Results 161 to 170 of about 148,079 (360)

Increased osteoclastic activity in acute Charcot's osteoarthopathy: the role of receptor activator of nuclear factor-kappa B ligand.

open access: yesEuropean review for medical and pharmacological sciences, 2010
AIMS/HYPOTHESIS: Our aims were to compare osteoclastic activity between patients with acute Charcot's osteoarthropathy and diabetic and healthy controls, and to determine the effect of the receptor activator of nuclear factor-kappaB ligand (RANKL) and its decoy receptor osteoprotegerin (OPG).
Pandolfi, Franco   +4 more
openaire   +2 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

open access: yesAdvanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang   +9 more
wiley   +1 more source

The influence of uremic toxins on low bone turnover disease in chronic kidney disease

open access: yesTzu Chi Medical Journal
Uremic toxins play a crucial role in the development of low bone turnover disease in chronic kidney disease (CKD) through the induction of oxidative stress.
Giou-Teng Yiang   +6 more
doaj   +1 more source

Histological Grade and Tumor Stage Are Correlated with Expression of Receptor Activator of Nuclear Factor Kappa b (Rank) in Epithelial Ovarian Cancers. [PDF]

open access: yesInt J Mol Sci, 2022
Gomez R   +8 more
europepmc   +1 more source

Effect of Regiochemistry on Doping and Thermoelectric Properties of n‐Doped Fullerene Derivatives

open access: yesAdvanced Electronic Materials, EarlyView.
Three fullerene derivatives doubly substituted with diethylene glycol chains (PDEG‐2) is presented. The different regiochemistry significantly affects the crystallinity and consequently the dielectric properties, electronic transport, and doping efficiency. By striking a balance between compatibility with the molecular dopant N‐DMBI and crystallinity a
Federico Ferrari   +7 more
wiley   +1 more source

Ultraviolet B‐induced immunosuppression is not associated with receptor activator of nuclear factor kappa B ligand upregulation in human skin [PDF]

open access: bronze, 2018
Étienne Saint‐Cyr Proulx   +6 more
openalex   +1 more source

Facile and Rapid Fabrication of Thermoelectric Legs via Filtration of Doped Polymer Suspension

open access: yesAdvanced Energy Materials, EarlyView.
A vacuum‐filtration method using polymer‐dopant suspensions enables rapid fabrication of tens‐of‐micrometers‐thick, uniformly doped polymer films. Excess dopants and short‐conjugated polymer chains are effectively removed during filtration, reducing structural and energetic disorder.
Eui Hyun Suh   +6 more
wiley   +1 more source

Rethinking Perioperative Corticosteroids in Esophageal Cancer Surgery: Evidence From an Integrative Meta‐Analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Esophagectomy remains a highly invasive procedure associated with substantial postoperative morbidity. Pulmonary complications, anastomotic leakage, and in‐hospital mortality are of particular concern. Perioperative corticosteroids are often administered to attenuate excessive inflammatory responses; however, the clinical impact in ...
Tomohiko Yasuda   +4 more
wiley   +1 more source

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