Reduced soluble receptor for advanced glycation end-products in COPD [PDF]
The soluble receptor for advanced glycation end-products (sRAGE) has anti-inflammatory properties, and deficiency of circulating sRAGE is associated with various human diseases. Whether sRAGE concentrations are reduced in chronic obstructive pulmonary disease (COPD) has not been determined.
Smith, D. J. +5 more
openaire +4 more sources
Advanced glycation end products (AGEs) exert their cellular effects on cells by interacting with specific cellular receptors, the best characterized of which is the receptor for AGE (RAGE).
H. Lander +5 more
semanticscholar +1 more source
From human Megakaryocytes to platelets: Effects of aspirin on high-mobility group Box 1/receptor for advanced glycation end products axis [PDF]
Platelets (PLTs) are the major source of high-mobility group box 1 (HMGB1), a protein that is involved in sterile inflammation of blood vessels and thrombosis.
Alessandra Zicari +9 more
core +2 more sources
Receptor of advanced glycation end products in childhood asthma exacerbation
AbstractBackgroundReceptor of advanced glycation end products (RAGE) is a new marker of inflammation in different inflammatory disorders. Bronchial asthma as an inflammatory disease is associated with increased levels of many markers of inflammation which are used to evaluate the severity of childhood asthma, and may be the targets of new therapeutic ...
Adel Salah Bediwy +2 more
openaire +3 more sources
Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]
Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary +3 more
doaj
Receptor for advanced glycation end-products and ARDS prediction: a multicentre observational study
Acute respiratory distress syndrome (ARDS) prediction remains challenging despite available clinical scores. To assess soluble receptor for advanced glycation end-products (sRAGE), a marker of lung epithelial injury, as a predictor of ARDS in a high-risk
M. Jabaudon +19 more
semanticscholar +1 more source
Prothrombin is a binding partner of the human receptor of advanced glycation end products [PDF]
The receptor for advanced glycation end products (RAGE) plays a key role in mammal physiology and in the etiology and progression of inflammatory and oxidative stress-based diseases. In adults, RAGE expression is normally high only in the lung where the protein concentrates in the basal membrane of alveolar Type I epithelial cells.
Angela Raucci +8 more
openaire +4 more sources
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
IntroductionThere remains a need to better identify patients at highest risk for developing severe Coronavirus Disease 2019 (COVID-19) as additional waves of the pandemic continue to impact hospital systems.
Zachary A. Matthay +30 more
doaj +1 more source
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji +12 more
wiley +1 more source

