Results 41 to 50 of about 6,575 (222)

Distribution and colocalization of melatonin 1a-receptor and NADPH-d in the trigeminal system of rat [PDF]

PeerJ, 2019
Melatonin and nitric oxide (NO) are involved in orofacial signal processing in the trigeminal sensory system. The aim of the present study was to examine the distribution of melatonin 1a-receptor (MT1) and its colocalization with nicotinamide adenine ...
Yifan He, Wenguo Fan, Yue Xu, Yong liang Liu, Hongwen He, Fang Huang   +5 more
doaj   +2 more sources

Comparison of melatonin with growth factors in promoting precursor cells proliferation in adult mouse subventricular zone [PDF]

, 2016
Melatonin, secreted mainly by the pineal gland, plays roles in various physiological functions including protecting cell death. We showed in previous study that the proliferation and differentiation of precursor cells from the adult mouse subventricular ...
Ekthuwapranee, Kasima, Govitrapong, Piyarat, Sotthibundhu, Areechun   +2 more
core   +1 more source

Melatonin Receptors: A Key Mediator in Animal Reproduction

Veterinary Sciences, 2022
Melatonin, a hormone produced by the mammalian pineal gland, influences various physiological activities, many of which are related to animal reproduction, including neuroendocrine function, rhythm regulation, seasonal behavior, gonadogenesis, gamete ...
Yuan Gao, Shuqin Zhao, Yong Zhang, Quanwei Zhang   +3 more
doaj   +1 more source

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing, Ando, Andrew S. I. Loudon, Ashburner, Bae, Barrett, Bartness, Bechtold, Benoit Malpaux, Bockers, Bockers, Bockmann, Brahimi-Horn, Camon, Carr, Chemineau, Chen, Curlewis, Daphne Mouzaki, Dardente, Dave W. Burt, David Waddington, Draghici, Dupre, Fukuhara, Gerald A. Lincoln, Ghorbel, Graham, Grossmann, Hanon, Hazlerigg, Hazlerigg, Hazlerigg, Hogenesch, Hu, Hu, Johnston, Johnston, Johnston, Julian R. E. Davis, Kel, Kijas, Klosen, Ko, Lamolet, Lee, Lincoln, Lincoln, Lincoln, Lincoln, Malpaux, Merks, Messager, Michan, Morgan, Morgan, Mutoh, Nakao, Naya, Naya, Nilaweera, Oki, Poulin, Reick, Revollo, Richard Talbot, Roepke, Rutter, Samal, Sandrine M. Dupré, Schroeder, Segawa, Stehle, Stirland, Storey, Su, Tobler, Tournier, Wagner, Westfall, Williams, Wittkowski, Yang, Yokoyama   +83 more
core   +2 more sources

Mitochondria-targeted melatonin photorelease supports the presence of melatonin MT1 receptors in mitochondria inhibiting respiration

Cell Chemical Biology, 2023
The presence of signaling-competent G protein-coupled receptors in intracellular compartments is increasingly recognized. Recently, the presence of Gi/o protein-coupled melatonin MT1 receptors in mitochondria has been revealed, in addition to the plasma membrane.
Somalo-Barranco, Gloria, Pagano Zottola, Antonio, Abdulrahman, Abdulrasheed, El Zein, Rami, Cannich, Astrid, Muñoz, Lourdes, Serra, Carme, Oishi, Atsuro, Marsicano, Giovanni, Masri, Bernard, Bellocchio, Luigi, Llebaria, Amadeu, Jockers, Ralf   +12 more
openaire   +3 more sources

Regulation of pituitary MT1 melatonin receptor expression by gonadotrophin-releasing hormone (GnRH) and early growth response factor-1 (Egr-1): in vivo and in vitro studies. [PDF]

PLoS ONE, 2014
Melatonin receptor expression exhibits profound developmental changes through poorly understood mechanisms. In mammals, a current model suggests that pubertal reactivation of gonadotrophin-releasing hormone (GnRH) secretion down-regulates MT1 melatonin ...
Sung-Eun Bae, Ian K Wright, Cathy Wyse, Nathalie Samson-Desvignes, Pascale Le Blanc, Serge Laroche, David G Hazlerigg, Jonathan D Johnston   +7 more
doaj   +1 more source

From implantation to birth: insight into molecular melatonin functions [PDF]

, 2018
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland, acting as a neuroendocrine transducer of photoperiodic information during the night.
Carlomagno, Gianfranco, Minini, Mirko, Tilotta, Marco, Unfer, Vittorio   +3 more
core   +1 more source

Rhythmic Expression of Functional MT1 Melatonin Receptors in the Rat Adrenal Gland [PDF]

Endocrinology, 2007
We previously demonstrated that melatonin is involved in the regulation of adrenal glucocorticoid production in diurnal primates through activation of MT1 membrane-bound melatonin receptors. However, whether melatonin has a similar role in nocturnal rodents remains unclear.
Richter, Hans G., Torres Farfán, Claudia, García Sesnich, Jocelyn, Abarzúa Catalán, Lorena, Henríquez Luna, Mauricio, Alvarez Felmer, Mauro, Gaete, Fernando, Rehren, Germán E., Serón Ferré, María   +8 more
openaire   +4 more sources

Melatonin regulates rabbit sperm motility and kinematics via the MT1/PKC signaling pathway [PDF]

Animal Bioscience
Objective Melatonin, a highly conserved molecule, plays an essential role in various physiological functions. Research suggests that incorporating melatonin into semen extender enhances livestock sperm viability.
Chongchong Wang, Yanyan Zhang, Shiwen He, Biao Jiang, Jinglei Huang, Hui Peng   +5 more
doaj   +1 more source

Melatonin signaling in mouse cerebellar granule cells with variable native MT1 and MT2 melatonin receptors [PDF]

Brain Research, 2008
Although G protein-coupled MT1 and MT2 melatonin receptors are expressed in neurons of the mammalian brain including in humans, relatively little is known about the influence of native MT1 and MT2 melatonin receptors on neuronal melatonin signaling. Whereas human cerebellar granule cells (CGC) express only MT1 receptors, mouse CGC express both MT1 and ...
IMBESI, MARTA, UZ T, DZITOYEVA S, GIUSTI, PIETRO, MANEV H.   +4 more
openaire   +2 more sources