Results 51 to 60 of about 59,132 (205)

From human Megakaryocytes to platelets: Effects of aspirin on high-mobility group Box 1/receptor for advanced glycation end products axis [PDF]

, 2018
Platelets (PLTs) are the major source of high-mobility group box 1 (HMGB1), a protein that is involved in sterile inflammation of blood vessels and thrombosis.
Alessandra Zicari, Emanuela Mari, Fabio M. Pulcinelli, Isabella Massimi, Marco E. Bianchi, Marco Tafani, Marco Tafani, Ornella Morsilli, Raffaella Guerriero, Stefania Mardente   +9 more
core   +2 more sources

Advanced glycation end products (AGEs) promote melanogenesis through receptor for AGEs [PDF]

Scientific Reports, 2016
AbstractAccumulation of advanced glycation end products (AGEs) is linked with development or aggravation of many degenerative processes or disorders, including aging and atherosclerosis. AGEs production in skin cells is known to promote stiffness and loss of elasticity through their buildup in connective tissue.
Eun Jung Lee, Ji Young Kim, Sang Ho Oh
openaire   +3 more sources

Transthyretin and Receptor for Advanced Glycation End Product’s Differential Levels Associated with the Pathogenesis of Rheumatoid Arthritis

Journal of Inflammation Research, 2021
Monu,1,2 Prachi Agnihotri,1 Mohd Saquib,1,2 Ashish Sarkar,1,2 Debolina Chakraborty,1,2 Uma Kumar,3 Sagarika Biswas1 1Council of Scientific and Industrial Research -Institute of Genomics & Integrative Biology (CSIR–IGIB), Delhi, 110007, India; 2Academy of
Monu, Agnihotri P, Saquib M, Sarkar A, Chakraborty D, Kumar U, Biswas S   +6 more
doaj  

A new gender-specific model for skin autofluorescence risk stratification [PDF]

, 2015
Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS, Damanhouri, ZA, Holmes, E, Kimhofer, T, Mosli, HH   +4 more
core   +1 more source

Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]

Journal of Kerman University of Medical Sciences, 2014
Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary, Sayedeh Zahra Bathaie, Fereshteh Bahmani, Gholamreza Moshtaghi Kashanian   +3 more
doaj  

Weight Increase Is Associated with Skeletal Muscle Immunostaining for Advanced Glycation End Products, Receptor for Advanced Glycation End Products, and Oxidation Injury

Rejuvenation Research, 2008
Background: Tissue accumulation of advanced glycation end products (AGEs) is associated with ageing, both in diabetics and nondiabetic subjects. Aim: The purpose of this study was to assess immunostaining for AGEs, specifically ...
Maza Cave, María Pía de la, Uribarri, Jaime, Olivares, Daniela, Hirsch Birn, Sandra, Leiva Balich, Laura, Bunout Barnett, Daniel, Barrera Acevedo, María Gladys   +6 more
openaire   +4 more sources

Participation of the Receptor for Advanced Glycation End Products in Efferocytosis [PDF]

The Journal of Immunology, 2011
Abstract Clearance of apoptotic cells by macrophages and other phagocytic cells, called efferocytosis, is a central process in the resolution of inflammation. Although the receptor for advanced glycation end products (RAGE) has been shown to participate in a variety of acute and chronic inflammatory processes in the lungs and other ...
Arnaud, Friggeri, Sami, Banerjee, Subrata, Biswas, Andressa, de Freitas, Gang, Liu, Angelika, Bierhaus, Edward, Abraham   +6 more
openaire   +2 more sources

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source

The Anti-AGEing and RAGEing Potential of Isothiocyanates

Molecules
Isothiocyanates (ITCs), found in edible plants such as cruciferous vegetables, are a group of reactive organo-sulfur phytochemicals produced by the hydrolysis of precursors known as glucosinolates.
Bradley A. Krisanits, Bhoomika Kaur, Jed W. Fahey, David P. Turner   +3 more
doaj   +1 more source

Higher levels of the soluble receptor for advanced glycation end products and lower levels of the extracellular newly identified receptor for advanced glycation end products were associated with lipid-lowering drugs in patients with type 1 diabetes: a comparative cross-sectional study

Lipids in Health and Disease, 2020
Background The receptors for advanced glycation end products (RAGE) are increased in atherosclerotic plaques. Soluble (s)RAGE decreases, whereas the extracellular newly identified receptor for advanced glycation end products (EN-RAGE) increases ...
Eva O. Melin, Jonatan Dereke, Magnus Hillman   +2 more
doaj   +1 more source