Results 231 to 240 of about 77,428 (274)

Bone metabolism in primary hyperparathyroidism. [PDF]

open access: yesWien Klin Wochenschr
Kerschan-Schindl K   +4 more
europepmc   +1 more source

The Parathyroid Hormone Receptor Type 1

, 2020
This chapter describes the molecular and structural properties of the parathyroid hormone receptor type 1 (PTHR1), with emphasis on mechanisms of ligand binding and signal activation, as well as therapeutic applications. The basic protein architecture and mechanistic actions of the PTHR1 can now be viewed in light of the recently reported X-ray crystal
T. Gardella
semanticscholar   +2 more sources

The molecular actions of parathyroid hormone/parathyroid hormone–related protein receptor type 1 and their implications

, 2020
Parathyroid hormone (PTH) and parathyroid hormone–related protein (PTHrP) act on target organs through one common receptor, PTH/PTHrP receptor type 1 (PTH1R).
M. Mannstadt, Marc N. Wein
semanticscholar   +2 more sources

Calcium mobilization from fish scales is mediated by parathyroid hormone related protein via the parathyroid hormone type 1 receptor.

Regulatory Peptides, 2005
The scales of bony fish represent a significant reservoir of calcium but little is known about their contribution, as well as of bone, to calcium balance and how calcium deposition and mobilization are regulated in calcified tissues. In the present study we report the action of parathyroid hormone-related protein (PTHrP) on calcium mobilization from ...
J. Rotllant   +5 more
semanticscholar   +4 more sources

Primary cilia mediate parathyroid hormone receptor type 1 osteogenic actions in osteocytes and osteoblasts via Gli activation

Journal of Cellular Physiology, 2020
Mechanical stimulation of primary cilia in osteocytes and osteoblasts has been proposed as a mechanism that participates in bone cell survival and skeletal remodeling. Among different signaling pathways stimulated by primary cilia, the hedgehog signaling
Eduardo Martín-Guerrero   +5 more
semanticscholar   +3 more sources

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