Results 21 to 30 of about 181,641 (286)

Beneficial Effect of Mas Receptor Deficiency on Vascular Cognitive Impairment in the Presence of Angiotensin II Type 2 Receptor

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThe classical renin‐angiotensin system is known as the angiotensin (Ang)‐converting enzyme/Ang II/Ang type 1 receptor axis, which induces various organ damage including cognitive decline.
Akinori Higaki, Masaki Mogi, Jun Iwanami, Li‐Juan Min, Hui‐Yu Bai, Bao‐Shuai Shan, Masayoshi Kukida, Toshifumi Yamauchi, Kana Tsukuda, Harumi Kan‐no, Shuntaro Ikeda, Jitsuo Higaki, Masatsugu Horiuchi   +12 more
doaj   +1 more source

Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?

Frontiers in Pharmacology, 2020
G-protein–coupled receptors (GPCRs) are targets for around one third of currently approved and clinical prescribed drugs and represent the largest and most structurally diverse family of transmembrane signaling proteins, with almost 1000 members ...
Natalia L. Rukavina Mikusic, Mauro G. Silva, Angélica M. Pineda, Mariela M. Gironacci   +3 more
doaj   +1 more source

Angiotensin II modulates THP-1-like macrophage phenotype and inflammatory signatures via angiotensin II type 1 receptor

Frontiers in Cardiovascular Medicine, 2023
Angiotensin II (Ang II) is a major component of the renin–angiotensin or renin–angiotensin–aldosterone system, which is the main element found to be involved in cardiopathology.
Tlili Barhoumi, Fatmah A. Mansour, Maroua Jalouli, Hassan S. Alamri, Rizwan Ali, Abdel Halim Harrath, Maha Aljumaa, Mohamed Boudjelal   +7 more
doaj   +1 more source

Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]

, 2005
Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
core   +1 more source

Angiotensin Type 1 Receptor Blockers in Heart Failure

Current Drug Targets, 2020
Homeostasis in the cardiovascular system is maintained by physiological functions of the Renin Angiotensin Aldosterone System (RAAS). In pathophysiological conditions, over activation of RAAS leads to an increase in the concentration of Angiotensin II (AngII) and over activation of Angiotensin Type 1 Receptor (AT1R), resulting in vasoconstriction ...
Khuraijam Dhanachandra, Singh, Sadashiva S, Karnik   +1 more
openaire   +3 more sources

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice [PDF]

, 2003
Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension.
Kenyon, C J, Joel K. Elmquist, Elmquist, Joel K., Flier, Jeffrey S., Jonathan R. Seckl, Yamamoto, H, Yamamoto, Hiroshi, Mullins, J J, John J. Mullins, Shinyama, H, Shinyama, Hiroshi, Masuzaki, H, Nicholas M. Morton, Janice M. Paterson, Paterson, Janice M., Sharp, M G F, Jeffrey S. Flier, Seckl, J R, Sharp, Matthew G. F., Masuzaki, Hiroaki, Paterson, J M, Matthew G.F. Sharp, Seckl, Jonathan R., Hiroshi Yamamoto, Morton, Nicholas M., Stewart Fleming, Elmquist, J K, Morton, N M, Hiroaki Masuzaki, Flier, J S, Mullins, John J., Fleming, S, Hiroshi Shinyama, Fleming, Stewart, Kenyon, Christopher J., Christopher J. Kenyon   +35 more
core   +1 more source

Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes [PDF]

, 2008
<b>Background:</b> Adiponectin is secreted by adipose tissue and may play a role in cardiovascular disease. We examined adiponectin levels in patients with type 2 diabetes who participated in the Telmisartan vs.
Fauvel, J.P., Raff, U., R. E. Schmieder, C. Delles, Ruilope, L.M., Mimran, A., J. P. Fauvel, Delles, C., U. Raff, A. Mimran, Schmieder, R.E., L. M. Ruilope   +11 more
core   +1 more source

Type 1 angiotensin II receptors in human endometrium [PDF]

Molecular Human Reproduction, 1996
From evidence based on the use of specific receptor subtype antagonists, it has generally been assumed that human uterine tissue contains only type 2 (AT2) angiotensin II (AII) receptor subtype. Using a monoclonal antibody, 6313/G2, directed against a specific sequence in the extracellular domain of the type 1 AII receptor (AT1), in immunocytochemical ...
E, Saridogan, O, Djahanbakhch, J R, Puddefoot, C, Demetroulis, R, Dawda, A J, Hall, G P, Vinson   +6 more
openaire   +2 more sources

Angiotensin Receptor Blocker (ARB): Is it Effective to Prevent Cerebral Malaria? [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Cerebral malaria is a severe complication of plasmodium falciparum infection with 15-25% mortality rates. Sequestration of infected red blood cells disrupts the blood brain barried leading to irreversible brain damage, impacting quality of life.
I Gusti Ayu Hiranandini Prawista, Davin Beta Tadeo, I Gusti Ngurah Ariestha Satya Diksha, Darren Junior, Richard Christian Suteja, Cokorda Agung Wahyu Purnamasidhi, Saktivi Harkitasari   +6 more
doaj   +1 more source

Differential Regulation of Intracisternally Injected Angiotensin II-Induced Mechanical Allodynia and Thermal Hyperalgesia in Rats

Biomedicines, 2023
The present study examined the underlying mechanisms of mechanical allodynia and thermal hyperalgesia induced by the intracisternal injection of angiotensin (Ang) II.
Ki-Don Park, Jo-Young Son, Hak-Kyun Kim, Yu-Mi Kim, Jin-Sook Ju, Min-Jeong Jo, Min-Kyoung Park, Min-Kyung Lee, Dong-Kuk Ahn   +8 more
doaj   +1 more source