Type VII secretion systems: structure, functions and transport models
Nature Reviews Microbiology, 2021Angel Rivera-Calzada +2 more
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Targeting inflammation in the treatment of type 2 diabetes: time to start
Nature Reviews Drug Discovery, 2014Marc Y Donath
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