Results 81 to 90 of about 38,510 (295)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Endocrinology, Diabetes & Metabolism, 2021
Aims The accumulation of advanced glycation end products is implicated in the development and progression of diabetic kidney disease. No study has examined whether stimulating advanced glycation clearance via receptor manipulation is reno‐protective in ...
Aowen Zhuang, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin L. Schulz, Josephine M. Forbes   +10 more
doaj   +1 more source

Receptor for advanced glycation end products is overexpressed in psoriatic plaques independent of disease severity

, 2017
Enhanced expression and excitation of the receptor for advanced glycation end products is considered to play a role in the regulation of many pro-inflammatory genes involved in the pathogenesis of psoriasis.We investigated the expression of receptor for ...
Akin Aktas, Karaismailoglu, Eda, Aktas, Akin, Sungu, Nuran, Gulsen Akoglu, Ozgor, Ozkay, Ozkay Ozgor, Nuran Sungu, Akoglu, Gulsen, Eda Karaismailoglu   +9 more
core   +1 more source

Advanced glucose control strategies leveraging Raman spectroscopy for optimized mammalian cell culture manufacturing

Biotechnology Progress, EarlyView.
Abstract Maintaining consistent quality in the manufacturing of biotherapeutic proteins in mammalian cell culture is challenging, with unplanned deviations causing inconsistencies and potential batch failure. Current methods for monitoring and controlling critical process parameters (CPPs) rely on slow, labor‐intensive offline analyses.
Matthew Banner, Daniel Ray, Irfan Ahanger, Fabio Zurlo, Noah Hitchcock, Rajesh Mistry, Kasia Kozakowska‐McDonnell, Matthew Cheeks, Richard Turner, Jonathan Welsh, Suzanne S. Farid, Michael Thomas, Stephen Goldrick   +12 more
wiley   +1 more source

Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2016
Tetsuro Kamo, Sadatomo Tasaka, Yuriko Tokuda, Shoji Suzuki, Takanori Asakura, Kazuma Yagi, Ho Namkoong, Makoto Ishii, Naoki Hasegawa, Tomoko Betsuyaku   +9 more
doaj   +1 more source

The AGE–RAGE–oxidative stress axis: A paradigm shift in understanding diabetic retinopathy

Indian Journal of Ophthalmology
Diabetic retinopathy (DR) represents a vision-threatening complication of diabetes, characterized by progressive damage to the retinal neurovascular network in both type 1 and type 2 diabetes.
Riya Srivastava, Deepak Mishra, Dipti Singh, M Yashwant Reddy, Samvidha Parihar, Kamlesh Palandurkar   +5 more
doaj   +1 more source

Explore the mechanism of puerarin to improve diabetic peripheral neuropathy in rats based on AGEs/RAGE signaling pathway [PDF]

Yixue xinzhi zazhi
Objective To explore the ameliorative effect of puerarin on diabetic peripheral neuropathy (DPN) in rats and its possible mechanism.Methods A total of 50 SD rats were randomly divided into control group, model group (DPN model was constructed), low-dose ...
HAO Lu, SHI Mingyang, CHEN Yan, YANG Shan   +3 more
doaj   +1 more source

Interaction of receptor for advanced glycation end products with advanced oxidation protein products induces podocyte injury

, 2012
Chronic kidney disease (CKD) is characterized by progressive decline in renal function. Podocyte dropouts contribute to the pathogenesis of diabetic and nondiabetic CKD.
Yamamoto, Yasuhiko, Yamamoto, Hiroshi
core   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Skin autofluorescence in diabetes mellitus [PDF]

, 2008
AGEs ofwel advanced glycation endproducts zijn onomkeerbaar versuikerde stoffen, die voornamelijk aan eiwitten zijn gekoppeld, en die bij ieder mens stapelen. Bij iemand met diabetes mellitus gaat dit proces echter versneld.
Lutgers, Helen Lucia, Lutgers, H.L.,, Lutgers, H.L.   +2 more
core