Results 91 to 100 of about 59,132 (205)
Transcriptional regulation of endothelin-1 expression by advanced glycation end-products in human aortic endothelium is mediated via NF-kappaΒ and AP-1 [PDF]
, 2012 Advanced Glycation End-products (AGEs) are produced by the non-enzymatic glycation of proteins, lipids and nucleic acids, resulting in an overload of highly reactive molecules of endogenous or exogenous (dietary) origin.
Adamopoulos, Christos +6 more
core
Opposing effects of bisphosphonates and advanced glycation end-products on osteoblastic cells [PDF]
, 2008 Patients with long-standing Diabetes mellitus can develop osteopenia and osteoporosis. We have previously shown that advanced glycation endproducts reduce the bone-forming activity of osteoblasts.
Arnol, Verónica +4 more
core +2 more sources
Serum markers of bone fragility in type-2 diabetes mellitus [PDF]
, 2019 Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction ...
Dănciulescu Miulescu, Rucsandra +5 more
core +1 more source
Advanced glycation end products modulate transcriptional regulation in mesangial cells [PDF]
, 1996 Advanced glycation end products modulate transcriptional regulation in mesangial cells. Advanced glycation end products (AGEs) stimulate synthesis of extracellular matrix (ECM) in a receptor-mediated manner on mesangial cells.
Iehara, Noriyuki +4 more
core +1 more source
Clinical Interventions in Aging, 2014 Yanzi Cheng,1 Jiwen Zhong,1 Yang Xiang,1 Fan Zeng,1 Dehong Cai,2,† Ling Zhao11Department of Intensive Care Unit, Zhuhai People’s Hospital, Zhuhai, Guangdong, People’s Republic of China; 2Department of Endocrinology, Zhujiang Hospital ...
Cheng YZ +5 more
doaj
Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke [PDF]
, 2013 : Stroke is a major cause of mortality and disability worldwide. The main cause of stroke is atherosclerosis, and the most common risk factor for atherosclerosis is hypertension. Int. J. Mol. Sci. 2013, 14 18900 Therefore, antihypertensive treatments are
Eiichiro Tanaka +8 more
core +2 more sources
Role of the receptor for advanced glycation end products inhepatic fbrosis
World Journal of Gastroenterology, 2009 To study the role of advanced glycation end products (AGE) and their specific receptor (RAGE) in the pathogenesis of liver fibrogenesis.In vitro RAGE expression and extracellular matrix-related gene expression in both rat and human hepatic stellate cells (HSC) were measured after stimulation with the two RAGE ligands, advanced glycation end product ...
Christina, Lohwasser +4 more
openaire +2 more sources
Cellular Physiology and Biochemistry, 2013 Background: Given the roles of receptor for advanced glycation end products (RAGE) in the pathogenesis of carcinogenesis, we propose that RAGE polymorphisms may be associated with risk of epithelial ovarian carcinoma (EOC).
Shuquan Zhang +5 more
doaj +1 more source
Cellular Signalling, 2013 Firstly described in 1992, the receptor for advanced glycation end-products has attracted increasing attention due to its diverse ligand repertoire and involvement in several pathophysiological processes associated with inflammation such as in diabetes, cancer, autoimmune diseases and neurodegenerative diseases. This receptor in addition to its binding
Rojas, Armando +5 more
openaire +4 more sources
A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis
Cell Reports, 2019 Summary: Exquisite regulation of energy homeostasis protects from nutrient deprivation but causes metabolic dysfunction upon nutrient excess. In human and murine adipose tissue, the accumulation of ligands of the receptor for advanced glycation end ...
Carmen Hurtado del Pozo +15 more
doaj +1 more source