A szezonális depresszió etiopatologiája és terápiás lehetóségei [PDF]
To understand the etiology of seasonal affective disorder (SAD) heterogeneous biological, psychological and environmental mechanisms needs to be considered.
Bagdy, György +3 more
core
Structure-function study of ubiquitin c-terminal hydrolase L1 (UCH-L1) by NMR spectroscopy - insights into UCH-L1 mutation's association with the risk of Parkinson's disease [PDF]
Poster Presentation: P72Protein ubiquitination and deubiquitination, play important roles in many aspects of cellular mechanisms. Its defective regulation results in diseases that range from developmental abnormalities to neurodegenerative diseases and ...
Hu, HY, Sze, KH, Tse, HS
core
Neuropathic pain: targeting the melatonin MT2 receptor
Neuropathic pain affects a large proportion of the population and reduces a person’s ability to perform optimally. In South Africa, there are a host of factors that hinder the correct diagnosis and treatment of neuropathic pain. Patients suffering from neuropathic pain are treated suboptimally with NSAIDS and opioids as first-line therapy.
N. Smith, H. Ismail, N. Schellack
openaire +2 more sources
Integrating classical and quantum mechanics in melatonin receptors for structure-guided drug design
Although melatonin receptor agonists are acknowledged for their therapeutic potential for managing sleep problems, the structural optimization of these compounds is made challenging by variations in crystallographic data.
Gabriela de Lima Menezes +9 more
doaj +1 more source
Objective: To analyze the impact of using music therapy to improve the sleep quality and mental health of nurses who suffer from circadian rhythm sleep disorders.
Xuan Wang +3 more
doaj +1 more source
Regulatory role of proheparanase with peri-synaptic heparan sulfate proteoglycan and AMPA-type glutamate receptor in synaptic plasticity [PDF]
Poster Presentation: P59AMPA-type glutamate receptors (AMPAR) govern excitatory synaptic transmission. Perineuronal heparan sulfates (HS) have been implicated in controlling the open-state of AMPAR.
Cham, WC +4 more
core
Sex-Dependent Effects of Rivastigmine on Melatonin Receptors in Middle-Aged Rats. [PDF]
Ünal NA +4 more
europepmc +1 more source
Melatonin Suppresses NLRP3 Inflammasome Activation via SIRT1-Mediated ETS1 Deacetylation to Attenuate LPS-Induced Pyroptosis in Alveolar Epithelial Cells. [PDF]
He F +7 more
europepmc +1 more source

