Results 201 to 210 of about 270,851 (310)

The Apelinergic System in Kidney Disease: Novel Perspectives. [PDF]

Int J Mol Sci
Saladich-Cavallé S, Núñez-Delgado S, Huo L, Pons-Pellicer F, Martínez-Díaz I, Jacobs-Cachá C, Bermejo S, Vilardell-Vilà J, Soler MJ.   +8 more
europepmc   +1 more source

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake, Yoshitsugu Chigusa, Haruta Mogami, Satoshi Morita, Masaki Mandai   +4 more
wiley   +1 more source

Extent and predictors of guideline-directed medical therapy optimization during cardiac rehabilitation in patients with heart failure. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Nicolas C, Girerd N, Duarte K, Huttin O, Djaballah K, Felloni J, Baudry G, Monzo L.   +7 more
europepmc   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Direct Renin Inhibition With Aliskiren Compared to Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Hypertension: A Systematic Review. [PDF]

Cureus
Gapizov A, Mohammad A, Singla S, Singla B, Kumawat S, Ajay, Ali Z.   +6 more
europepmc   +1 more source

Nephrological perspectives on the underutilization of SGLT2is in heart failure and chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı, Ömer Faruk Akçay, Emre Yaşar, Ülver Derici, Galip Güz   +4 more
wiley   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

iMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang, Xiangqiu Chen, Tao Wu, Xichun Zheng, Shaohua Zeng, Qingchun Zhou, Wen Ma, Hao Lin, Donglin Sun   +8 more
wiley   +1 more source

Sacubitril/valsartan as add-on to standard therapy in patients with heart failure: A randomized controlled trial. [PDF]

World J Exp Med
Dhawan R, Mittal R, Kumar A, Laller KS, Gill PS, Rag A, Mittal N.   +6 more
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

RAAS antagonists dampen the SARS-CoV-2 infection in ex-vivo cultured human precision-cut lung slices. [PDF]

Respir Res
Mahavadi P, Korfei M, Müller-Ruttloff C, Ruppert C, Krauss E, Dorfmüller P, Gattenloehner S, Dimmeler S, El Agha E, Bellusci S, Herold S, Witte B, Ziebuhr J, Guenther A.   +13 more
europepmc   +1 more source