Results 31 to 40 of about 21,687 (230)

Escape steering by cholecystokinin peptidergic signaling

Cell Reports, 2022
Summary: Escape is an evolutionarily conserved and essential avoidance response. Considered to be innate, most studies on escape responses focused on hard-wired circuits.
Lili Chen, Yuting Liu, Pan Su, Wesley Hung, Haiwen Li, Ya Wang, Zhongpu Yue, Ming-Hai Ge, Zheng-Xing Wu, Yan Zhang, Peng Fei, Li-Ming Chen, Louis Tao, Heng Mao, Mei Zhen, Shangbang Gao   +15 more
doaj   +1 more source

Dietary squid paste supplementation promotes feed intake via brain-gut dynamic response in Chinese soft-shelled turtle Pelodiscus sinensis [PDF]

PeerJ, 2020
Background As the primary source of protein for aquaculture, fishmeal has reached the extremity of sustainable development, our previous studies have proven that rice protein concentrate and squid paste are outstanding protein source and stimulant for ...
Cunxin Sun, Yu Qian, Wenbin Liu, Weina Xu, Kaizhou Wang, Bo Liu   +5 more
doaj   +2 more sources

Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion [PDF]

, 2010
Context: Glucagon-like peptide-1 (GLP-1) is produced by specialized cells in the gut and secreted in response to carbohydrates and lipids. The mechanisms regulating fat-stimulated GLP-1 release have, however, not been clarified in detail.
Schirra, Joerg, D'Amato, Massimo, Göke, Burkhard, Drewe, Juergen, Beglinger, Svetlana, Beglinger, Christoph   +5 more
core   +1 more source

Effects of galantamine on social interaction impairments in cholecystokinin receptor-2 overexpression mice

Journal of Pharmacological Sciences, 2022
We examined whether galantamine (GAL), a cholinesterase inhibitor and allosteric potentiating ligand for α7 nicotinic acetylcholine receptor (nAChR), had an impact on emotional abnormalities in forebrain-specific cholecystokinin receptor-2 overexpressed ...
Shota Tanase, Takayoshi Mamiya, Shogo Nagata, Yusuke Ikawa, Ya-Ping Tang, Masayuki Hiramatsu, Toshitaka Nabeshima   +6 more
doaj   +1 more source

Cholecystokinin 1 Receptor – A Unique G Protein-Coupled Receptor Activated by Singlet Oxygen (GPCR-ABSO)

Frontiers in Physiology, 2018
Plasma membrane-delimited generation of singlet oxygen by photodynamic action with photosensitizer sulfonated aluminum phthalocyanine (SALPC) activates cholecystokinin 1 receptor (CCK1R) in pancreatic acini.
Hong Ning Jiang, Yuan Li, Wen Yi Jiang, Zong Jie Cui   +3 more
doaj   +1 more source

Cionin, a vertebrate cholecystokinin/gastrin homolog, induces ovulation in the ascidian Ciona intestinalis type A

Scientific Reports, 2021
Cionin is a homolog of vertebrate cholecystokinin/gastrin that has been identified in the ascidian Ciona intestinalis type A. The phylogenetic position of ascidians as the closest living relatives of vertebrates suggests that cionin can provide clues to ...
Tomohiro Osugi, Natsuko Miyasaka, Akira Shiraishi, Shin Matsubara, Honoo Satake   +4 more
doaj   +1 more source

Preclinical evaluation of radiolabeled DOTA-derivatized cyclic minigastrin analogs for targeting cholecystokinin receptor expressing malignancies. [PDF]

, 2011
Item does not contain fulltextPURPOSE: Targeting of cholecystokinin receptor expressing malignancies such as medullary thyroid carcinoma is currently limited by low in vivo stability of radioligands.
Jean-Claude Reubi, von Guggenberg, Elisabeth, Decristoforo, C., Elisabeth von Guggenberg, Rangger, C., Clemens Decristoforo, Sosabowski, J., Guggenberg, E. von, Laverman, P., Decristoforo, Clemens, Christine Rangger, Reubi, Jean-Claude, Irene Johanna Virgolini, Reubi, J.C., Peter Laverman, Laverman, Peter, Rangger, Christine, Sosabowski, Jane, Virgolini, I.J., Virgolini, Irene Johanna, Jane Sosabowski   +20 more
core   +1 more source

Heterogeneity of cholecystokinin receptors in pancreas

Biochemical and Biophysical Research Communications, 1987
Specific labeling of a major Mr 85-95 K protein was obtained using the SH, NH2 heterobifunctional cross-linker m-maleimidobenzoyl N-hydroxysuccinimide ester (MBS) to affinity label cholecystokinin (CCK) receptors on rat pancreatic plasma membranes, pancreatic acinar cells and acinar cell tumor membranes with 125I-CCK-33.
L D, Madison, J D, Jamieson, S A, Rosenzweig   +2 more
openaire   +2 more sources

Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target

Molecular Pain, 2016
Burn injury is a cause of significant mortality and morbidity worldwide and is frequently associated with severe and long-lasting pain that remains difficult to manage throughout recovery.
Kathleen Yin BPharm, Jennifer R Deuis PhD, Richard J Lewis PhD, Irina Vetter PhD   +3 more
doaj   +1 more source

Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol

Journal of Lipid Research, 2012
Recent studies indicate that membrane cholesterol can associate with G protein-coupled receptors (GPCRs) and affect their function. Previously, we reported that manipulation of membrane cholesterol affects ligand binding and signal transduction of the ...
Ross M. Potter, Kaleeckal G. Harikumar, S.Vincent Wu, Laurence J. Miller   +3 more
doaj   +1 more source