Results 91 to 100 of about 82,871,848 (297)

Explore the mechanism of puerarin to improve diabetic peripheral neuropathy in rats based on AGEs/RAGE signaling pathway [PDF]

Yixue xinzhi zazhi
Objective To explore the ameliorative effect of puerarin on diabetic peripheral neuropathy (DPN) in rats and its possible mechanism.Methods A total of 50 SD rats were randomly divided into control group, model group (DPN model was constructed), low-dose ...
HAO Lu, SHI Mingyang, CHEN Yan, YANG Shan   +3 more
doaj   +1 more source

Correction: S100A14 Stimulates Cell Proliferation and Induces Cell Apoptosis at Different Concentrations via Receptor for Advanced Glycation End Products (RAGE). [PDF]

, 2016
Correction: S100A14 Stimulates Cell Proliferation and Induces Cell Apoptosis at Different Concentrations via Receptor for Advanced Glycation End Products (RAGE)
Zhihua Liu (59139), Hongyan Chen, Qing'e Jin (222695), Qing'e Jin, Fang Ding, Hongyan Chen (87846), Aiping Luo (222706), Aiping Luo, Fang Ding (222713), Zhihua Liu   +9 more
core   +1 more source

The Impact of Glycation on Protein Digestibility

ChemFoodChem, EarlyView.
Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann, Simone Lipinski, Jana Raupbach   +2 more
wiley   +1 more source

Role of the receptor for advanced glycation end products inhepatic fbrosis

World Journal of Gastroenterology, 2009
To study the role of advanced glycation end products (AGE) and their specific receptor (RAGE) in the pathogenesis of liver fibrogenesis.In vitro RAGE expression and extracellular matrix-related gene expression in both rat and human hepatic stellate cells (HSC) were measured after stimulation with the two RAGE ligands, advanced glycation end product ...
Christina, Lohwasser, Daniel, Neureiter, Yury, Popov, Michael, Bauer, Detlef, Schuppan   +4 more
openaire   +2 more sources

Homodimerization Is Essential for the Receptor for Advanced Glycation End Products (RAGE)-mediated Signal Transduction [PDF]

, 2010
The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor that binds to diverse ligands and initiates a downstream proinflammatory signaling cascade.
Alan W. Stitt, Ward, Micheal, Elliott, Christopher T., Mark H. Mooney, Christopher T. Elliott, Mooney, Mark H., Angelina Madden, Madden, Angelina, Hongliang Zong, Micheal Ward, Stitt, Alan W.; id_orcid, Zong, Hongliang, Stitt, Alan W., Mooney, Mark H.; id_orcid   +13 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review

Molecular Medicine, 2018
Background Traditional risk factors are insufficient to explain all cases of coronary artery disease (CAD) in patients with diabetes mellitus (DM). Advanced glycation end-products (AGEs) and their receptors may play important roles in the development and
Sarah Louise Fishman, Halis Sonmez, Craig Basman, Varinder Singh, Leonid Poretsky   +4 more
doaj   +1 more source

Receptor for advanced glycation end products is overexpressed in psoriatic plaques independent of disease severity

, 2017
Enhanced expression and excitation of the receptor for advanced glycation end products is considered to play a role in the regulation of many pro-inflammatory genes involved in the pathogenesis of psoriasis.We investigated the expression of receptor for ...
Akin Aktas, Karaismailoglu, Eda, Aktas, Akin, Sungu, Nuran, Gulsen Akoglu, Ozgor, Ozkay, Ozkay Ozgor, Nuran Sungu, Akoglu, Gulsen, Eda Karaismailoglu   +9 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Clinical Factors and Biomarkers Associated with Depressive Disorders in Older Patients Affected by Chronic Kidney Disease (CKD): Does the Advanced Glycation End Products (AGEs)/RAGE (Receptor for AGEs) System Play Any Role?

Geriatrics
Depressive disorders are highly prevalent among subjects suffering from chronic kidney disease (CKD). The aim of the present study is to evaluate clinical and biochemical factors associated with depressive disorders in a sample of older CKD patients ...
Massimiliano Buoli, Elena Dozio, Lara Caldiroli, Silvia Armelloni, Elena Vianello, Massimiliano Corsi Romanelli, Giuseppe Castellano, Simone Vettoretti   +7 more
doaj   +1 more source