Results 91 to 100 of about 13,945 (210)

Acetylcholine-induced inhibition of presynaptic calcium signals and transmitter release in the frog neuromuscular junction

Frontiers in Physiology, 2016
Acetylcholine (ACh), released from axonal terminals of motor neurones in neuromuscular junctions regulates the efficacy of neurotransmission through activation of presynaptic nicotinic and muscarinic autoreceptors.
Eduard Khaziev, Eduard Khaziev, Eduard Khaziev, Dmitry Samigullin, Dmitry Samigullin, Dmitry Samigullin, Nikita Zhilyakov, Nikita Zhilyakov, Nijaz Fatikhov, Ellya Bukharaeva, Ellya Bukharaeva, Alexej Verkhratsky, Evgeny Nikolsky, Evgeny Nikolsky, Evgeny Nikolsky   +14 more
doaj   +1 more source

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton

, 2005
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core  

Primary structure and biochemical properties of an M2 muscarinic receptor

, 1987
A partial amino acid sequence obtained for porcine atrial muscarinic acetylcholine receptor was used to isolate complementary DNA clones containing the complete receptor coding region.
Smith, D. H., Capon, D. J., Schimerlik, M. I., Ramachandran, J., Winslow, J. W., Peterson, G. L., Ashkenazi, A., Peralta, E. G.   +7 more
core   +1 more source

Uniqueness of Supramolecular Systems

Macromolecular Materials and Engineering, Volume 311, Issue 5, May 2026.
Thanks to the variety of classes of supramolecular systems, they have been widely used in various applications. For example, in sensing devices, catalysis, and biomedicine. An example of a conventional photovoltaic material converted into electrical energy. Selective UV or NIR absorbers are required to produce materials with low or no coloration.
José A. Sánchez‐Fernández
wiley   +1 more source

Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome

Molecular Pain, 2018
Complex regional pain syndrome is an extremely painful condition that develops after trauma to a limb. Complex regional pain syndrome exhibits autoimmune features in part mediated by autoantibodies against muscarinic‐2 acetylcholine (M2) receptor.
Veronica I Shubayev, Alex Y Strongin, Tony L Yaksh   +2 more
doaj   +1 more source

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels

, 2005
The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and ...
Abogadie, FC, Tatulian, L, Hughes, S, Brown, DA, Marsh, SJ, Winks, JS, Filippov, AK   +6 more
core  

Transcriptional regulation of the human muscarinic M2 receptor gene [PDF]

, 2003
Muscarinic M2 receptors are important regulators of airway smooth muscle tone and alteration in M2 receptor function has been described in asthmatic patients.
Swan, Caroline, Billington, Charlotte K., Richards, Susan, Felice, Alex E., Ellul-Micallef, Roger, Hunter, Therese, Ebejer, Martin J., Fenech, Anthony G.   +7 more
core  

Effect of inflammatory cell mediators on M2 muscarinic receptors in the lungs

Life Sciences, 1993
Acetylcholine released from vagal nerve endings constricts airways by stimulating M3 muscarinic receptors on the airway smooth muscle. At the same time, released acetylcholine feeds back onto inhibitory M2 muscarinic autoreceptors on the nerve endings, limiting further release of acetylcholine.
A D, Fryer, D B, Jacoby
openaire   +2 more sources

Ozone-induced airway hyperresponsiveness and loss of neuronal M2 muscarinic receptor function

, 1994
The effect of acute ozone exposure on the function of efferent parasympathetic nerves, M3 muscarinic receptors on airway smooth muscle, and inhibitory M2 muscarinic receptors on the parasympathetic nerves was studied.
A. H. Schultheis, D. J. Bassett, A. D. Fryer   +2 more
core   +1 more source

Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats

Journal of Pharmacological Sciences, 2005
SART (specific alternation of rhythm in temperature)-stressed rats are an animal model of autonomic imbalance created by exposing animals to repeated cold stress. The SART-stressed rats have been shown to easily develop orthostatic hypotension (OH).
Taeko Hata, Yoshinori Funakami, Eiji Itoh   +2 more
doaj   +1 more source